Results 71 to 80 of about 3,597,475 (336)

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Treated Incidence of Psychotic Disorders in the Multinational EU-GEI Study

JAMA psychiatry, 2017
Importance Psychotic disorders contribute significantly to the global disease burden, yet the latest international incidence study of psychotic disorders was conducted in the 1980s.
H. Jongsma, C. Gayer-Anderson, A. Lasalvia, D. Quattrone, A. Mulè, A. Szöke, J. Selten, Caitlin Turner, C. Arango, I. Tarricone, D. Berardi, A. Tortelli, P. Llorca, L. de Haan, J. Bobes, M. Bernardo, J. Sanjuán, J. Santos, M. Arrojo, C. Del-Ben, P. Menezes, R. Murray, B. Rutten, Peter B. Jones, J. van os, C. Morgan, J. Kirkbride   +26 more
semanticscholar   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Raised preoperative monocyte chemoattractant protein-1 as the independent predictor of delirium after cardiac surgery. A prospective cohort study

European Psychiatry, 2021
Introduction Delirium is a frequent and serious complication of cardiac surgery. However, the knowledge regarding pathogenesis of postoperative delirium is limited.
J. Kaźmierski, P. Miler, A. Pawlak, H. Jerczyńska, E. Frankowska, J. Woźniak, K. Woźniak, A. Brzezińska, M. Wilczyński   +8 more
doaj   +1 more source

Extreme overvalued beliefs: How violent extremist beliefs become “normalized” [PDF]

, 2018
Extreme overvalued beliefs (EOB) are rigidly held, non-deusional beliefs that are the motive behind most acts of terrorism and mass shootings. EOBs are differentiated from delusions and obsessions. The concept of an overvalued idea was first described by
Rahman, Tahir
core   +3 more sources

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults with Inflammatory Bowel Disease: Data from a Large Administrative Claims Cohort

Arthritis Care &Research, Accepted Article.
Objectives The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in this population, but safety data are mixed. Methods This retrospective cohort study included patients with IBD ≥ 18 years of age from Optum's de‐identified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Patients’ experience of patient-reported outcomes, continuous feedback, and a solution-focused approach (using DIALOG +) in psychosis care in Sweden

BMC Psychiatry
Background Involving patients in care and ensuring structured continuous follow-up can be challenging. Using Patient-Reported Outcomes during routine encounters can enable patients and healthcare professionals to collaboratively focus on the patients ...
Marcus Lundmark, Katarina Allerby, Andreas Gremyr, Ann-Christine Andersson   +3 more
doaj   +1 more source

Serum levels of S100B in patients with chronic schizophrenia during treatment augmentation with sarcosine: results of the double-blind, randomized, placebo-controlled PULSAR study

Frontiers in Pharmacology
IntroductionSarcosine (N-methylglycine) normalizes glutamatergic neurotransmission in schizophrenia and ameliorates primary negative symptoms. This amino acid may also directly or indirectly influence glial function and therefore levels of S100B, calcium-
Agnieszka Pawlak, Adam Wysokiński, Dominik Strzelecki   +2 more
doaj   +1 more source

Prevalence and risk factors for depressive symptom in methamphetamine use disorder

Stress and Brain, 2021
Background:Methamphetamine use disorder (MUD) is a severe public health problem, accompanying physical and psychological impairment. Depression is a common comorbidity with MUD, which is associated with poor treatment outcome. The objective of this study
Ziqi Liu, Yi Zhang, Ti-Fei Yuan
doaj   +1 more source