Results 31 to 40 of about 107,636 (348)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

The activation of GABAergic neurons in the hypothalamic tuberomammillary nucleus attenuates sevoflurane and propofol-induced anesthesia in mice

Frontiers in Pharmacology, 2023
Background: The histaminergic neurons in the hypothalamic tuberomammillary nucleus (TMN) have been suggested to play a vital role in maintaining a rising state.
Jing Liu, Jing Liu, Jing Liu, Jing Liu, Xiao Liu, Xiao Liu, Xiao Liu, Wen-Yu Zhou, Wen-Yu Zhou, Wen-Yu Zhou, Jun Gan, Jun Gan, Jun Gan, Jie Wang, Jie Wang, Jie Wang, Qi Zhang, Qi Zhang, Qi Zhang, Jun-Liang Li, Jun-Liang Li, Jun-Liang Li, Zhong-Shan Shen, Zhong-Shan Shen, Zhong-Shan Shen, Yue-Ying Zhang, Qiong-Yao Tang, Qiong-Yao Tang, Qiong-Yao Tang, Zhe Zhang, Zhe Zhang, Zhe Zhang   +31 more
doaj   +1 more source

Incidence and correlates of delirium in a West African mental health clinic [PDF]

, 2010
Objective: <br/> <br/> To determine the incidence of delirium in those patients presenting to a psychiatric clinic in Nigeria and to examine if any demographic or clinical variables were correlated with this diagnosis. <br/> <br/
Abiodun, Abiodun, Abiodun, Adamis, Adebayo Rasheed Erinfolami, Adeyemi, Aghanwa, Aghanwa, Andrew Olagunju, APA, Armstrong, Bolanle Adeyemi Ola, Brown, Burns, Cole, Cookson, Francis, Inouye, Jim Crabb, Kiely, Kishi, Koran, Koranyi, Meagher, Melka, Nubukpo, Pompei, Rajeev Krishnadas, Rockwood, Rolfson, Semple, Siddiqi, Sirois, SPSS Inc., Swigart, Taylor, Trzepacz, Trzepacz, van Hemert, Vanpee, Waszynski, Wei, WHO, WHO, WHO, Zou   +45 more
core   +1 more source

Relationship Between Use of Dementia-Specific Nursing Institutions and Psychotropic Drugs, Mortality, and Morbidity [PDF]

BJPsych Open
Lee J, Lee B.
europepmc   +3 more sources

De l’activité pharmacologique à l’usage des drogues : la construction des connaissances sur les psychotropes [PDF]

, 1997
Les effets des drogues sont des événements complexes dans la vie des usagers. Que savons-nous des effets des plus importants psychotropes et comment en sommes-nous arrivés à ces connaissances ?
Montagne, Michael
core   +1 more source

Outpatient Civil Commitment in North Carolina: Constitutional and Policy Concerns [PDF]

, 1995
Outpatient commitment of the mentally ill is court-ordered treatment in the community and is usually characterized by short, recurring visits to a mental health clinic that provides treatment such as medication, individual or group therapy, day or part ...
Karimi, Saadat, Zamanov, Asaf
core   +3 more sources

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

Advanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li, Huiyang Huang, Cunhao Hu, Xuan Zhang, Song Lin, Xiaodan Huang, Ti‐fei Yuan, Kwok‐Fai So, Lu Huang, Chaoran Ren, Qian Tao   +10 more
wiley   +1 more source

Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson’s disease model mice

Cell Death and Disease
Neuroinflammation is a key factor in the pathogenesis of Parkinson’s disease (PD). Activated microglia in the central nervous system (CNS) and infiltration of peripheral immune cells contribute to dopaminergic neuron loss. However, the role of peripheral
Wei Song, Zi-ming Zhou, Le-le Zhang, Hai-feng Shu, Jin-ru Xia, Xia Qin, Rong Hua, Yong-mei Zhang   +7 more
doaj   +1 more source

The prevalence and incidence of mental ill-health in adults with autism and intellectual disabilities [PDF]

, 2008
The prevalence, and incidence, of mental ill-health in adults with intellectual disabilities and autism were compared with the whole population with intellectual disabilities, and with controls, matched individually for age, gender, ability-level, and ...
A. V. Brereton, Alison Jackson, B. Holden, C. Lord, C. Morgan, C. W. McGrother, Craig A. Melville, D. G. Allen, D. Mantry, Dipali Mantry, E. A. Bradley, E. A. Bradley, E. Billstedt, E. Smiley, E. Tsakanikos, E. Tsakanikos, Elita Smiley, F. Tyrer, G. Baird, G. Dawson, H. Leonard, H. Schrojenstein Lantman-de Valk van, H. W. M. Kwok, J. Bertrand, J. Hill, J. K. Kern, J. L. Matson, J. L. Matson, J. Robertson, Janet Finlayson, Jill Morrison, K. McClintock, L. Lecavalier, L. Wing, Linda Allan, M Yeargin-Allsopp, M. E. Stewart, M. G. Aman, M. Ghaziuddin, M. Ghaziuddin, M. Hotopf, M. M. Konstantareas, M. Wullink, N. Holmes, National Initiative: Autism Screening, Assessment, P. A. Filipek, P. Sturmey, P. W. Davidson, R. A. Collacott, R. Didden, R. Didden, R. Farmer, R. M. Reese, S. -A. Cooper, S. -A. Cooper, S. A. Borthwick-Duffy, S. A. Cooper, S. A. Cooper, S. Bhaumik, S. Chakrabarti, S. Chakrabarti, S. Deb, S. Moss, Sally-Ann Cooper, Scottish Intercollegiate Guideline Network, T. D. Cook, World Health Organisation, World Health Organisation   +67 more
core   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source