Results 41 to 50 of about 100,051 (354)

Effects of Dictyophora polysaccharide on cerebellar Purkinje cell degeneration in a chronic alcohol mouse model

Animal Models and Experimental Medicine, EarlyView.
In an ethanol (EtOH)‐treated mouse model, increases in the NLRP3 inflammasome proteins, PC degeneration, and motor coordination disorders were observed. DIP suppressed the NLRP3‐ASC‐caspase‐1 signaling pathway, and alleviated the motor deficits and cerebellar pathological changes in chronic EtOH‐treated mice.
Jian Zhang, Zhihui Dai, Huanhuan Yu, Baofei Sun, Jiuyang Ding, Yuanhe Wang   +5 more
wiley   +1 more source

Gut microbes–spinal connection is required for itch sensation

Gut Microbes
The gut microbiota has been linked to a number of neurological disorders. However, it is unclear whether the gut microbiota is involved in the genesis of chronic itch, a refractory condition that afflicts patients both physically and mentally.
Tong Jin, Si-Yuan Li, Hong-Li Zheng, Xiao-Dan Liu, Yue Huang, Gan Ma, Ya-Xuan Zhao, Xiao-Tian Zhao, Li Yang, Qi-Hui Wang, Hong-Jun Wang, Chengyong Gu, Zhiqiang Pan, Fuqing Lin   +13 more
doaj   +1 more source

The PrLGlu→avBNSTGABA circuit rapidly modulates depression-like behaviors in male mice

iScience, 2023
Summary: Depression is a global disease with a high prevalence. Here, we examine the role of the circuit from prelimbic mPFC (PrL) to the anterior ventral bed nucleus of the stria terminalis (avBNST) in depression-like mice through behavioral tests ...
Jie-ying Chen, Ke Wu, Miao-miao Guo, Wei Song, Si-ting Huang, Yong-mei Zhang   +5 more
doaj  

Mental health nurses’ medicines management role: a qualitative content analysis [PDF]

, 2016
Aim: This study explores medicines management role undertaken by mental health nurses (MHN) in a wide variety of clinical specialisms and contexts. Method: Ten MHNs were interviewed and audiotaped.
Hemingway, Steve
core   +1 more source

Implementing physician‐led medication reviews for patients with diabetes and severe mental disorder: A randomized controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims Patients with severe mental disorder and diabetes may be exposed to inappropriate polypharmacy increasing the risk of side effects and drug interactions. Although medication reviews may facilitate short‐term deprescribing, they are not known to affect clinical outcomes.
Johan Frederik Mebus Meyer Christensen, Signe Wegmann Düring, Gesche Jürgens   +2 more
wiley   +1 more source

Application of the Sensory Contact Model for Pharmacological Studies under Simulated Clinical Conditions [PDF]

, 2007
The sensory contact model allows forming different psycho-pathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, cognition disturbances, anhedonia, addictive states etc.) produced by repeated agonistic ...
Damira F. Avgustinovich, Irina L. Kovalenko, Michael V. Tenditnik, Natalia N. Kudryavtseva, Natalia P. Bondar   +4 more
core   +1 more source

Psychotropic Drugs in the Aged

Comprehensive Psychiatry, 1977
Abstract Psychological disorders in the aged can be (largely) a result of anatomical brain lesions; but they can also be (largely) of a “functional” nature. In the latter case, deterioration of brain tissue plays no important etiological role, or is a process which merely triggers the complex of psychological disorders.
openaire   +3 more sources

Developing the Inpatient Mental Health Pharmaceutical Assessment and Care Tool (IMPACT) for use by UK mental health pharmacy teams—a modified Delphi study

British Journal of Clinical Pharmacology, EarlyView.
Aims To develop an evidence‐ and consensus‐based patient prioritization tool for use by UK mental health inpatient pharmacy teams. Methods A modified‐Delphi technique was used to obtain experts' agreement on the content, design and practical use of the patient prioritization tool.
Fatima Q. Alshaikhmubarak, Richard N. Keers, Petra Brown, Penny J. Lewis   +3 more
wiley   +1 more source

Incidence and correlates of delirium in a West African mental health clinic [PDF]

, 2010
Objective: <br/> <br/> To determine the incidence of delirium in those patients presenting to a psychiatric clinic in Nigeria and to examine if any demographic or clinical variables were correlated with this diagnosis. <br/> <br/
Abiodun, Abiodun, Abiodun, Adamis, Adebayo Rasheed Erinfolami, Adeyemi, Aghanwa, Aghanwa, Andrew Olagunju, APA, Armstrong, Bolanle Adeyemi Ola, Brown, Burns, Cole, Cookson, Francis, Inouye, Jim Crabb, Kiely, Kishi, Koran, Koranyi, Meagher, Melka, Nubukpo, Pompei, Rajeev Krishnadas, Rockwood, Rolfson, Semple, Siddiqi, Sirois, SPSS Inc., Swigart, Taylor, Trzepacz, Trzepacz, van Hemert, Vanpee, Waszynski, Wei, WHO, WHO, WHO, Zou   +45 more
core   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source