Results 71 to 80 of about 5,676,112 (258)

Coagulopathy biomarkers in mild to moderate CoVID-19 patients admitted in a tertiary care public hospital in eastern India [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2021
Background: The present study was undertaken to identify various prognostic biomarkers related to coagulation that may predict the outcome of mild to moderate CoVID-19 patients.
Santasmita Pal   +4 more
doaj  

PT-symmetric square well and the associated SUSY hierarchies

open access: yes, 2002
The PT-symmetric square well problem is considered in a SUSY framework. When the coupling strength $Z$ lies below the critical value $Z_0^{\rm (crit)}$ where PT symmetry becomes spontaneously broken, we find a hierarchy of SUSY partner potentials ...
B. BAGCHI   +6 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Memória: fragmentos de um processo histórico

open access: yesPlural, 2000
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Adríana Thomazoni Claro Roberto
doaj   +1 more source

Platinum and Iridium Oxide Co-modified TiO2 Nanotubes Array Based Photoelectrochemical Sensors for Glutathione

open access: yesNanomaterials, 2020
Oriented TiO2 nanotubes, which are fabricated by anodic oxidation method, are prospective in photoelectrochemical analysis and sensors. In this work, Pt and IrO2 co-modified TiO2 nanotubes array was prepared via a two-step deposition process involving ...
Jing Tian   +8 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Effect of Pt on Zn-Free Cu-Al Catalysts for Methanol Steam Reforming to Produce Hydrogen [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2018
Steam reforming of methanol can be considered as an attractive reaction aiming at hydrogen production for PEM fuel cells. Although Cu/Al-contained catalysts are considerably evaluated in this reaction, further evaluation is essential to evaluate the ...
Mehran Jafari   +3 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

PT-PT Synthetic Speech Detection

open access: yes
Recent developments in the field of artificial intelligence (AI) have led to the creation of powerful generative models. These models have demonstrated such capabilities that it becomes nearly impossible for a human to distinguish between generated and human utterances, between synthetic and natural speech.
Rafael Geraldo dos Santos   +2 more
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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