Results 81 to 90 of about 6,622,332 (365)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Castelo Rá-Tim-Bum: o educativo como entretenimento (resenha)
Linhas Críticas, 2000 Duas “lógicas” diferentes presidem o funcionamento da Educação e da TV. Objetivos, procedimentos, estruturas, institucionalização, a própria história – da escola e da televisão – são tão diversos que a expectativa é a do desencontro. Resenha do livro:
José Luiz Braga
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Nucleobase Stacking Sustained by Pt−Pt Interactions
ChemistryEuropeAbstractThis article reports the use of metal–metal interactions as a way to induce nucleobase stacking in a dinucleotide chain. We synthetized and study a series of C,N‐cyclometallated platinum(II) binuclear complexes derived from 6‐phenylpurine dinucleotide 1 as proligand, and β‐diketonates, 2,2'‐bipyridines and 1,10‐phenanthroline as ancillary ...
Carmen Lorenzo‐Aparicio +4 more
openaire +3 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Coagulopathy biomarkers in mild to moderate CoVID-19 patients admitted in a tertiary care public hospital in eastern India [PDF]
Al Ameen Journal of Medical Sciences, 2021 Background: The present study was undertaken to identify various prognostic biomarkers related to coagulation that may predict the outcome of mild to moderate CoVID-19 patients.
Santasmita Pal +4 more
doaj
PT-Rotations, PT-Spherical Harmonics and the PT-Hydrogen Atom
, 2010 We have constructed a set of non-Hermitian operators that satisfy the commutation relations of the SO(3)-Lie algebra. It is shown that this operators generate rotations in the configuration space and not in the momentum space but in a modified non-Hermitian momentum space.
Romero, Juan M. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
De ontem para hoje, o que aconteceu com o PT?
Revista Espaço Acadêmico, 2009 De lá para cá, o que aconteceu com o PT? Para tentar responder a esta pergunta, o livro “O Partido dos Trabalhadores e a política brasileira (1980-2006): uma história revisitada”, publicado no segundo semestre de 2009 e organizado por Vitor Amorim de ...
Riberti Almeida Felisbino
doaj
Memória: fragmentos de um processo histórico
Plural, 2000 -
Adríana Thomazoni Claro Roberto
doaj +1 more source