Results 131 to 140 of about 22,716 (169)

Novel therapeutic strategies for metastatic castration‑resistant prostate cancer: Beyond androgen receptor pathway inhibition (Review). [PDF]

Int J Oncol
Wang Y, Xie Y, Zhao Q.
europepmc   +1 more source

Role of LONP1 in human diseases: molecular mechanisms and therapeutic potential. [PDF]

Cell Mol Biol Lett
Li M, Wang A, Tang C, Qiao Y, Zhang W, Wu Y.   +5 more
europepmc   +1 more source

CircFN1 modulates IL-1β-induced osteoarthritis through the miR-19b-3p/PTEN signaling axis. [PDF]

Sci Rep
Jiang Y, Wang Q, Yang X, Liu H, Wu H, Wang M, Pan L, Cao Y, Meng Z.   +8 more
europepmc   +1 more source

Preclinical Rationale, Clinical Efficacy, and Safety of the Selective AKT Kinase Inhibitor Capivasertib in Metastatic Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Carcinoma: A Practical Narrative Review. [PDF]

Curr Oncol
Valerio MR, Sambataro D, Martorana F, Greco M, Mesi C, Gebbia V, Vigneri P, Scandurra G.   +7 more
europepmc   +1 more source

Skeletal muscle mitochondrial marker responses to a single bout and 6 weeks of high load versus high volume resistance training in previously trained men. [PDF]

Exp Physiol
Mueller B, Fox CD, Parry HA, Mesquita PHC, Vann CG, Ruple BA, Sexton CL, Godwin JS, McIntosh MM, Beck DT, Young KC, Phillips SM, Kavazis AN, Roberts MD.   +13 more
europepmc   +1 more source

Prenatal Delivery of HIF-1α siRNA Using Transferrin-Modified Lipid Nanoparticles Alleviates Hypoxia-Induced Neurodevelopmental Abnormalities via PTEN/PI3K/AKT Signaling. [PDF]

Int J Nanomedicine
Du F, Bai Y, Bai K, Yang T, Chen J, Li T, Dai Y.   +6 more
europepmc   +1 more source

Pharmacovigilance Signal Detection and Mutually Exclusive Driver Mutations of the PI3K/AKT Pathway in Breast Cancer Treated With Capivasertib. [PDF]

Hum Mutat
Luo Z, Shi Y, Zhu B, Huang Q, Zhang W, Shi Y, Yang X.   +6 more
europepmc   +1 more source

Hypoxic preconditioned mesenchymal stem cell-derived exosomes alleviate oxidative stress-induced cardiomyocyte apoptosis through miR-486-5p. [PDF]

World J Stem Cells
Zeng ZF, Rao J, Xia XB, Chen XY, He HX, Liu B, Chen Q, Liu YD, Wang GJ, Cheng PC, Wang JN, Wang P, Yu Y, Wang ZN.   +13 more
europepmc   +1 more source

A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review). [PDF]

Int J Mol Med
Li T, Chen H, Zhao P, Yin C, Song Z.
europepmc   +1 more source

Mitofusin MFN2 acts as a molecular sensor preventing protein aggregation and mitophagy, with a protective effect against apoptosis in Charcot-Marie-Tooth type 2A disease. [PDF]

Autophagy Rep
Joaquim M, Dohrn MF, Chevrollier A, Escobar-Henriques M.   +3 more
europepmc   +1 more source