Results 91 to 100 of about 223,608 (200)
Deletion of Cardiac miR-17-92 Cluster Increases Ischemia/ Reperfusion Injury via PTEN Upregulation [PDF]
, 2017 The miR-17- 92 cluster is necessary for cell proliferation and development of the cardiovascular system. Deletion of this cluster leads to death in neonatal mice.
Prakash, Meeta B
core +1 more source
DNA methylation of selected tumor suppressor genes in endometrial hyperplasia
Biomedical PapersAims. To investigate DNA methylation of specific gene promoters in endometrial hyperplasia compared to normal endometrial tissue. Materials and Methods.
Ondrej Dvorak +4 more
doaj +1 more source
MiR-301a Promotes Cell Proliferation by Repressing PTEN in Renal Cell Carcinoma
Cancer Management and Research, 2020 Jun Li,1,* Donggen Jiang,1,* Qian Zhang,2,* Shubin Peng,3 Guolong Liao,1 Xiangwei Yang,1 Jiani Tang,1 Haiyun Xiong,1 Jun Pang1 1Department of Urology, Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, People’s Republic of China;
Li J +8 more
doaj
Cancer Management and Research, 2020 Xiao-Yu Su,1 Qian Zhao,1 Jin-Ming Ke,2 De-Hong Wu,1 Xin Zhu,1 Jiang Lin,1 Zhao-Qun Deng1 1Laboratory Center, The Affiliated People’s Hospital of Jiangsu University, Zhenjiang, Jiangsu, People’s Republic of China; 2Faculty of Forestry ...
Su XY +6 more
doaj
A PTEN translational isoform has PTEN-like activity.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2015 To identify PTEN isoform and explore its potential role in tumor suppression.Western blotting, over-expression, shRNA mediated knocking-down, and bioinformatic analysis were used to identify PTEN isoform and test its effect on PI3K-Akt signaling pathway.
Xie, Zhang +4 more
openaire +1 more source
Tumor suppressor genes in the tumor microenvironment
Disease Models & MechanismsBahareh Tabanifar +2 more
doaj +1 more source
J. Hepatol., 2015 BACKGROUND AIMS: PTEN is a dual lipid/protein phosphatase downregulated in steatotic livers with obesity or HCV infection. Liver specific PTEN knockout (LPTEN KO) mice develop steatosis inflammation/fibrosis and hepatocellular carcinoma with aging but surprisingly also enhanced glucose tolerance.
openaire +1 more source
Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR
Disease Models & Mechanisms, 2023 Nefeli Skoufou-Papoutsaki +11 more
doaj +1 more source
PTEN enhances the radiosensitivity of melanoma by inhibiting DNA-PKcs. [PDF]
Front Cell Dev BiolZhu S, Xu H, Shen F, Chen F, Wang Y.
europepmc +1 more source