Results 121 to 130 of about 147,647 (257)

ERα Agonist Protects Aged Female Mice From Sevoflurane Neurotoxicity via PTEN Nuclear Translocation. [PDF]

CNS Neurosci Ther
Zhang X, Lei Y, Gong B, Xu Y, Li D, Yu Y, Li F, Luo J.   +7 more
europepmc   +1 more source

SARS-CoV-2 ORF3a suppresses host antiviral interferon responses by promoting STUB1-mediated PTEN proteasomal degradation. [PDF]

J Virol
Fan L, Gao X, Feng W, Huang Q, Wei X, Yang C, Wu Y, Shen X, Zhao J, Zhou Y, Zhang Z.   +10 more
europepmc   +1 more source

A green solvent processable, self‐doped N‐annulated perylene butyl tetraester applied as a solar cell cathode interlayer

Polymer International, EarlyView.
A new organic molecular cathode interlayer is presented built upon the perylene butyl tetraester scaffold. The new molecule incorporates N‐annulation and a functional amine group to control optical, electrochemical and physical properties and delivers excellent solar cell performance. Abstract We report a new amino‐bay‐substituted, N‐annulated perylene
Kathryn M Wolfe, Shahidul Alam, Zachary T Gardner, Biswajit Pal, Alexander Harrison, Frédéric Laquai, Chad Risko, Gregory C Welch   +7 more
wiley   +1 more source

Clonal Evolution of Endometriosis to Peritoneal Endometrioid Carcinoma via <i>PTEN</i> Biallelic Inactivation: A Case Report With Integrated Genomic and Pathological Profiling. [PDF]

JCO Precis Oncol
Shibata T, Takata E, Shioya A, Yamada S, Ura H, Niida Y, Yasumoto K, Takakura M.   +7 more
europepmc   +1 more source

Molecular and genomic advances in breast cancer: A comprehensive review of predictive and therapeutic innovations

Precision Medical Sciences, EarlyView.
Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik, Arif Malik, Shahzad Ahmad, Hassan Mohsin, Shazia Iqbal   +4 more
wiley   +1 more source

LncRNA NORAD Promotes Spinal Cord Injury via miR-22-3p/PTEN Axis to Regulate Oxidative Stress and Inflammation in Neuronal Cells. [PDF]

Global Spine J
Zhang C, Chen L, Pan Y, Yu S, Wang Q, Chen Y, Xu H, Zhang Y.   +7 more
europepmc   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Neferine inhibits vascular smooth muscle cell proliferation and migration in atherosclerosis by targeting CYS130 and PHE252 in PTEN. [PDF]

Front Pharmacol
Jin Q, Liu Q, Ruan C, Xie Z, Gao X, Jiang Y, Jiang F, Xie B.   +7 more
europepmc   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan, Reyhaneh Farghadani, Ammu K. Radhakrishnan   +2 more
wiley   +1 more source

Dual PARP/Tankyrase Inhibition Enhances Antitumor Efficacy in PTEN-Deficient Endometrial Cancer. [PDF]

J Cell Mol Med
Kang SW, Eum H, Lee JY, Lee MS, Kim YM, Kim TW, Lee SW.   +6 more
europepmc   +1 more source