Results 231 to 240 of about 147,647 (257)
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PTEN: An Intercellular Peacekeeper?
Science Signaling, 2012Transfer of PTEN between cells has potential as an intercellular form of tumor suppression.
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Protecting PTEN in the Nucleus
Cancer Discovery, 2017Abstract A recent study shows that the transport receptor Importin-11 relocates PTEN, a tumor suppressor, to the nucleus, preventing its degradation in the cytoplasm. Mice lacking Importin-11 are prone to lung cancers, and its absence in human prostate and lung tumors signals a poorer prognosis.
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The Clinical Spectrum of PTEN Mutations
Annual Review of Medicine, 2020Lamis Yehia, Charis Eng
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Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma
Cancer Cell, 2019Peiwen Chen, Di Zhao, Jiexi Li
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The functions and regulation of the PTEN tumour suppressor: new modes and prospects
Nature Reviews Molecular Cell Biology, 2018Yu-Ru Lee +2 more
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