Results 251 to 260 of about 224,722 (300)

A novel PTEN variant causing hemimegalencephaly and focal nodular heterotopias in the developing human brain. [PDF]

open access: yesEpilepsia
Fazekas F   +16 more
europepmc   +1 more source

TPTE, a testis-specific PTEN family member, drives spermatogenesis via PI(4,5)P<sub>2</sub> synthesis. [PDF]

open access: yesCell Death Dis
Chen X   +14 more
europepmc   +1 more source
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PTEN in Immunity

2022
The tumor suppressor PTEN (Phosphatase and Tensin homolog deleted on Chromosome 10) executes critical biological functions that limit cellular growth and proliferation. PTEN inhibits activation of the proto-oncogenic PI3K pathway and is required during embryogenesis and to suppress tumor formation and cancer progression throughout life.
Antonella, Papa, Pier Paolo, Pandolfi
openaire   +2 more sources

PTEN surprise [PDF]

open access: yesNature Reviews Cancer, 2013
Sarah E Seton-Rogers
exaly   +2 more sources

PTEN Nuclear Functions

Cold Spring Harbor Perspectives in Medicine, 2019
For years, clinical and basic researchers have been aware of the presence of PTEN in the nucleus in cell culture, animal models, and both healthy and diseased human tissues. Despite the early recognition of nuclear PTEN, the understanding of the mechanisms of its nuclear localization, function in the nucleus, and importance in biology and human disease
Jason, Ho   +3 more
openaire   +2 more sources

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