Results 251 to 260 of about 224,722 (300)
A novel PTEN variant causing hemimegalencephaly and focal nodular heterotopias in the developing human brain. [PDF]
Fazekas F +16 more
europepmc +1 more source
Mechanisms by Which miR-584-5p Regulates Osteogenic Differentiation and Inflammation in Human Dental Pulp Stem Cells. [PDF]
Zou Y, Qin H, Chen F, Dong J.
europepmc +1 more source
FTO-dependent m<sup>6</sup>A Demethylation Activates Mxd1 To Enhance Vitamin D-induced Suppression of Neuroinflammation Via PTEN/AKT/PGC-1α Signaling Pathways in Microglia. [PDF]
Hu Z +9 more
europepmc +1 more source
Epigenomic excision for proteus nevus lipomatosis, rare PTEN overgrowth, and robotic debulking. [PDF]
Auns M, Muazzam DA, Sajid H, Mahato RK.
europepmc +1 more source
TPTE, a testis-specific PTEN family member, drives spermatogenesis via PI(4,5)P<sub>2</sub> synthesis. [PDF]
Chen X +14 more
europepmc +1 more source
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2022
The tumor suppressor PTEN (Phosphatase and Tensin homolog deleted on Chromosome 10) executes critical biological functions that limit cellular growth and proliferation. PTEN inhibits activation of the proto-oncogenic PI3K pathway and is required during embryogenesis and to suppress tumor formation and cancer progression throughout life.
Antonella, Papa, Pier Paolo, Pandolfi
openaire +2 more sources
The tumor suppressor PTEN (Phosphatase and Tensin homolog deleted on Chromosome 10) executes critical biological functions that limit cellular growth and proliferation. PTEN inhibits activation of the proto-oncogenic PI3K pathway and is required during embryogenesis and to suppress tumor formation and cancer progression throughout life.
Antonella, Papa, Pier Paolo, Pandolfi
openaire +2 more sources
Cold Spring Harbor Perspectives in Medicine, 2019
For years, clinical and basic researchers have been aware of the presence of PTEN in the nucleus in cell culture, animal models, and both healthy and diseased human tissues. Despite the early recognition of nuclear PTEN, the understanding of the mechanisms of its nuclear localization, function in the nucleus, and importance in biology and human disease
Jason, Ho +3 more
openaire +2 more sources
For years, clinical and basic researchers have been aware of the presence of PTEN in the nucleus in cell culture, animal models, and both healthy and diseased human tissues. Despite the early recognition of nuclear PTEN, the understanding of the mechanisms of its nuclear localization, function in the nucleus, and importance in biology and human disease
Jason, Ho +3 more
openaire +2 more sources

