Results 1 to 10 of about 196 (49)

Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAF^V600E

Pharmaceuticals, 2023
The investigation of novel EGFR and BRAFV600E dual inhibitors is intended to serve as targeted cancer treatment. Two sets of purine/pteridine-based derivatives were designed and synthesized as EGFR/BRAFV600E dual inhibitors. The majority of the compounds
Samar A. El-Kalyoubi, Hesham A. M. Gomaa, Elshimaa M. N. Abdelhafez, Mohamed Ramadan, Fatimah Agili, Bahaa G. M. Youssif   +5 more
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Time Flies—Age Grading of Adult Flies for the Estimation of the Post-Mortem Interval

Diagnostics, 2021
The estimation of the minimum time since death is one of the main applications of forensic entomology. This can be done by calculating the age of the immature stage of necrophagous flies developing on the corpse, which is confined to approximately 2–4 ...
Jens Amendt, Valentina Bugelli, Victoria Bernhardt   +2 more
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Directed search for diuretics among 6-substituted pteridine-2,4,7(1H,3H,8H)-triones

Medičnì Perspektivi, 2022
Directed search for biologically active compounds among heterocycles still remains a relevant area of medical chemistry. Among the significant number of heterocyclic compounds, pteridines deserve special attention.
K.V. Sokolova, V.V. Stavytskyi, S.I. Kovalenko, O.A. Podpletnya   +3 more
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Analysis of the Influence of Changing and Fixed Temperatures on the Growth and Pteridine Content in the Head of Adults Sarcophaga crassipalpis (Diptera: Sarcophagidae)

Animals, 2023
Flesh flies (Diptera: Sarcophagidae) are regarded as significant in medical and veterinary entomology, and their development models can be utilized as considerable markers to ascertain the minimum postmortem interval (PMImin).
Fernand Jocelin Ngando, Xiangyan Zhang, Hongke Qu, Changquan Zhang, Fengqin Yang, Yakai Feng, Yanjie Shang, Sile Chen, Lipin Ren, Yadong Guo   +9 more
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Crystal structure of (2-amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)zinc trihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, [Zn(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral coordination ...
Siddhartha S. Baisya, Baidyanath Ghosh, Parag S. Roy   +2 more
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ITRAQ Proteomic Analysis of Yellow and Black Skin in Jinbian Carp (Cyprinus carpio)

Life, 2020
Colors are important phenotypic traits for fitness under natural conditions in vertebrates. Previous studies have reported several functional genes and genetic variations of pigmentation, but the formation mechanisms of various skin coloration remained ...
Xiangchen Ye, Lingling Zhou, Jingyi Jia, Lingjing Wei, Yanhong Wen, Xueyu Yan, Jie Huang, Baojiang Gan, Kang Liu, Yejian Lv, Guangfu Hu   +10 more
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Crystal structure of 2,4-diamino-7-(hydroxymethyl)pteridin-1-ium nitrate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the crystal of the title molecular salt, C7H9N6O+·NO3−, the cations and anions are linked via N—H...O and O—H...O hydrogen bonds, forming sheets parallel to (100). Within the sheets there are numerous hydrogen-bonding ring motifs.
Palaniyappan Sivajeyanthi, Kasthuri Balasubramani, Muthaiah Jeevaraj, Kaliyaperumal Thanigaimani, Nuridayanti Che Khalib, Ibrahim Abdul Razak   +5 more
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The Sequence of Mouse Dihydropteridine Reductase cDNA, and Comparison with Human and Rat Sequences

Pteridines, 1996
A mouse liver eDNA library in λZAP was screened using a 627 bp portion of 32p randomly labeled human dihydropteridine reductase (731 bp) cDNA and seven positive clones were obtained.
Yang Nan, Hanssen Kevin, Armarego Wilfred L.F.   +2 more
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Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin

Pteridines, 2002
In the vasculature, a physiologic production of nitric oxide (NO) is maintained by endothelial nitric oxide synthase (eNOS). Induction of inducible nitric oxide synthase (ÍNOS) under inflammatory conditions (e.g. septic shock) resulting in high levels of
Mueller Nicolas J, Walter Roland Β, Linscheid Philippe, Schaffner Andreas, Schoedon Gabriele   +4 more
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1H-Benzo[g]pteridine-2,4-dione

IUCrData, 2023
The structure of the title compound, C10H6N4O2, reported by Smalley et al. [(2021). Cryst. Growth Des. 22, 524–534] from powder diffraction data and 15N NMR spectroscopy, is confirmed using low-temperature data from a twinned crystal. The tautomer in the
Rao M. Uppu, Frank R. Fronczek
doaj   +1 more source