Results 1 to 10 of about 10,390 (256)

Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii [PDF]

, 1982
Background: The proteins of halophilic archaea require high salt concentrations both for stability and for activity, whereas they denature at low ionic strength. The structural basis for this phenomenon is not yet well understood.
Pieper, Ursula, Kapadia, Geeta, Mevarech, Moshe, Herzberg, Osnat   +3 more
core   +5 more sources

Being red, blue and green: the genetic basis of coloration differences in the strawberry poison frog (Oophaga pumilio)

BMC Genomics, 2020
Background Animal coloration is usually an adaptive attribute, under strong local selection pressures and often diversified among species or populations.
Ariel Rodríguez, Nicholas I. Mundy, Roberto Ibáñez, Heike Pröhl   +3 more
doaj   +1 more source

Development and validation of chromatographic methods to study folate derivatives produced by yeasts [PDF]

, 2007
Folate, or folic acid, is an important water soluble B vitamin that exists in many different forms. Its presence is necessary for synthesis of DNA and RNA and methylation of homocysteine to methionine.
Patring, Johan
core  

Folate polyglutamylation is required for rice seed development [PDF]

, 2010
In plants, polyglutamylated folate forms account for a significant proportion of the total folate pool. Polyglutamylated folate forms are produced by the enzyme folylpolyglutamate synthetase (FPGS).
A Wingler, AD Hanson, AD Hanson, Anahi Santoyo Castelazo, Anne Diévart, B Gambonnet, B Shane, BA Moffatt, BF Lin, BF Lin, CR Somerville, D Heineke, David A. Barrett, Delphine Mieulet, E Cossins, Emmanuel Guiderdoni, G Orsomando, GJ Basset, GJ Basset, GJ Basset, Gregory Tucker, H Bauwe, H Imeson, Helen Parker, I Hayashi, JR Suh, K Gallardo, KR Lowe, L Chen, L DeSouza, LC Garratt, Malcolm J. Bennett, ML Jones, Nadège Lanau, Nampeung Anukul, O Galivan, PA Counce, Payam Mehrshahi, R Díaz de la Garza, Riza Abilgos Ramos, S Jabrin, S Ravanel, S Ravanel, S Storozhenko, V Besson, X Sun, Y Wang   +46 more
core   +2 more sources

Sepiapterin reductase (Spra and Sprb) regulate carotenoid and pteridine metabolism influencing the koi carp (Cyprinus carpio L.) coloration

Aquaculture Reports
The evolution of teleost coloration is strongly linked with the fish-specific genome duplication (FSGD). Sepiapterin reductase (Spr) is commonly required in pteridine pigment synthesis and two paralogs are found in teleosts.
X. Tian, Y.S. Shan, N.N. Peng, X. Ma, X. Shi, H. Li, X.J. Li, X.L. Meng   +7 more
doaj   +1 more source

Chemical structure of 1-O-(L-erythro-biopterin-2'-yl)-a-glucose isolated from a cyanobacterium Synechococcus sp. PCC 7942

Pteridines, 2001
A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee, Hwang Yoon Kyung, Kang Yong Han, Park Young Shik   +3 more
doaj   +1 more source

First Synthesis of a Natural Isoxanthopterin Glycoside, Asperopterin-A [PDF]

, 2012
The key precursor, N-2-(N,N-dimethylaminomethylene)-6-hydroxymethy1-8-methyl-3[2-(4-nitrophenypethyl]-7-xanthopterin (9) was efficiently prepared from 2,5-diamino-6-methylam1no-3H-pyrimidin-4-one (3) and ethyl 3-(tert-butyldimethylsilyloxy)-2 ...
Ejiri, Kazumasa, Hanaya, Tadashi, Yamamoto, Hiroshi   +2 more
core   +1 more source

The role of urinary pteridines as disease biomarkers

Pteridines, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj   +1 more source

Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs [PDF]

, 2016
Flavonoids represent a potential source of new antitrypanosomatidic leads. Starting from a library of natural products, we combined target-based screening on pteridine reductase 1 with phenotypic screening on Trypanosoma brucei for hit identification ...
Anabela Cordeiro-da-Silva, Annalisa Tait, Bernhard Ellinger, Bifeld E., Birte Behrens, Catarina Baptista, Cecilia Pozzi, Chiara Borsari, Eugenia Bifeld, Federica Pellati, Flavio Di Pisa, Gesa Witt, Giacomo Landi, Ina Poehner, Jeanette Reinshagen, Joachim Clos, José M Alunda, Juan Torrado, Julia Eick, Luca Costantino, Lucia Dello Iacono, Manfred Kohler, Maria Kuzikov, Maria Paola Costi, Markus Wolf, María D. Jiménez-Antón, María J. Corral, Matteo Trande, Nuno Santarem, Oliver Keminer, Paloma Tejera Nevado, Philip Gribbon, Rebecca C. Wade, Rosaria Luciani, Sereno D., Sheraz Gul, Stefan Henrich, Stefania Ferrari, Stefano Mangani   +38 more
core   +30 more sources

Structure and dynamics of pteridine reductase 1: the key phenomena relevant to enzyme function and drug design [PDF]

, 2023
Joanna Panecka-Hofman, Ina Poehner
openalex   +1 more source