Results 1 to 10 of about 13,736 (293)
Pharmaceuticals, 2023 The investigation of novel EGFR and BRAFV600E dual inhibitors is intended to serve as targeted cancer treatment. Two sets of purine/pteridine-based derivatives were designed and synthesized as EGFR/BRAFV600E dual inhibitors. The majority of the compounds
Samar A. El-Kalyoubi +5 more
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Crystal structure of 2,4-diamino-7-(hydroxymethyl)pteridin-1-ium nitrate [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the crystal of the title molecular salt, C7H9N6O+·NO3−, the cations and anions are linked via N—H...O and O—H...O hydrogen bonds, forming sheets parallel to (100). Within the sheets there are numerous hydrogen-bonding ring motifs.
Palaniyappan Sivajeyanthi +5 more
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Analysis of the Influence of Changing and Fixed Temperatures on the Growth and Pteridine Content in the Head of Adults Sarcophaga crassipalpis (Diptera: Sarcophagidae) [PDF]
Animals, 2023 Flesh flies (Diptera: Sarcophagidae) are regarded as significant in medical and veterinary entomology, and their development models can be utilized as considerable markers to ascertain the minimum postmortem interval (PMImin).
Fernand Jocelin Ngando +9 more
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A New Synthesis of Pteridines [PDF]
Nature, 1949 THERE is a growing biological interest in derivatives of pteridine (I: R1, R2, R3, R4 = H) as a source of antagonists for folic acid (I: R1 = OH; R2 = NH2 ; R4 = H; R3 = CH2.NH.C6H4.CO.NHCH(COOH): CH2CH2COOH-p), since this vitamin plays an important part in the growth of certain bacteria and normal and malignant tissue.
G. M. Timmis
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Serum Neopterin, Biopterin, Tryptophan, and Kynurenine Levels in Patients with Fabry Disease [PDF]
Balkan Medical JournalBackground: Fabry disease is characterized by the accumulation of globotriaosylceramide. Substrate accumulation in lysosomes is thought to trigger an inflammatory response and is responsible for progressive organ damage through the induction of ...
Tuğçe Uçar +7 more
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Pteridines and Lipid Metabolism [PDF]
Pteridines, 1998 Summary The effect of 9 different pteridines on fatty acid incorporation into phospholipids as well as on cholesterol and phospholipid content was compared in vitro using rat liver homogenate, Krebs-Ringer phosphate buffer containing 0.3 % albumin (pH=7.4), fatty acid mixture and glycerol.
Vera Rudzite +5 more
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Biosynthesis of Pteridines in Insects: A Review. [PDF]
InsectsPteridines are important cofactors for many biological functions of all living organisms, and they were first discovered as pigments of insects, mainly in butterfly wings and the eye and body colors of insects. Most of the information on their structures and biosynthesis has been obtained from studies with the model insects Drosophila melanogaster and ...
Ferré J.
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Chemischer Informationsdienst, 1981 AbstractDie Uracilderivate (I) und (IV) reagieren mit Acetylendicarbonsäuredimethylester (II) zum Bis‐methoxycarbonyl‐dimethyl‐lumazin (III).
K. SENGA +9 more
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Pteridines, XCVI. Synthesis and Reactions of 6-(1,2,3-Trihydroxypropyl)pteridines
Pteridines, 1990 Various hydropyrano [3.2-g] pteridines (7, 10, 12, 21 , 33) were oxidized to the corresponding 6-(1,2,3- trihydroxypropyl)pteridine derivatives (8,9, 11, 13,32, 34), which are valuable intermediates for the synthesis of new 6-substituted pteridines (15 -
Soyka Rainer, Pfleiderer Wolfgang
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Time Flies—Age Grading of Adult Flies for the Estimation of the Post-Mortem Interval
Diagnostics, 2021 The estimation of the minimum time since death is one of the main applications of forensic entomology. This can be done by calculating the age of the immature stage of necrophagous flies developing on the corpse, which is confined to approximately 2–4 ...
Jens Amendt +2 more
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