Results 91 to 100 of about 10,390 (256)

Pteridines, XCVI. Synthesis and Reactions of 6-(1,2,3-Trihydroxypropyl)pteridines

Pteridines, 1990
Various hydropyrano [3.2-g] pteridines (7, 10, 12, 21 , 33) were oxidized to the corresponding 6-(1,2,3- trihydroxypropyl)pteridine derivatives (8,9, 11, 13,32, 34), which are valuable intermediates for the synthesis of new 6-substituted pteridines (15 -
Soyka Rainer, Pfleiderer Wolfgang
doaj   +1 more source

(2-Amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)cobalt(II) trihydrate

Acta Crystallographica Section E, 2013
In the title compound, [Co(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral geometry ...
Siddhartha S. Baisya, Samir Sen, Parag S. Roy   +2 more
doaj   +1 more source

Preparation and characterization of a tumor-targeting dual-image system based on iron oxide nanoparticles functionalized with folic acid and rhodamine [PDF]

, 2017
Cancer is one of the diseases with most deaths worldwide, around 8.2 million annually. For this reason, several treatments and diagnostic tools have been investigated and developed over the past decades. Among them, a dual-image system has been developed
ANCIRA CORTEZ, ALEJANDRA, ANCIRA CORTEZ, ALEJANDRA, Cuevas Yáñez, Erick, Cuevas Yáñez, Erick, GONZALEZ ROMERO, CARLOS, GONZALEZ ROMERO, CARLOS, LOPEZ TELLEZ, GUSTAVO, LOPEZ TELLEZ, GUSTAVO, MEDINA VELAZQUEZ, LUIS ALBERTO, MEDINA VELAZQUEZ, LUIS ALBERTO, MORALES AVILA, ENRIQUE, MORALES AVILA, ENRIQUE, OCAMPO GARCIA, BLANCA ELI, OCAMPO GARCIA, BLANCA ELI   +13 more
core   +3 more sources

Synthesis of 7-Acyl-2,4-disubstituted Pteridines by Radical Nucleophilic Substitution and Displacement Reactions

Pteridines, 2004
2,4-Disubstituted pteridine derivatives (1-3) react with acyl radicals very selectively in position 7 by a nucleophilic Substitution mechanism (4-10).
Döring Thomas, Boruah Romesh C., Pfleiderer Wolfgang   +2 more
doaj   +1 more source

Transcriptome Analysis Reveals That Alfalfa Promotes Rumen Development Through Enhanced Metabolic Processes and Calcium Transduction in Hu Lambs

Frontiers in Genetics, 2019
A healthy gut is very important for young animal development. The rumen of ruminants expands in size with the colonization of microbiota by 2 months of age. This process is promoted by alfalfa intervention.
Bin Yang, Hongwei Chen, Jiawen Cao, Bo He, Shanshan Wang, Yang Luo, Jiakun Wang   +6 more
doaj   +1 more source

Black and White: Structural and Functional Aspects of Dermal Chromatophores of the Marbled Whiptail Lizard (Cnemidophorus Marmoratus) [PDF]

, 2004
The skin of reptiles is a complex organ with many sensory, regulatory and behavioral functions. Desert reptiles face a suite of challenges as their skin contacts hot-dry environmental surfaces.
Swan, James
core   +1 more source

SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor Growth in Vivo by inducing G2/M cell cycle arrest [PDF]

, 2015
Protein kinase D (PKD) has been implicated in many aspects of tumorigenesis and progression, and is an emerging molecular target for the development of anticancer therapy.
Carder, EJ, Deng, F, Farber, E, Salamoun, JM, Tandon, M, Tang, H, Wang, QJ, Wipf, P, Xu, S   +8 more
core   +3 more sources

In vitro Mutagenesis of Human Dihydropteridine Reductase at the Active Site and at Altered Sites Found in the Reductases of Deficient Children

Pteridines, 1996
A general procedure for in vitro site-directed mutagenesis of the wild-type dihydropteridine reductase gene has been used successfully to make eight mutant proteins.
Zhang Hong-Ping, Yang Nan, Armarego Wilfred L. F.   +2 more
doaj   +1 more source

Fish and shellfish diseases in culture systems IX Screening of bacteria for identification [PDF]

, 1982
Taxonomy is a significant aspect -of study, for a microbiologist, in any application. But, the problems are greater for an aquatic microbiologist as compared to those of a medical microbiologist, because studies have been made in depth in medical ...
Pillai, C Thankappan
core  

Antitumor studies. Part 1: Design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents [PDF]

, 2006
Novel 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides were prepared as a new class of antitumor agents and showed significant antitumor activities against NCI-H 460, HCT 116, A 431, CCRF-HSB-2, and KB cell lines. In vivo investigation,
Akaho, Eiichi, Ali, Hamed I.., Ashida, Noriyuki, Hayakawa, Hiroyuki, Ikeya, Hisao, Kambara, Hiroto, Kawashima, Yutaka, Miura, Shinji, Nagamatsu, Tomohisa, Tomita, Keiichiro, Yamagishi, Takehiro, Yoneda, Fumio   +11 more
core   +1 more source