Results 101 to 110 of about 13,736 (293)

Reaction of Pteridine and Its 8-0xide with Grignard Reagents, Regioselective 7-Alkylation of Pteridine

Pteridines, 1995
Reaction of 2-amino-4-butoxypteridine (1) with alkyl- or phenylmagnesium bromide followed by protonative and oxidative work-up with a solution of iodine in acetic acid gives 7 -alkyl- or 7 -phenylpteridines (2 ).
Kiguchi Kenji, Murata Shizuaki, Sugimoto Takashi   +2 more
doaj   +1 more source

Gene expression in Leishmania is regulated predominantly by gene dosage [PDF]

, 2017
Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here,
Berriman, Matthew, Beverley, Stephen M., Cotton, James A., Durrant, Caroline, Grigg, Michael E., Iantorno, Stefano A., Khan, Asis, Myler, Peter, Ouellette, Marc, Sacks, David L., Sanders, Mandy J., Warren, Wesley C., Weiss, Louis M.   +12 more
core   +3 more sources

Studies and Comparison of Urinary Pteridine Patterns in Dogs and Cats and their Alteration in Various Neoplasias and Virus Infections

Pteridines, 1989
Urinary excretion levels of five pteridines in healthy cats and dogs and in 14 groups of animals with tumours or virus infections were determined by HPLC after partial purification by ion exchange chromatography.
Goldberg M., Gassner F., Merkenschlager M.   +2 more
doaj   +1 more source

Synthesis of 7-Acyl-2,4-disubstituted Pteridines by Radical Nucleophilic Substitution and Displacement Reactions

Pteridines, 2004
2,4-Disubstituted pteridine derivatives (1-3) react with acyl radicals very selectively in position 7 by a nucleophilic Substitution mechanism (4-10).
Döring Thomas, Boruah Romesh C., Pfleiderer Wolfgang   +2 more
doaj   +1 more source

(2-Amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)cobalt(II) trihydrate

Acta Crystallographica Section E, 2013
In the title compound, [Co(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral geometry ...
Siddhartha S. Baisya, Samir Sen, Parag S. Roy   +2 more
doaj   +1 more source

Analoghi chinossalinici omologhi del thymitaq e 2-(ariltio)chinossaline analoghe del trimetrexato e del metotrexato [PDF]

, 2002
Abbiamo progettato una nuove serie di chinossaline le quali possono comportarsi come bioisosteri delle pteridine e delle chinazoline dotate di attività antifolica, apparse recentemente in ...
Costi, M. Paola, La Colla, Paolo, Loriga, Mario, Marongiu, L., Marturana, Flavia, Paglietti, Giuseppe, Venturelli, Alberto, Vitale, Gabriella   +7 more
core  

Folate polyglutamylation is required for rice seed development [PDF]

, 2010
In plants, polyglutamylated folate forms account for a significant proportion of the total folate pool. Polyglutamylated folate forms are produced by the enzyme folylpolyglutamate synthetase (FPGS).
A Wingler, AD Hanson, AD Hanson, Anahi Santoyo Castelazo, Anne Diévart, B Gambonnet, B Shane, BA Moffatt, BF Lin, BF Lin, CR Somerville, D Heineke, David A. Barrett, Delphine Mieulet, E Cossins, Emmanuel Guiderdoni, G Orsomando, GJ Basset, GJ Basset, GJ Basset, Gregory Tucker, H Bauwe, H Imeson, Helen Parker, I Hayashi, JR Suh, K Gallardo, KR Lowe, L Chen, L DeSouza, LC Garratt, Malcolm J. Bennett, ML Jones, Nadège Lanau, Nampeung Anukul, O Galivan, PA Counce, Payam Mehrshahi, R Díaz de la Garza, Riza Abilgos Ramos, S Jabrin, S Ravanel, S Ravanel, S Storozhenko, V Besson, X Sun, Y Wang   +46 more
core   +2 more sources

Transcriptome Analysis Reveals That Alfalfa Promotes Rumen Development Through Enhanced Metabolic Processes and Calcium Transduction in Hu Lambs

Frontiers in Genetics, 2019
A healthy gut is very important for young animal development. The rumen of ruminants expands in size with the colonization of microbiota by 2 months of age. This process is promoted by alfalfa intervention.
Bin Yang, Hongwei Chen, Jiawen Cao, Bo He, Shanshan Wang, Yang Luo, Jiakun Wang   +6 more
doaj   +1 more source

An Efficient Synthesis of 2'-O-(β-D-Ribofuranosyl)biopterin [PDF]

, 2008
N(2)-(N,N-Dimethylaminomethylene)-3-[2-(4-nitrophenyl)ethyl]-1',2'-di-O (trimethylsilyl)biopterin (4) was prepared from biopterin (1a, 86% overall yield) in 5 steps. Glycosylation of 4 with 1,2,3,5-tetra-O-acetyl-β D-ribofuranose (5a) and its 2,3,5-tri-O-
Fujita, Hiroshi, Hanaya, Tadashi, Pfleiderer, Wolfgang, Soranaka, Kazuyuki, Torigoe, Kiyoshi, Yamamoto, Hiroshi   +5 more
core   +1 more source

Dissecting the Metabolic Roles of Pteridine Reductase 1 in Trypanosoma brucei and Leishmania major*

Journal of Biological Chemistry, 2011
Leishmania parasites are pteridine auxotrophs that use an NADPH-dependent pteridine reductase 1 (PTR1) and NADH-dependent quinonoid dihydropteridine reductase (QDPR) to salvage and maintain intracellular pools of tetrahydrobiopterin (H4B).
Han B. Ong, N. Sienkiewicz, S. Wyllie, A. Fairlamb   +3 more
semanticscholar   +1 more source