Antitumor studies. Part 1: Design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents [PDF]
Novel 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides were prepared as a new class of antitumor agents and showed significant antitumor activities against NCI-H 460, HCT 116, A 431, CCRF-HSB-2, and KB cell lines. In vivo investigation,
Akaho, Eiichi +11 more
core +1 more source
Metabolic Processes Preserved as Biosignatures in Iron-Oxidizing Microorganisms: Implications for Biosignature Detection on Mars [PDF]
Iron-oxidizing bacteria occupy a distinct environmental niche. These chemolithoautotrophic organisms require very little oxygen (when neutrophilic) or outcompete oxygen for access to Fe(II) (when acidophilic).
Emerson, David +3 more
core +1 more source
Corallistine, a new polynitrogen compound from the sponge Corallistes fulvodesmus L. and L. [PDF]
Two polynitrogen compounds 1-methyl-pteridine-2,4-dione 1b and corallistine 2 were isolated from the new-caledonian sponge #Corallistes fulvodesmus$ L. & L.
Cesario, M. +4 more
core
34th International Winter Workshop / Clinical, Chemical and Biochemical Aspects of Pteridines and Related Topics [PDF]
Melichar Palacký +26 more
openalex +1 more source
New Prenylated Indole Homodimeric and Pteridine Alkaloids from the Marine-Derived Fungus Aspergillus austroafricanus Y32-2 [PDF]
Peihai Li +7 more
openalex +1 more source
Background: Pteridine metabolic pathway is unusual features of Leishmania, which is necessary for the growth of parasite. Leishmania has evolved a complex and versatile pteridine salvage network which has the ability of scavenging a wide area of the ...
H Masjedi +10 more
doaj +2 more sources
Linkage of Pteridine Metabolism to Iron Homeostasis
Iron is an essential growth factor for the proliferation and differentiation of all living cells in being centrally involved in oxygen transport by hemoglobin and myoglobin, in electron transport during mitochondrial respiration as being a part of ...
Weiss Günter
doaj +1 more source
Structure of recombinantLeishmania donovanipteridine reductase reveals a disordered active site [PDF]
K.L. Barrack +4 more
openalex +1 more source

