Crystal structure of 2,4-diamino-7-(hydroxymethyl)pteridin-1-ium nitrate [PDF]
In the crystal of the title molecular salt, C7H9N6O+·NO3−, the cations and anions are linked via N—H...O and O—H...O hydrogen bonds, forming sheets parallel to (100). Within the sheets there are numerous hydrogen-bonding ring motifs.
Palaniyappan Sivajeyanthi +5 more
doaj +4 more sources
Dilute-and-Shoot-Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry for Pteridine Profiling in Human Urine and Its Association with Different Pathologies [PDF]
Pteridines are a group of compounds synthesised by many living organisms that are involved in the metabolism of many cofactors and vitamins. Their concentration in biological fluids may be altered by various pathologies such as cancer or inflammatory ...
Claudia Giménez-Campillo +7 more
doaj +2 more sources
Serum Neopterin, Biopterin, Tryptophan, and Kynurenine Levels in Patients with Fabry Disease [PDF]
Background: Fabry disease is characterized by the accumulation of globotriaosylceramide. Substrate accumulation in lysosomes is thought to trigger an inflammatory response and is responsible for progressive organ damage through the induction of ...
Tuğçe Uçar +7 more
doaj +2 more sources
SummaryA series of new amino acid-tetrahydropterin-conjugates has been synthesized starting from N 2-isobutyryl-6,7- dimethyl-5,6,7,8-tetrahydropterin (7). The amino acids have been attached in form of their esters (10 - 16) via a succinyl spacer to the N-5 position (17 - 23) or directly via the carboxyl function applying CBZprotected activated esters (
Ronan John Lockart, Wolfgang Pfleiderer
openalex +2 more sources
Pigments, Chromatophore Structure, and Gene Expression Underlying Colour Polytypy of a Panamanian Poison Frog. [PDF]
ABSTRACT Colour polytypism represents an example of phenotypic diversification shaped by genetic divergence and ecological pressures. Poison frogs of the genus Oophaga (Dendrobatidae) are highly polytypic in coloration, making them an ideal system for investigating the genetic and physiological basis of colour variation.
Mantzana-Oikonomaki V +7 more
europepmc +2 more sources
The investigation of novel EGFR and BRAFV600E dual inhibitors is intended to serve as targeted cancer treatment. Two sets of purine/pteridine-based derivatives were designed and synthesized as EGFR/BRAFV600E dual inhibitors. The majority of the compounds
Samar A. El-Kalyoubi +5 more
doaj +1 more source
A systematic review and meta-analysis of pteridines in mild cognitive impairment and Alzheimer's disease. [PDF]
Mangoni AA, Zinellu A.
europepmc +3 more sources
Time Flies—Age Grading of Adult Flies for the Estimation of the Post-Mortem Interval
The estimation of the minimum time since death is one of the main applications of forensic entomology. This can be done by calculating the age of the immature stage of necrophagous flies developing on the corpse, which is confined to approximately 2–4 ...
Jens Amendt +2 more
doaj +1 more source
The wing colours and patterns of the genus Zygaena are limited and mainly red and black. This fact creates problems to distinguish closely related species by visual inspection.
G. Bunetebarth, A. Nahirnic-Beshkova
doaj +1 more source
An Allele of Glutamate Formiminotransferase Triggers 5-Methyl-Tetrahydrofolate-to-MeFox Conversion and Facilitates Folate Biofortification in Maize. [PDF]
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Lian T +15 more
europepmc +2 more sources

