Results 21 to 30 of about 10,390 (256)

Series of Microporous Redox-Active Pillared Metal-Organic Frameworks Based On Alloxazine Ligands. [PDF]

open access: yesChemistryOpen
Two series of robust pillared metal–organic frameworks using a redoactive ligand based on alloxazine and transition metals have been evidenced by XRD. The compounds have high decomposition temperatures, and their sorption properties are measured, revealing relatively low surface areas and a moderate uptake of CO2 and C2H4 at high pressures.
Casas J   +5 more
europepmc   +2 more sources

Directed search for diuretics among 6-substituted pteridine-2,4,7(1H,3H,8H)-triones

open access: yesMedičnì Perspektivi, 2022
Directed search for biologically active compounds among heterocycles still remains a relevant area of medical chemistry. Among the significant number of heterocyclic compounds, pteridines deserve special attention.
K.V. Sokolova   +3 more
doaj   +1 more source

Structure-based design and synthesis of antiparasitic pyrrolopyrimidines targeting pteridine reductase 1 [PDF]

open access: yes, 2014
The treatment of Human African Trypanosomiasis remains a major unmet health need in sub-Saharan Africa. Approaches involving new molecular targets are important and pteridine reductase 1 (PTR1), an enzyme that reduces dihydrobiopterin in Trypanosoma spp.
Abedawn I. Khalaf   +41 more
core   +5 more sources

ITRAQ Proteomic Analysis of Yellow and Black Skin in Jinbian Carp (Cyprinus carpio)

open access: yesLife, 2020
Colors are important phenotypic traits for fitness under natural conditions in vertebrates. Previous studies have reported several functional genes and genetic variations of pigmentation, but the formation mechanisms of various skin coloration remained ...
Xiangchen Ye   +10 more
doaj   +1 more source

Analysis of the Influence of Changing and Fixed Temperatures on the Growth and Pteridine Content in the Head of Adults Sarcophaga crassipalpis (Diptera: Sarcophagidae)

open access: yesAnimals, 2023
Flesh flies (Diptera: Sarcophagidae) are regarded as significant in medical and veterinary entomology, and their development models can be utilized as considerable markers to ascertain the minimum postmortem interval (PMImin).
Fernand Jocelin Ngando   +9 more
doaj   +1 more source

Crystal structure of (2-amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)zinc trihydrate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, [Zn(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral coordination ...
Siddhartha S. Baisya   +2 more
doaj   +1 more source

Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes

open access: yesAtherosclerosis Plus, 2021
Background and aims: We have recently proposed urinary pteridine level as a useful biomarker of oxidative stress in a general population. However, the significance of urinary pteridines in patients with diabetes is unknown.
Mikio Marumo   +2 more
doaj   +1 more source

Antitumor studies. Part 4: Design, synthesis, antitumor activity, and molecular docking study of novel 2-substituted 2-deoxoflavin-5-oxides, 2-deoxoalloxazine-5-oxides, and their 5-deaza analogs [PDF]

open access: yes, 2008
Various novel 10-alkyl-2-deoxo-2-methylthioflavin-5-oxides and their 2-alkylamino derivatives were prepared by facile nitrosative cyclization of 6-(N-alkylanilino)-2-methylthiopyrimidin-4(3H)-ones followed by nucleophilic replacement of the 2-methylthio ...
Ali, Hamed I.   +2 more
core   +1 more source

Diversity oriented synthesis : substitution at C5 in unreactive pyrimidines by Claisen rearrangement and reactivity in nucleophilic substitution at C2 and C4 in pteridines and pyrido[2,3-d]pyrimidines [PDF]

open access: yes, 2011
Diversity oriented synthesis of fused pyrimidines leads to scaffolds with many biological activities. In the case of the preparation of pyrido[2,3-d]pyrimidines from 2-alkylthiopyrimidines, the formation of a new carbon-carbon bond at C5 is required, a ...
Adcock, Jonathan Paul   +3 more
core   +1 more source

The Sequence of Mouse Dihydropteridine Reductase cDNA, and Comparison with Human and Rat Sequences

open access: yesPteridines, 1996
A mouse liver eDNA library in λZAP was screened using a 627 bp portion of 32p randomly labeled human dihydropteridine reductase (731 bp) cDNA and seven positive clones were obtained.
Yang Nan   +2 more
doaj   +1 more source

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