Results 21 to 30 of about 196 (49)

Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes

Atherosclerosis Plus, 2021
Background and aims: We have recently proposed urinary pteridine level as a useful biomarker of oxidative stress in a general population. However, the significance of urinary pteridines in patients with diabetes is unknown.
Mikio Marumo, Kazumi Ekawa, Ichiro Wakabayashi   +2 more
doaj  

Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster

eLife, 2017
Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors.
Hyun Bong Park, Corey E Perez, Karl W Barber, Jesse Rinehart, Jason M Crawford   +4 more
doaj   +1 more source

1,3,7-Trimethyl-2,4-dioxo-1,2,3,4-tetrahydropteridine-6-carboxylic acid hemihydrate

Acta Crystallographica Section E, 2010
In the title compound, C10H10N4O4·0.5H2O, the two rings of the pteridine system are nearly coplanar [dihedral angle = 4.25 (9)°]. The atoms of the carboxyl group are also coplanar with the pteridine unit [r.m.s. deviation from
Miguel N. Moreno-Carretero, Fátima M. Linares-Ordóñez, Sonia B. Jiménez-Pulido, René Faure, Nuria A. Illán-Cabeza   +4 more
doaj   +1 more source

Urinary Oxidative Damage Markers and Their Association with Obesity-Related Metabolic Risk Factors

Antioxidants, 2022
Oxidative damage and inflammation are possible mechanisms linking obesity to diabetes and related complications. This study investigates the levels of oxidative damage markers in the urine of community free-living subjects with increased prevalence of ...
Salah Gariballa, Abderrahim Nemmar, Ozaz Elzaki, Nur Elena Zaaba, Javed Yasin   +4 more
doaj   +1 more source

Chemical structure of 1-O-(L-erythro-biopterin-2'-yl)-a-glucose isolated from a cyanobacterium Synechococcus sp. PCC 7942

Pteridines, 2001
A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee, Hwang Yoon Kyung, Kang Yong Han, Park Young Shik   +3 more
doaj   +1 more source

Being red, blue and green: the genetic basis of coloration differences in the strawberry poison frog (Oophaga pumilio)

BMC Genomics, 2020
Background Animal coloration is usually an adaptive attribute, under strong local selection pressures and often diversified among species or populations.
Ariel Rodríguez, Nicholas I. Mundy, Roberto Ibáñez, Heike Pröhl   +3 more
doaj   +1 more source

Dilute-and-Shoot-Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry for Pteridine Profiling in Human Urine and Its Association with Different Pathologies

Chemosensors, 2023
Pteridines are a group of compounds synthesised by many living organisms that are involved in the metabolism of many cofactors and vitamins. Their concentration in biological fluids may be altered by various pathologies such as cancer or inflammatory ...
Claudia Giménez-Campillo, Marta Pastor-Belda, Natalia Arroyo-Manzanares, Natalia Campillo, Blanca del Val Oliver, José Zarauz-García, Luis Sáenz, Pilar Viñas   +7 more
doaj   +1 more source

The role of urinary pteridines as disease biomarkers

Pteridines, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj   +1 more source

Serum Neopterin, Biopterin, Tryptophan, and Kynurenine Levels in Patients with Fabry Disease

Balkan Medical Journal
Background: Fabry disease is characterized by the accumulation of globotriaosylceramide. Substrate accumulation in lysosomes is thought to trigger an inflammatory response and is responsible for progressive organ damage through the induction of ...
Tuğçe Uçar, Mehmet Şerif Cansever, Esra Isat, Tanyel Zubarioğlu, Ayşe Çiğdem Aktuğlu Zeybek, Birol Topçu, Nurhan Seyahi, Ertuğrul Kıykım   +7 more
doaj   +1 more source

Early Diagnosis of 6-Pyruvoyl-tetrahydropterin Synthase Deficiency

Pteridines, 1994
6-Pyruvoyl-tetrahydropterin synthase (PTPS) deficiency, which used to be called dihydrobiopterin synthase deficiency, is the most common kind of tetrahydrobiopterin deficiency. Early treatment by administration of tetrahydrobiopterin and neurotransmitter
Shintaku Haruo
doaj   +1 more source