Results 31 to 40 of about 196 (49)

Pteridines, IXC. Synthesis, Oxidations and Reactions of 6- and 7-Hydroxy-2-thiolumazines Selective Cytotoxicity of Carboxypeptidase-activated Methotrexate ex-Peptides

Pteridines, 1989
Various 6-(10, 11) and 7-hydroxy-2-thiolumazines (8,9) have been synthesized and oxidations of the thioamide function studied . H20 2 Oxidation of 7-hydroxy-2-thiolumazine (8) in basic medium leads to pteridine-4,7- dione-2-sulfinate (12), which ...
Bartke Michael, Pfleiderer Wolfgang
doaj   +1 more source

A single gene (yes) controls pigmentation of eyes and scales in Heliothis virescens

Journal of Insect Science, 2001
A yellow-eyed mutant was discovered in a strain of Heliothis virescens, the tobacco budworm, that already exhibited a mutation for yellow scale, y. We investigated the inheritance of these visible mutations as candidate markers for transgenesis.
Thomas M. Brown, Sae-Youll Cho, Sujin Park, Satish S. Pimprale, Patricia K. Bryson   +4 more
doaj  

Widespread occurrence of glyceryl ether monooxygenase activity in rat tissues detected by a novel assay

Journal of Lipid Research, 2007
An assay was set up for glyceryl ether monooxygenase activity in tissue samples using the novel substrate 1-O-pyrenedecyl-sn-glycerol and high-performance liquid chromatographic analysis of reaction mixtures with fluorescence detection, allowing robust ...
Ernst R. Werner, Albin Hermetter, Helmut Prast, Georg Golderer, Gabriele Werner-Felmayer   +4 more
doaj  

Studies and Comparison of Urinary Pteridine Patterns in Dogs and Cats and their Alteration in Various Neoplasias and Virus Infections

Pteridines, 1989
Urinary excretion levels of five pteridines in healthy cats and dogs and in 14 groups of animals with tumours or virus infections were determined by HPLC after partial purification by ion exchange chromatography.
Goldberg M., Gassner F., Merkenschlager M.   +2 more
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Reaction of Pteridine and Its 8-0xide with Grignard Reagents, Regioselective 7-Alkylation of Pteridine

Pteridines, 1995
Reaction of 2-amino-4-butoxypteridine (1) with alkyl- or phenylmagnesium bromide followed by protonative and oxidative work-up with a solution of iodine in acetic acid gives 7 -alkyl- or 7 -phenylpteridines (2 ).
Kiguchi Kenji, Murata Shizuaki, Sugimoto Takashi   +2 more
doaj   +1 more source

Synthesis of 7-Acyl-2,4-disubstituted Pteridines by Radical Nucleophilic Substitution and Displacement Reactions

Pteridines, 2004
2,4-Disubstituted pteridine derivatives (1-3) react with acyl radicals very selectively in position 7 by a nucleophilic Substitution mechanism (4-10).
Döring Thomas, Boruah Romesh C., Pfleiderer Wolfgang   +2 more
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(2-Amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)cobalt(II) trihydrate

Acta Crystallographica Section E, 2013
In the title compound, [Co(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate ligand, a bidentate ancillary 1,10-phenanthroline (phen) ligand and a water molecule complete a distorted octahedral geometry ...
Siddhartha S. Baisya, Samir Sen, Parag S. Roy   +2 more
doaj   +1 more source

Pteridines, XCVI. Synthesis and Reactions of 6-(1,2,3-Trihydroxypropyl)pteridines

Pteridines, 1990
Various hydropyrano [3.2-g] pteridines (7, 10, 12, 21 , 33) were oxidized to the corresponding 6-(1,2,3- trihydroxypropyl)pteridine derivatives (8,9, 11, 13,32, 34), which are valuable intermediates for the synthesis of new 6-substituted pteridines (15 -
Soyka Rainer, Pfleiderer Wolfgang
doaj   +1 more source

Transcriptome Analysis Reveals That Alfalfa Promotes Rumen Development Through Enhanced Metabolic Processes and Calcium Transduction in Hu Lambs

Frontiers in Genetics, 2019
A healthy gut is very important for young animal development. The rumen of ruminants expands in size with the colonization of microbiota by 2 months of age. This process is promoted by alfalfa intervention.
Bin Yang, Hongwei Chen, Jiawen Cao, Bo He, Shanshan Wang, Yang Luo, Jiakun Wang   +6 more
doaj   +1 more source

In vitro Mutagenesis of Human Dihydropteridine Reductase at the Active Site and at Altered Sites Found in the Reductases of Deficient Children

Pteridines, 1996
A general procedure for in vitro site-directed mutagenesis of the wild-type dihydropteridine reductase gene has been used successfully to make eight mutant proteins.
Zhang Hong-Ping, Yang Nan, Armarego Wilfred L. F.   +2 more
doaj   +1 more source