Results 31 to 40 of about 10,390 (256)

Adsorption and Vibrational Study of Folic Acid on Gold Nanopillar Structures Using Surface-enhanced Raman Scattering Spectroscopy [PDF]

open access: yes, 2015
This paper presents a study of adsorption and vibrational features of folic acid, using surface-enhanced Raman scattering (SERS). A gold-capped silicon nanopillar (Au NP) with a height of 600 nm and a width of 120 nm was utilized to study the vibrational
Boisen, Anja   +3 more
core   +3 more sources

Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity [PDF]

open access: yes, 2017
Flavonoids have previously been identified as antiparasitic agents and pteridine reductase 1 (PTR1) inhibitors. Herein, we focus our attention on the chroman-4-one scaffold.
Alcantara, Laura M   +19 more
core   +3 more sources

Pteridines in the Assessment of Neoplasia [PDF]

open access: yescclm, 1982
Biological processes which might explain the association of pteridine excretion with proliferation are still unknown. Difficulties in the analysis and the determination of naturally occurring pteridines are described. The best quantitative estimations were achieved when measurement of non-reduced forms was attempted.
HAUSEN, A., Wachter, H.
openaire   +2 more sources

Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin

open access: yesPteridines, 2002
In the vasculature, a physiologic production of nitric oxide (NO) is maintained by endothelial nitric oxide synthase (eNOS). Induction of inducible nitric oxide synthase (ÍNOS) under inflammatory conditions (e.g. septic shock) resulting in high levels of
Mueller Nicolas J   +4 more
doaj   +1 more source

Evaluation of Serum and Urinary Levels of some Pteridine Pathway Components in Healthy Turkish Children

open access: yesPteridines, 2012
Neopterin, as a non-conjugated pteridine, is synthesized from guanosine triphosphate and its production is upregulated upon the activation of cellular immune response.
Girgin Gözde   +5 more
doaj   +1 more source

Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]

open access: yes, 2011
Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin   +4 more
core   +1 more source

Exploring the scope of DBU-promoted amidations of 7-carboxymethyl-pterin [PDF]

open access: yes, 2020
Pteridines are an important heterocycle often used in the development of pharmaceutically relevant compounds, and in the field of supramolecular chemistry.
Bockman, Anna
core   +1 more source

Analysis by RNA-seq of transcriptomic changes elicited by heat shock in Leishmania major [PDF]

open access: yes, 2019
Besides their medical relevance, Leishmania is an adequate model for studying post-transcriptional mechanisms of gene expression. In this microorganism, mRNA degradation/stabilization mechanisms together with translational control and post-translational ...
Aguado, Begoña   +5 more
core   +2 more sources

1H-Benzo[g]pteridine-2,4-dione

open access: yesIUCrData, 2023
The structure of the title compound, C10H6N4O2, reported by Smalley et al. [(2021). Cryst. Growth Des. 22, 524–534] from powder diffraction data and 15N NMR spectroscopy, is confirmed using low-temperature data from a twinned crystal. The tautomer in the
Rao M. Uppu, Frank R. Fronczek
doaj   +1 more source

Sequence-Based Mapping and Genome Editing Reveal Mutations in Stickleback Hps5 Cause Oculocutaneous Albinism and the casper Phenotype. [PDF]

open access: yes, 2017
Here, we present and characterize the spontaneous X-linked recessive mutation casper, which causes oculocutaneous albinism in threespine sticklebacks (Gasterosteus aculeatus).
Hart, James C, Miller, Craig T
core   +2 more sources

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