Results 41 to 50 of about 10,444 (253)

Colour Morphs as Alternative Solutions to the Trade‐Off Predicted by the Immuno‐Competence Handicap Hypothesis

Integrative Zoology, EarlyView.
In this study, we tested whether white and yellow morphs of the common wall lizard (Podarcis muralis) adopt alternative strategies shaped by the immuno‐competence handicap hypotheses (ICHH). We found that testosterone‐induced immune suppression was stronger in white males, while aggression decreased in both morphs.
Roberto Sacchi, Alan J. Coladonato, Stefano Scali, Marco A. L. Zuffi, Rupert Palme, Marco Mangiacotti   +5 more
wiley   +1 more source

In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase

Molecules, 2023
The parasites Trypanosoma brucei (Tb) and Leishmania major (Lm) cause the tropical diseases sleeping sickness, nagana, and cutaneous leishmaniasis. Every year, millions of humans, as well as animals, living in tropical to subtropical climates fall victim
Katharina Possart, Fabian C. Herrmann, Joachim Jose, Thomas J. Schmidt   +3 more
doaj   +1 more source

Eye can see clearly now: Identifying the locus associated with a white‐eye mutation in honey bees (Apis mellifera)

Insect Molecular Biology, EarlyView.
We performed a community science investigation with the beekeepers nationwide to find phenotypic mutants. Alongside a beekeeper in Kentucky, we performed a GWAS to identify a region associated with a white‐eye phenotype. We identified an eight bp region in a non‐coding RNA strongly associated with white eyes.
Riley R. Shultz, Dylan K. Ryals, Phillip Patterson, Jonathan M. Nixon, Izaak R. Gilchrist, Brock A. Harpur   +5 more
wiley   +1 more source

The Physarum polycephalum genome reveals extensive use of prokaryotic two-component and metazoan-type tyrosine kinase signaling [PDF]

, 2015
Physarum polycephalum is a well-studied microbial eukaryote with unique experimental attributes relative to other experimental model organisms. It has a sophisticated life cycle with several distinct stages including amoebal, flagellated, and plasmodial
et al,, Fronick, Catrina, Fulton, Lucinda, Minx, Pat, Tomlinson, Chad, Warren, Wesley C, Wilson, Richard K   +6 more
core   +9 more sources

Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

Pteridines, 1997
The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied.
Horejsi Renate, Daczki Jürgen, Mölller Reinhard, Öttl Karl, Vrecko Karoline, Reibnegger Gilbert   +5 more
doaj   +1 more source

Alloxazine derivatives as multifunctional agents for photodynamic therapy, cancer cell imaging, and cell proliferation inhibition

Photochemistry and Photobiology, EarlyView.
Alloxazine photosensitizers, molecularly engineered through sugar conjugation and methoxy substitution to enhance solubility, photodynamic potency, and fluorescence, enable image‐guided photodynamic therapy while inhibiting cancer cell growth in the absence of photoactivation.
Rubej R. Khan, Sourav Kanti Seth, Reshma Mathew, Nitza V. Falcón‐Cruz, Chris Acquah, Steffen Jockusch, Liraz Levi, Carlos E. Crespo‐Hernández   +7 more
wiley   +1 more source

How consistent are the transcriptome changes associated with cold acclimation in two species of the Drosophila virilis group? [PDF]

, 2015
This work was financially support by a Marie Curie Initial Training Network grant, “Understanding the evolutionary origin of biological diversity” (ITN-2008–213780 SPECIATION), grants from the Academy of Finland to A.H.
A Hoikkala, A Laiho, A Martin, A Sasson, AA Hoffmann, AL Majumder, AR McCune, B Katz, BJ Sinclair, C Canestro, CJ Reaume, CP Downes, D Arbuthnott, D Bell-Pedersen, D J Parker, DW Huang, DW Huang, FA Loewus, H Colinet, H Colinet, HA MacMillan, J Overgaard, J Zhang, JR Hazel, K Xu, KB Storey, KY Xu, L Kivivuori, L Vesala, L Vesala, L Vesala, LH Throckmorton, M G Ritchie, M Kankare, M Kim, M Reis, M Watanabe, M Watanabe, MC Magnone, MD Robinson, MD Robinson, MJ Fitzpatrick, MK Jones, MV Rockman, NM Teets, PR Senthilan, PW Hochachka, R David, R Morales-Hojas, R Niwa, RE Lee, RE Lee, RM Robich, RW Salt, S Anders, S Fowler, S Sahar, S Tweedie, V Kellermann, V Kostal, V Koštál, V Koštál, Vr Koštál, W Block, W Huang, WJ Heitler, WL Shen, X Huang, XL Guan, Y Benjamini, ZD Liu   +70 more
core   +2 more sources

Localization of Sepiapterin Deaminase and Pteridines In the Granules In Epidermal Cells of the Silkworm, Bombyx mori

Pteridines, 1990
A new method for assay of sepiapterin deaminase (3.5.4.24) activity by use of high performance liquid chromatography (HPLC) was developed. By this sensitive method the enzyme activity in the cell organelle was assayed.
Tsusué M., Kuroda S., Sawada H.
doaj   +1 more source

Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster

eLife, 2017
Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors.
Hyun Bong Park, Corey E Perez, Karl W Barber, Jesse Rinehart, Jason M Crawford   +4 more
doaj   +1 more source

Thyroid hormone regulates distinct paths to maturation in pigment cell lineages [PDF]

, 2019
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion, yet
Aman, Andrew J, Corbo, Joseph C, Lewis, Victor M, McFaline-Figueroa, Jose L, Mishra, Abhishek K, Packer, Jonathan S, Parichy, David M, Qiu, Xiaojie, Saunders, Lauren M, Toomey, Matthew B, Trapnell, Cole   +10 more
core   +1 more source