Results 51 to 60 of about 10,390 (256)

Pteridine-2,4-diamine derivatives as radical scavengers and inhibitors of lipoxygenase that can possess anti-inflammatory properties [PDF]

open access: yes, 2015
BACKGROUND: Reactive oxygen species are associated with inflammation implicated in cancer, atherosclerosis and autoimmune diseases. The complex nature of inflammation and of oxidative stress suggests that dual-target agents may be effective in combating ...
Hadjipavlou-Litina, D   +4 more
core   +1 more source

Colour Morphs as Alternative Solutions to the Trade‐Off Predicted by the Immuno‐Competence Handicap Hypothesis

open access: yesIntegrative Zoology, EarlyView.
In this study, we tested whether white and yellow morphs of the common wall lizard (Podarcis muralis) adopt alternative strategies shaped by the immuno‐competence handicap hypotheses (ICHH). We found that testosterone‐induced immune suppression was stronger in white males, while aggression decreased in both morphs.
Roberto Sacchi   +5 more
wiley   +1 more source

In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase

open access: yesMolecules, 2023
The parasites Trypanosoma brucei (Tb) and Leishmania major (Lm) cause the tropical diseases sleeping sickness, nagana, and cutaneous leishmaniasis. Every year, millions of humans, as well as animals, living in tropical to subtropical climates fall victim
Katharina Possart   +3 more
doaj   +1 more source

Eye can see clearly now: Identifying the locus associated with a white‐eye mutation in honey bees (Apis mellifera)

open access: yesInsect Molecular Biology, EarlyView.
We performed a community science investigation with the beekeepers nationwide to find phenotypic mutants. Alongside a beekeeper in Kentucky, we performed a GWAS to identify a region associated with a white‐eye phenotype. We identified an eight bp region in a non‐coding RNA strongly associated with white eyes.
Riley R. Shultz   +5 more
wiley   +1 more source

Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

open access: yesPteridines, 1997
The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied.
Horejsi Renate   +5 more
doaj   +1 more source

Photo-reduction of Pteridines [PDF]

open access: yesNature, 1956
WHEN a solution of 7-hydroxypteridine1 was spotted on a sheet of Whatman No. 1 filter paper, irradiated with ultra-violet light (principally 254 mµ) for 5 min., and developed (by ascending chromatography) in various solvents, two spots appeared. One of these was identical with the starting material (unirradiated material was used as a control on the ...
openaire   +2 more sources

Individual identification of bony fishes using unique body markings: Implications and applications

open access: yesJournal of Fish Biology, EarlyView.
Abstract The natural variation in animal body markings, such as spots, stripes and blotches, offers a powerful tool for researchers, conservationists, citizen scientists and resource managers to distinguish specific individuals within species. By building libraries of photo‐identified individuals, we can track and differentiate individuals over time ...
Katie Dunkley   +6 more
wiley   +1 more source

Thyroid hormone regulates distinct paths to maturation in pigment cell lineages [PDF]

open access: yes, 2019
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion, yet
Aman, Andrew J   +10 more
core   +1 more source

Alloxazine derivatives as multifunctional agents for photodynamic therapy, cancer cell imaging, and cell proliferation inhibition

open access: yesPhotochemistry and Photobiology, EarlyView.
Alloxazine photosensitizers, molecularly engineered through sugar conjugation and methoxy substitution to enhance solubility, photodynamic potency, and fluorescence, enable image‐guided photodynamic therapy while inhibiting cancer cell growth in the absence of photoactivation.
Rubej R. Khan   +7 more
wiley   +1 more source

Localization of Sepiapterin Deaminase and Pteridines In the Granules In Epidermal Cells of the Silkworm, Bombyx mori

open access: yesPteridines, 1990
A new method for assay of sepiapterin deaminase (3.5.4.24) activity by use of high performance liquid chromatography (HPLC) was developed. By this sensitive method the enzyme activity in the cell organelle was assayed.
Tsusué M., Kuroda S., Sawada H.
doaj   +1 more source

Home - About - Disclaimer - Privacy