Results 61 to 70 of about 13,736 (293)
We demonstrate the efficient use of CRISPR/Cas9 to generate germline loss‐of‐function (LOF) mutations in the speckled wood butterfly (Pararge aegeria), an ecological model species. Targeting the yellow‐y gene, we achieved nearly 80% mosaic LOF phenotypes in adults and high germline mutation rates in offspring.
Anna B. Shoshan+3 more
wiley +1 more source
In a continuation of our computational efforts to find new natural inhibitors of a variety of target enzymes from parasites causing neglected tropical diseases (NTDs), we now report on 15 natural products (NPs) that we have identified as inhibitors of ...
F. Herrmann+5 more
semanticscholar +1 more source
The increase in urban lands and the vegetation loss implies changes in the colour of the background which in turn could cause changes in the coloration of individuals. We measured changes in body lightness of damselflies through 19 sites in Central Mexico, with a different degree of urbanisation and a different percentage of native vegetation. We found
Teresa L. Ramos‐Merino+1 more
wiley +1 more source
A new method for assay of sepiapterin deaminase (3.5.4.24) activity by use of high performance liquid chromatography (HPLC) was developed. By this sensitive method the enzyme activity in the cell organelle was assayed.
Tsusué M., Kuroda S., Sawada H.
doaj +1 more source
Photo-reduction of Pteridines [PDF]
WHEN a solution of 7-hydroxypteridine1 was spotted on a sheet of Whatman No. 1 filter paper, irradiated with ultra-violet light (principally 254 mµ) for 5 min., and developed (by ascending chromatography) in various solvents, two spots appeared. One of these was identical with the starting material (unirradiated material was used as a control on the ...
openaire +3 more sources
Prediction of Fragmentation Pathway of Natural Products, Antibiotics, and Pesticides by ChemFrag
ABSTRACT Because the manual interpretation of ESI‐MSn fragmentation spectra is time‐consuming and usually requires expert knowledge, automated annotation is often sought. The fragmentation software ChemFrag enables the annotation of MSn spectra by combining a rule‐based fragmentation and a semiempirical quantum chemical approach.
Jördis‐Ann Schüler+4 more
wiley +1 more source
Occurrence and significance of folic acid
Folic acid is a naturally occurring pteridine, which was originally isolated from plants. Folic acid (pteroyl-glutamic acid) is composed of pteridine (6-methylptero), p-aminobenzoic acid (PABA) and glutamic acid.
Cieślik Ewa, Cieślik Iwona
doaj +1 more source
Development and validation of chromatographic methods to study folate derivatives produced by yeasts [PDF]
Folate, or folic acid, is an important water soluble B vitamin that exists in many different forms. Its presence is necessary for synthesis of DNA and RNA and methylation of homocysteine to methionine.
Patring, Johan
core
ABSTRACT Ectothermic vertebrates exhibit a diverse array of pigment cell types—chromatophores—that provide valuable opportunities to uncover mechanisms of fate specification and how they evolve. Like melanocytes of mammals, the melanophores of teleosts and other ectotherms depend on basic helix–loop–helix leucine zipper transcription factors encoded by
Katia G. Korzeniwsky+5 more
wiley +1 more source
Urinary pteridines as a discriminator of atherosclerotic risk in patients with diabetes
Background and aims: We have recently proposed urinary pteridine level as a useful biomarker of oxidative stress in a general population. However, the significance of urinary pteridines in patients with diabetes is unknown.
Mikio Marumo+2 more
doaj