Results 71 to 80 of about 10,444 (253)
First Synthesis of a Natural Isoxanthopterin Glycoside, Asperopterin-A [PDF]
The key precursor, N-2-(N,N-dimethylaminomethylene)-6-hydroxymethy1-8-methyl-3[2-(4-nitrophenypethyl]-7-xanthopterin (9) was efficiently prepared from 2,5-diamino-6-methylam1no-3H-pyrimidin-4-one (3) and ethyl 3-(tert-butyldimethylsilyloxy)-2 ...
Ejiri, Kazumasa +2 more
core +1 more source
The colour of amphibian skin and eyes is the result of light interacting with multiple chromatophores (xanthophores, iridophores and melanophores), leading to challenges when trying to identify which of these cells are involved in colour abnormalities.
John Gould
wiley +1 more source
Electrochemical Hydrogenation of N‐Heterocycles and Related Substrates: A Mini‐Review
ABSTRACT Catalytic hydrogenation refers to the (often) metal‐mediated addition of dihydrogen (H2) equivalents to unsaturated compounds to form new element‐hydrogen bonds. This conceptually simple reaction is ubiquitous in the production of a vast number of essential chemicals.
Esteban Garcia‐Torres +1 more
wiley +1 more source
Abstract Colour signals play pivotal roles in different communication systems, and the evolution of these characters has been associated with behavioural ecology, integumentary production processes and perceptual mechanisms of the species involved. Here, we present the first insight into the molecular and histological basis of skin colour polymorphism ...
Juliane P. C. Monteiro +7 more
wiley +1 more source
Early Diagnosis of 6-Pyruvoyl-tetrahydropterin Synthase Deficiency
6-Pyruvoyl-tetrahydropterin synthase (PTPS) deficiency, which used to be called dihydrobiopterin synthase deficiency, is the most common kind of tetrahydrobiopterin deficiency. Early treatment by administration of tetrahydrobiopterin and neurotransmitter
Shintaku Haruo
doaj +1 more source
Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin [PDF]
In the vasculature, a physiologic production of nitric oxide (NO) is maintained by endothelial nitric oxide synthase (eNOS). Induction of inducible nitric oxide synthase (ÍNOS) under inflammatory conditions (e.g. septic shock) resulting in high levels of
Linscheid, Philippe +4 more
core
SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor Growth in Vivo by inducing G2/M cell cycle arrest [PDF]
Protein kinase D (PKD) has been implicated in many aspects of tumorigenesis and progression, and is an emerging molecular target for the development of anticancer therapy.
Carder, EJ +8 more
core +3 more sources
We demonstrate the efficient use of CRISPR/Cas9 to generate germline loss‐of‐function (LOF) mutations in the speckled wood butterfly (Pararge aegeria), an ecological model species. Targeting the yellow‐y gene, we achieved nearly 80% mosaic LOF phenotypes in adults and high germline mutation rates in offspring.
Anna B. Shoshan +3 more
wiley +1 more source
Reaction of 2-amino-4-butoxypteridine (1) with alkyl- or phenylmagnesium bromide followed by protonative and oxidative work-up with a solution of iodine in acetic acid gives 7 -alkyl- or 7 -phenylpteridines (2 ).
Kiguchi Kenji +2 more
doaj +1 more source
Numerical taxonomy of moderately halophilic Gram-negative rods [PDF]
A study was made of 516 randomly selected isolates of moderately halophilic bacteria from solar salterns showing salinities between 8.8 and 40.0% (w/v) total salts, located in S.E. Spain.
Quesada Arroquia, Emilia +4 more
core +1 more source

