Results 71 to 80 of about 10,390 (256)

The Role of Neopterin and Interleukin‐6 Detection in Saliva and Plasma in Oral and Oropharyngeal Cancer Patients: A Prospective Study

Clinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.
ABSTRACT Objectives The incidence of oral and oropharyngeal cancer is continually rising and affects increasingly younger patients. Consequently, many studies focus on early diagnosis using appropriate biomarkers. Neopterin and interleukin‐6 (IL‐6) are promising predictive and prognostic markers of immune response activation, both systemic and local ...
Lenka Šašková, Peter Tvrdý, Bohuslav Melichar, Josef Tomandl, Jana Zapletalová, Michal Mozol'a, Petr Michl, David Král, Richard Pink   +8 more
wiley   +1 more source

Genomic Characterisation of Limosilactobacillus fermentum CRL2085 Unveiling Probiotic Traits for Application in Cattle Feed

Environmental Microbiology Reports, Volume 17, Issue 5, October 2025.
A comprehensive genomic and phenotypic analysis of Limosilactobacillus fermentum CRL2085 revealed key probiotic and nutritional traits supporting its safe application in cattle feed. The strain harbors genes for stress tolerance, adhesion, exopolysaccharide production, and B‐vitamin biosynthesis, and efficiently metabolizes plant‐derived carbohydrates,
Cecilia M. Aristimuño Ficoseco, Daniele Chieffi, Marco Montemurro, Annarita Bavaro, Carlo G. Rizzello, Maria E. F. Nader‐Macias, Silvina Fadda, Francesca Fanelli, Vincenzina Fusco, Graciela M. Vignolo   +9 more
wiley   +1 more source

Colour Confusion: Reviewing Ambiguities in the Identification and Classification of Chromatophore Deficiencies Among Amphibians

Ecology and Evolution, Volume 15, Issue 9, September 2025.
The colour of amphibian skin and eyes is the result of light interacting with multiple chromatophores (xanthophores, iridophores and melanophores), leading to challenges when trying to identify which of these cells are involved in colour abnormalities.
John Gould
wiley   +1 more source

Electrochemical Hydrogenation of N‐Heterocycles and Related Substrates: A Mini‐Review

Electrochemical Science Advances, Volume 5, Issue 4, August 2025.
ABSTRACT Catalytic hydrogenation refers to the (often) metal‐mediated addition of dihydrogen (H2) equivalents to unsaturated compounds to form new element‐hydrogen bonds. This conceptually simple reaction is ubiquitous in the production of a vast number of essential chemicals.
Esteban Garcia‐Torres, David E. Herbert   +1 more
wiley   +1 more source

Expression patterns of melanin‐related genes are linked to crypsis and conspicuousness in a pumpkin toadlet

Molecular Ecology, Volume 34, Issue 15, August 2025.
Abstract Colour signals play pivotal roles in different communication systems, and the evolution of these characters has been associated with behavioural ecology, integumentary production processes and perceptual mechanisms of the species involved. Here, we present the first insight into the molecular and histological basis of skin colour polymorphism ...
Juliane P. C. Monteiro, Heike Pröhl, Mariana L. Lyra, Andrés E. Brunetti, Eli C. de Nardin, Thais H. Condez, Célio F. B. Haddad, Ariel Rodríguez   +7 more
wiley   +1 more source

Early Diagnosis of 6-Pyruvoyl-tetrahydropterin Synthase Deficiency

Pteridines, 1994
6-Pyruvoyl-tetrahydropterin synthase (PTPS) deficiency, which used to be called dihydrobiopterin synthase deficiency, is the most common kind of tetrahydrobiopterin deficiency. Early treatment by administration of tetrahydrobiopterin and neurotransmitter
Shintaku Haruo
doaj   +1 more source

Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin [PDF]

, 2017
In the vasculature, a physiologic production of nitric oxide (NO) is maintained by endothelial nitric oxide synthase (eNOS). Induction of inducible nitric oxide synthase (ÍNOS) under inflammatory conditions (e.g. septic shock) resulting in high levels of
Linscheid, Philippe, Mueller, Nicolas J., Schaffner, Andreas, Schoedon, Gabriele, Walter, Roland Β.   +4 more
core  

A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]

, 2010
Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M, Hermann, Thomas, Parsons, Jerod   +2 more
core   +3 more sources

Highly Efficient Generation of Germline Mutations Using CRISPR/Cas9 in the Speckled Wood Butterfly Pararge aegeria

Ecology and Evolution, Volume 15, Issue 7, July 2025.
We demonstrate the efficient use of CRISPR/Cas9 to generate germline loss‐of‐function (LOF) mutations in the speckled wood butterfly (Pararge aegeria), an ecological model species. Targeting the yellow‐y gene, we achieved nearly 80% mosaic LOF phenotypes in adults and high germline mutation rates in offspring.
Anna B. Shoshan, Kalle Tunström, Christopher W. Wheat, Karl Gotthard   +3 more
wiley   +1 more source

Pteridines, IXC. Synthesis, Oxidations and Reactions of 6- and 7-Hydroxy-2-thiolumazines Selective Cytotoxicity of Carboxypeptidase-activated Methotrexate ex-Peptides

Pteridines, 1989
Various 6-(10, 11) and 7-hydroxy-2-thiolumazines (8,9) have been synthesized and oxidations of the thioamide function studied . H20 2 Oxidation of 7-hydroxy-2-thiolumazine (8) in basic medium leads to pteridine-4,7- dione-2-sulfinate (12), which ...
Bartke Michael, Pfleiderer Wolfgang
doaj   +1 more source