Results 71 to 80 of about 13,736 (293)

Urinary Oxidative Damage Markers and Their Association with Obesity-Related Metabolic Risk Factors

Antioxidants, 2022
Oxidative damage and inflammation are possible mechanisms linking obesity to diabetes and related complications. This study investigates the levels of oxidative damage markers in the urine of community free-living subjects with increased prevalence of ...
Salah Gariballa, Abderrahim Nemmar, Ozaz Elzaki, Nur Elena Zaaba, Javed Yasin   +4 more
doaj   +1 more source

Thyroid hormone regulates distinct paths to maturation in pigment cell lineages [PDF]

, 2019
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion, yet
Aman, Andrew J, Corbo, Joseph C, Lewis, Victor M, McFaline-Figueroa, Jose L, Mishra, Abhishek K, Packer, Jonathan S, Parichy, David M, Qiu, Xiaojie, Saunders, Lauren M, Toomey, Matthew B, Trapnell, Cole   +10 more
core   +1 more source

1,3,7-Trimethyl-2,4-dioxo-1,2,3,4-tetrahydropteridine-6-carboxylic acid hemihydrate

Acta Crystallographica Section E, 2010
In the title compound, C10H10N4O4·0.5H2O, the two rings of the pteridine system are nearly coplanar [dihedral angle = 4.25 (9)°]. The atoms of the carboxyl group are also coplanar with the pteridine unit [r.m.s. deviation from
Miguel N. Moreno-Carretero, Fátima M. Linares-Ordóñez, Sonia B. Jiménez-Pulido, René Faure, Nuria A. Illán-Cabeza   +4 more
doaj   +1 more source

Trypanosoma brucei DHRF-TS revisited:characterisation of a bifunctional and highly unstable recombinant dihydrofolate reductase-thymidylate synthase [PDF]

, 2016
Bifunctional dihydrofolate reductase–thymidylate synthase (DHFR-TS) is a chemically and genetically validated target in African trypanosomes, causative agents of sleeping sickness in humans and nagana in cattle.
A Dawson, A El Fadili, A Khodursky, AJ Wahba, AJ Wahba, AL Jackman, Alan H. Fairlamb, B Nare, BJ Dolnick, C Fraser-Lhostis, C Shih, CJ Allegra, CW Carreras, D Spinks, DC Jones, E Wirtz, EJ Shanks, EL White, F Gamarro, FW Studier, H Zhang, Han B. Ong, HB Ong, J Phan, J Yuvaniyama, JA Frearson, Jayne Raper, JF Morrison, JM Blaney, JR Appleman, K Al Chalabi, KY Han, LM Changchien, LS Torrie, M Berriman, M Hekmat-Nejad, Marc W. Gibson, MM Bradford, N Greig, N Sienkiewicz, N Sienkiewicz, Natasha Sienkiewicz, ND Brunn, P Prapunwattana, P Reche, PH Liang, R Ferone, R Grumont, RA Copeland, RC Jackson, RD Walter, RJ Bonney, RJ Cisneros, S Shallom, SA Margosiak, SE Webber, SF Chowdhury, SI Ahmad, Simon Dewar, SM Lanham, TC Eadsforth, TD Meek, TW Synold, Y Cheng   +63 more
core   +3 more sources

Being red, blue and green: the genetic basis of coloration differences in the strawberry poison frog (Oophaga pumilio)

BMC Genomics, 2020
Background Animal coloration is usually an adaptive attribute, under strong local selection pressures and often diversified among species or populations.
Ariel Rodríguez, Nicholas I. Mundy, Roberto Ibáñez, Heike Pröhl   +3 more
doaj   +1 more source

Chemical structure of 1-O-(L-erythro-biopterin-2'-yl)-a-glucose isolated from a cyanobacterium Synechococcus sp. PCC 7942

Pteridines, 2001
A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee, Hwang Yoon Kyung, Kang Yong Han, Park Young Shik   +3 more
doaj   +1 more source

Dilute-and-Shoot-Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry for Pteridine Profiling in Human Urine and Its Association with Different Pathologies

Chemosensors, 2023
Pteridines are a group of compounds synthesised by many living organisms that are involved in the metabolism of many cofactors and vitamins. Their concentration in biological fluids may be altered by various pathologies such as cancer or inflammatory ...
Claudia Giménez-Campillo, Marta Pastor-Belda, Natalia Arroyo-Manzanares, Natalia Campillo, Blanca del Val Oliver, José Zarauz-García, Luis Sáenz, Pilar Viñas   +7 more
doaj   +1 more source

Molecular Design Leveraging Non‐Covalent Interactions for Efficient Light‐Emitting Organic Small Molecules

Advanced Functional Materials, Volume 35, Issue 2, January 9, 2025.
This review elucidates the design of leveraging non‐covalent interactions (NCIs) effect on light‐emitting organic small molecules to achieve highly efficient emission characteristics. Representative organic emitters ranging from ultraviolet to near‐infrared regions are listed and investigated.
Taehyun Kim, Giwon Shin, Taiho Park, Minjun Kim   +3 more
wiley   +1 more source

The role of urinary pteridines as disease biomarkers

Pteridines, 2017
Pteridines and their derivatives function as intermediates in the metabolism of several vitamins and cofactors, and their relevance to disease has inspired new efforts to study their roles as disease biomarkers.
Burton Casey, Ma Yinfa
doaj   +1 more source

Antitumor studies. Part 1: Design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents [PDF]

, 2006
Novel 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides were prepared as a new class of antitumor agents and showed significant antitumor activities against NCI-H 460, HCT 116, A 431, CCRF-HSB-2, and KB cell lines. In vivo investigation,
Akaho, Eiichi, Ali, Hamed I.., Ashida, Noriyuki, Hayakawa, Hiroyuki, Ikeya, Hisao, Kambara, Hiroto, Kawashima, Yutaka, Miura, Shinji, Nagamatsu, Tomohisa, Tomita, Keiichiro, Yamagishi, Takehiro, Yoneda, Fumio   +11 more
core   +1 more source