Results 51 to 60 of about 5,912 (161)

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Fluorescence of pterin, 6-formylpterin, 6-carboxypterin and folic acid in aqueous solution: pH effects [PDF]

, 2022
Steady-state and time-resolved studies have been performed on four compounds of the pterin family (pterin, 6-carboxypterin, 6-formylpterin and folic acid) in aqueous solution, using the single photon counting technique.
Lorente, Carolina, Thomas, Andrés Héctor, Capparelli, Alberto Luis, Oliveros, Esther, Pokhrel, Megh Raj, Braun, André M.   +5 more
core  

Quantification of Live Bacterial Sensing for Chemotaxis and Phagocytosis and of Macropinocytosis

Frontiers in Cellular and Infection Microbiology, 2018
Initial immunological defense mechanisms to pathogen invasion rely on innate pathways of chemotaxis and phagocytosis, original to ancient phagocytes. Although chemotaxis has been well-studied in mammalian and model systems using purified chemoattractants
Netra P. Meena, Alan R. Kimmel
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Synthesis, Anti‐Leishmania amazonensis Activity, Cytotoxicity, and Molecular Docking of Anthranilate–Naphthoquinone Hybrids

ChemistrySelect, Volume 11, Issue 40, 27 October 2026.
New anthranilate–naphthoquinone hybrids display potent inhibition of Leishmania (L.) amazonensis with low host cell toxicity. Molecular docking reveals key interactions with TR, GP63, and PTR1, suggesting a multitarget mechanism that contributes to parasite death.
Eduardo Miranda da Silva Magesfeste, Lidilhone Hamerski, Diego Mendes Nunes, Ana Paula Sotero da Silva Ribeiro, Elvira Maria Saraiva, Magaly Girão Albuquerque, Camilo Henrique da Silva Lima, Bárbara Vasconcellos da Silva   +7 more
wiley   +1 more source

Fluorescence of pterin, 6-formylpterin, 6-carboxypterin and folic acid in aqueous solution: pH effects [PDF]

, 2002
Steady-state and time-resolved studies have been performed on four compounds of the pterin family (pterin, 6-carboxypterin, 6-formylpterin and folic acid) in aqueous solution, using the single photon counting technique.
Lorente, Carolina, Thomas, Andrés Héctor, Capparelli, Alberto Luis, Oliveros, Esther, Pokhrel, Megh Raj, Braun, André M., Alberto L. Capparelli, André M. Braun, Esther Oliveros, Carolina Lorente, Andrés H. Thomas, Megh Raj Pokhrel   +11 more
core   +1 more source

Identification of a pterin as the acrasin of the cellular slime mold Dictyostelium lacteum [PDF]

, 1982
Cell aggregation in Dictyostelium discoideum is mediated by chemotaxis to cyclic AMP. Aggregative cells of the simpler species D. lacteum are not attracted by this cyclic nucleotide. We describe how the cell aggregation-inducing factor, or acrasin, of D.
Grijpma, Yvonne, Haastert, Peter J.M. van, Konijn, Theo M., Wit, René J.W. de   +3 more
core   +1 more source

Advances in Cold‐Plasma Technology for Legume Seeds: Mechanisms, Nutritional Quality Improvement, Food Safety and Sustainable Agriculture

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Cold plasma (CP), a nonthermal ionised gas rich in reactive oxygen and nitrogen species (RONS), has emerged as a sustainable technology for enhancing legume production and quality. This review summarises current advances in CP applications in legumes, focusing on seed germination, seedling vigour, nutrient enhancement, antinutrient reduction ...
Jannatul Ferdous, Joyairia Tabassum, Md. Hassan Bin Nabi, Abid Hassan Arnab, Wahidu Zzaman, Iftekhar Ahmad   +5 more
wiley   +1 more source

pH-Related and Site-Specific Excited-State Proton Transfer from Pterin to Acetate

, 2016
The pH-related fluorescence quenching mechanism of 2-amino-4-hydroxypteridine (pterin), a biologic functional molecule, in the presence of acetate ion has been fully investigated for the first time. Using a combined experimental and theoretical approach,
Dapeng Yang (484094), Peng Li (69518), Lei Liu (5074)   +2 more
core   +1 more source

Experimental and metabolic modeling evidence for a folate-cleaving side-activity of ketopantoate hydroxymethyltransferase (PanB)

Frontiers in Microbiology, 2016
Tetrahydrofolate (THF) and its one-carbon derivatives, collectively termed folates, are essential cofact¬ors, but are inherently unstable. While it is clear that chemical oxidation can cleave folates or damage their pterin precursors, very little is ...
Jennifer eThiaville, Océane eFrelin, Carolina eGarcía-Salinas, Ghulam eHasnain, Katherine eHarrison, Rocio eDíaz de la Garza, Nicole eHorenstein, Christopher eHenry, Andrew D Hanson, Valérie ede Crécy-Lagard   +9 more
doaj   +1 more source