Results 41 to 50 of about 5,912 (161)

The Indivisible System: Modeling The Metal-Pterin-Dithiolene System In Molybdenum And Tungsten Cofactors [PDF]

open access: yes, 2023
Mo and W enzymes are ubiquitous in living organisms and crucial for sustaining life. Mo and W enzyme variety is diverse, but they contain a highly conserved aspect of functionality in these enzymes, the pyranopterin-dithiolene (PDT) ligand.
Gates, Cassandra
core  

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

open access: yesSmall, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom   +6 more
wiley   +1 more source

Antagonists of chemoattractants reveal separate receptors for cAMP, folic acid and pterin in Dictyostelium [PDF]

open access: yes, 1982
Adenosine 3’,5’-monophosphate (cAMP), folic acid and pterin are chemoattractants in the cellular slime molds. The cAMP analog, 3’-amino-cAMP, inhibits a chemotactic reaction to cAMP at a concentration at which the analog is chemotactically inactive.
Haastert, Peter J.M. van   +2 more
core   +1 more source

Theoretical determination of two-photon absorption in biologically relevant pterin derivatives [PDF]

open access: yes, 2020
Given the prevalence of fluorescence spectroscopy in biological systems, and the prevalence of pterin derivatives throughout biological systems, presented here is an assessment of the two-photon absorption spectroscopy as it applies to a range of the ...
Malcomson, Thomas, Paterson, Martin J.
core   +3 more sources

Implications of Pyran Cyclization and Pterin Conformation on Oxidized Forms of the Molybdenum Cofactor [PDF]

open access: yes, 2018
The large family of mononuclear molybdenum and tungsten enzymes all possess the special ligand molybdopterin (MPT), which consists of a metal-binding dithiolene chelate covalently bound to a pyranopterin group.
Esmail, Alisha   +6 more
core   +2 more sources

One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives

open access: yesChemBioChem, Volume 27, Issue 19, 14 October 2026.
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler   +2 more
wiley   +1 more source

Photoinduced cleavage of plasmid DNA in the presence of pterin

open access: yesPteridines, 2000
The photoinduced cleavage of plasmid DNA by UV -A light in the presence of pterin was investigated. Electrophoretic analysis of the irradiated plasmid pUCI8 in the presence of pterin showed that UV light of 350 nm induced the transformation of a ...
Lorente Carolina   +5 more
doaj   +1 more source

Crystal structure of (2-amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(1,10-phenanthroline-κ2N,N′)copper(II) trihydrate

open access: yesActa Crystallographica Section E, 2014
In the title compound, [Cu(C8H5N5O3)(C12H8N2)(H2O)]·3H2O, the CuII cation is O,N,O′-chelated by the 2-amino-7-methyl-4-oxidopteridine-6-carboxylate anion and N,N′-chelated by the 1,10-phenanthroline (phen) ligand.
Siddhartha S. Baisya, Parag S. Roy
doaj   +1 more source

Molecular parallelisms between pigmentation in the avian iris and the integument of ectothermic vertebrates.

open access: yesPLoS Genetics, 2021
Birds exhibit striking variation in eye color that arises from interactions between specialized pigment cells named chromatophores. The types of chromatophores present in the avian iris are lacking from the integument of birds or mammals, but are ...
Pedro Andrade   +8 more
doaj   +1 more source

Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
Ricin toxin A chain (RTA), from Ricinus communis, is a deadly protein that inactivates ribosomes by degrading an adenine residue at position 4324 in 28S rRNA. Recently, we have demonstrated that pterin-7-carboxamides with peptide pendants were potent RTA
Masaru Goto   +5 more
doaj   +1 more source

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