Results 21 to 30 of about 4,377 (174)

Pterins in Human Urine

open access: yesJournal of Biological Chemistry, 1972
Abstract Qualitative and quantitative analyses for pterins (derivatives of 2-amino-4-hydroxypteridine) in human urine were carried out by an improved procedure which involved the use of two new weak ion exchangers, ECTEOLA-Sephadex and phospho-Sephadex.
T, Fukushima, T, Shiota
openaire   +2 more sources

A Bacterial Pterin Deaminase

open access: yesJournal of Biological Chemistry, 1959
Publisher Summary This chapter describes the bacterial pterin deaminase. In the standard assay, the mixture contains 0.05 ml of pterin carboxylic acid, 0.8 ml of phosphate buffer, and 0.02 to 0.15 ml of enzyme in a final volume of 1.0 ml. Incubation is carried out at 23° in a 1-ml Beckman quartz cuvette with a light path of 1.00 cm. Reaction is begun
B, LEVENBERG, O, HAYAISHI
openaire   +2 more sources

Direct coordination of pterin to Fe II enables neurotransmitter biosynthesis in the pterin-dependent hydroxylases [PDF]

open access: yesProceedings of the National Academy of Sciences, 2021
Significance The mononuclear pterin-dependent nonheme iron enzymes catalyze the rate-limiting step in neurotransmitter biosynthesis and are essential in maintaining proper brain function. These enzymes utilize molecular oxygen, a redox active pterin cofactor, and a ferrous active site to generate an Fe
Shyam R. Iyer   +13 more
openaire   +2 more sources

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen   +3 more
wiley   +2 more sources

(2-Amino-7-methyl-4-oxidopteridine-6-carboxylato-κ3O4,N5,O6)aqua(ethane-1,2-diamine-κ2N,N′)nickel(II) dihydrate

open access: yesActa Crystallographica Section E, 2013
The NiII atom in the title complex, [Ni(C8H5N5O3)(C2H8N2)(H2O)]·2H2O, is six-coordinated in a distorted octahedral geometry by a tridentate 2-amino-7-methyl-4-oxidopteridine-6-carboxylate (pterin) ligand, a bidentate ancillary ethane-1,2-diamine (en)
Siddhartha S. Baisya, Parag S. Roy
doaj   +1 more source

A concise treatment of pterins: some recent synthetic and methodology aspects and their applications in molecular sensors

open access: yesPteridines, 2018
A concise account of pterins in chemistry and biology and their applications in molecular sensors including their optical spectroscopic properties are described.
Goswami Shyamaprosad   +3 more
doaj   +1 more source

Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System

open access: yesPteridines, 1997
The effects of 17 different pteridine derivatives on rat liver microsomal cytochrome P-450 catalyzed degradation of aminoantipyrin were studied.
Horejsi Renate   +5 more
doaj   +1 more source

Molecular architecture of pterin deaminase from Saccharomyces cerevisiae NCIM 3458

open access: yesPteridines, 2017
As early as 1974, reports have confirmed the anticancer activity of pterin deaminase isolated from fungi. The enzyme has also been reported in bacteria, fungi and slime mold genera, but the enzyme characterization was effetely done.
Murugesan Thandeeswaran   +7 more
doaj   +1 more source

Tryptophan oxidation photosensitized by pterin

open access: yesFree Radical Biology and Medicine, 2013
Pterins are normal components of cells and they have been previously identified as good photosensitizers under UV-A irradiation, inducing DNA damage and oxidation of nucleotides. In this work, we have investigated the ability of pterin (Ptr), the parent compound of oxidized pterins, to photosensitize the oxidation of another class of biomolecules ...
Thomas, Andrés Héctor   +6 more
openaire   +3 more sources

Immunopterin: A prospective therapy and preventative to fight COVID-19?

open access: yesPteridines, 2022
The authors explore the therapeutic and prophylactic efficacies of Immunopterin (calcium pterin-6-carboxylate chelate) against coronavirus colds and as a therapy against COVID-19.
Moheno Phillip B. B., Fuchs Dietmar
doaj   +1 more source

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