Results 31 to 40 of about 4,377 (174)
The Journal of Infectious Diseases, 2021 Abstract Background Cerebral malaria (CM) pathogenesis remains incompletely understood. Having shown low systemic levels of tetrahydrobiopterin (BH4), an enzymatic cofactor for neurotransmitter synthesis, we hypothesized that BH4 and BH4-dependent neurotransmitters would likewise be low in ...
Matthew P Rubach +13 more
openaire +5 more sources
Plasma Levels of Neopterin and Biopterin in the Umbilical Vessels and the Maternal Vein
Pteridines, 2003 Tetrahydrobiopterin (BH4) is a highly bioactive pterin required for nitric oxide synthase and monooxygenases of aromatic amino acids, and is involved in the synthesis of nitric oxide, catecholamines and Serotonin.
Iwanaga Naoko +8 more
doaj +1 more source
Scientific Reports, 2023 The anaerobic region of the gastrointestinal (GI) tract has been replicated in the anaerobic chamber of a microbial fuel cell (MFC). Electroactive biomolecules released by the facultative anaerobes (Providencia rettgeri) under anoxic conditions have been
Sharda Nara +3 more
doaj +1 more source
Mechanistic Study of ROS-photogeneration by Pterin
Pteridines, 2011 Pterins are widespread in biological systems and possess photosensitizing activities. In the present study, the photosensitization mechanism of acid form of pterin (PTA) and basic form of pterin (PTB) is investigated by means of density functional theory
Ji Hong-Fang, Shen Liang
doaj +1 more source
2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Small, EarlyView.Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
wiley +1 more source
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen +3 more
wiley +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Eight chalcone‐sulfonamide hybrids (12a–h) are synthesized via Claisen–Schmidt condensation and evaluated for antibacterial, antioxidant, and anti‐inflammatory activity. The compounds show potent radical scavenging, strong protein‐denaturation inhibition surpassing diclofenac, and favorable docking against DHPS, myeloperoxidase, COX‐2, and ...
Mlis Belete +5 more
wiley +1 more source
Photoinduced cleavage of plasmid DNA in the presence of pterin
Pteridines, 2000 The photoinduced cleavage of plasmid DNA by UV -A light in the presence of pterin was investigated. Electrophoretic analysis of the irradiated plasmid pUCI8 in the presence of pterin showed that UV light of 350 nm induced the transformation of a ...
Lorente Carolina +5 more
doaj +1 more source
Quantification of Live Bacterial Sensing for Chemotaxis and Phagocytosis and of Macropinocytosis
Frontiers in Cellular and Infection Microbiology, 2018 Initial immunological defense mechanisms to pathogen invasion rely on innate pathways of chemotaxis and phagocytosis, original to ancient phagocytes. Although chemotaxis has been well-studied in mammalian and model systems using purified chemoattractants
Netra P. Meena, Alan R. Kimmel
doaj +1 more source
PLoS Genetics, 2021 Birds exhibit striking variation in eye color that arises from interactions between specialized pigment cells named chromatophores. The types of chromatophores present in the avian iris are lacking from the integument of birds or mammals, but are ...
Pedro Andrade +8 more
doaj +1 more source