Metabolic Processes Preserved as Biosignatures in Iron-Oxidizing Microorganisms: Implications for Biosignature Detection on Mars [PDF]
Iron-oxidizing bacteria occupy a distinct environmental niche. These chemolithoautotrophic organisms require very little oxygen (when neutrophilic) or outcompete oxygen for access to Fe(II) (when acidophilic).
Emerson, David +3 more
core +1 more source
Chemical Modifications of Globular Proteins Phototriggered by an Endogenous Photosensitizer [PDF]
, 2019 [EN] The main goal of the present work was to investigate the damages photoinduced by pterin (Ptr), an endogenous photosensitizer present in human skin under pathological conditions, on a globular protein such as ubiquitin (Ub).
Dántola, M. Laura +6 more
core +2 more sources
Evidence for corrin biosynthesis in the last universal common ancestor
The FEBS Journal, Volume 292, Issue 4, Page 827-850, February 2025.Cobalamin biosynthesis can be traced back to the last universal common ancestor. After a stage of chemical evolution of the acetyl‐CoA pathway, the enzymatic synthesis of cobalamin evolved, allowing life to be independent of the insoluble solid‐state catalysts that tethered primordial CO2 assimilation to the Earth's crust, suggesting a role for corrin ...
Luca D. Modjewski +5 more
wiley +1 more source
Degeneration of Rat Retina is Paralleled by an Imbalance of the Redox Mechanism of Pteridines
Pteridines, 1996 The RCS rat suffers from a genetic degeneration of retinal cell We have examined the pattern of oxidized and reduced monapterin and biopterin in retinas from RCS retinas and controls.
Cremer-Bartels Gertrud
doaj +1 more source
Flight initiation distance differs among eumelanin‐based color morphs in feral pigeons
Journal of Zoology, Volume 325, Issue 2, Page 115-123, February 2025.Animals facing anthropogenic activities usually exhibit phenotypic responses. Variation in melanin‐based coloration is associated with many phenotypic traits, including behavior, and may be associated with variation in tolerance to human proximity. We found that white feral pigeons had a lower Flight Initiation Distance (allowing closer proximity to ...
A. Frantz +4 more
wiley +1 more source
Mechanism of Substrate Activation by Tryptophan Hydroxylase: A Computational Study
ChemistryEurope, Volume 3, Issue 1, January 13, 2025.Density functional theory calculations are presented on large cluster models of tryptophan hydroxylase. The work shows that substrates are tightly bound and low‐energy pathways were obtained for a covalently‐bound iron‐BH4 complex. However, the rate‐determining step in the overall reaction cycle is the aromatic attack by iron(IV)‐oxo on tryptophan ...
Thirakorn Mokkawes, Sam P. de Visser
wiley +1 more source
Molecular characterization of the genes encoding the tungsten-containing aldehyde ferredoxin oxidoreductase from Pyrococcus furiosus and formaldehyde ferredoxin oxidoreductase from Thermococcus litoralis [PDF]
, 1995 The hyperthermophilic archaea Pyrococcus furiosus and Thermococcus litoralis contain the tungstoenzymes aldehyde ferredoxin oxidoreductase, a homodimer, and formaldehyde ferredoxin oxidoreductase, a homotetramer.
Adams, Michael W. W. +5 more
core +2 more sources
Characterization of Underivatized Pterins by Laser Desorption Fourier Transfonn Mass Spectrometry
Pteridines, 1993 Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)+ and (M + K)+ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more
Jacobson K. Bruce, Hettich Robert L.
doaj +1 more source
Photochemical formation of a fluorescent thymidine-pterin adduct in DNA [PDF]
, 2018 [EN] The photochemistry of the DNA biomacromolecule is an issue of paramount importance as it is part of the etiology of skin cancer development, being ultraviolet sunlight radiation the most relevant environmental carcinogen.
Estébanez, Sandra +6 more
core +2 more sources
Oxidation of biomolecules photosensitized by pterin derivatives [PDF]
, 2020 La importancia biológica y médica de las reacciones fotosensibilizadas se relaciona principalmente con su participación en los procesos involucrados en el desarrollo de cáncer de piel y de terapias fotodinámicas para el tratamiento del cáncer e ...
Dantola, Maria Laura +4 more
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