Results 61 to 70 of about 1,610 (169)
Inactivation of tyrosinase photoinduced by pterin
Biochemical and Biophysical Research Communications, 2012 Tyrosinase catalyzes in mammals the first and rate-limiting step in the biosynthesis of the melanin, the main pigment of the skin. Pterins, heterocyclic compounds able to photoinduce oxidation of DNA and its components, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder in which the protection against UV ...
Dantola, Maria Laura +2 more
openaire +3 more sources
The Scientific World Journal, Volume 2026, Issue 1, 2026.The focus of recent research has been on developing natural medicines. Natural substances of the Annona reticulata Linn. plant, which belongs to the Annonaceae family, have medicinal uses. The antibacterial, insecticidal, and antidiarrheal properties of Annona reticulata Linn.
Tasnia Binte Bari Kabbo +4 more
wiley +1 more source
Degeneration of Rat Retina is Paralleled by an Imbalance of the Redox Mechanism of Pteridines
Pteridines, 1996 The RCS rat suffers from a genetic degeneration of retinal cell We have examined the pattern of oxidized and reduced monapterin and biopterin in retinas from RCS retinas and controls.
Cremer-Bartels Gertrud
doaj +1 more source
Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives
ChemPlusChem, Volume 90, Issue 12, December 10, 2025.Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley +1 more source
Pterin Metabolism In Haemodialysis Patients
Pteridines, 1989 Patients undertaking maintenance haemodialysis may develop a variety of neurological disorders, the most serious of which is aluminium induced encephalopathy.
Altmann Paul +5 more
doaj +1 more source
Characterization of Underivatized Pterins by Laser Desorption Fourier Transfonn Mass Spectrometry
Pteridines, 1993 Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)+ and (M + K)+ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more
Jacobson K. Bruce, Hettich Robert L.
doaj +1 more source
Mechanistic Study of ROS-photogeneration by Pterin
Pteridines, 2011 Pterins are widespread in biological systems and possess photosensitizing activities. In the present study, the photosensitization mechanism of acid form of pterin (PTA) and basic form of pterin (PTB) is investigated by means of density functional theory
Ji Hong-Fang, Shen Liang
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Pteridines, 2002 Neopterin, 7,8-dihydroneopterin and 5,6,7,8-terahydroneopterm are secreted by human macrophages after activation by interferon-γ. The biological stability of the reduced pterins is less than one hour and therefore distinctly lower than that of neopterin.
Horejsi Renate +3 more
doaj +1 more source
eLife, 2017 Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors.
Hyun Bong Park +4 more
doaj +1 more source
Theoretical study on the relative energies of cationic pterin tautomers
Pteridines, 2015 Pterins are heterocyclic molecules of biological importance that contain several basic sites. These molecules can be protonated in aqueous solution resulting in a wide variety of structures that differ in their site of protonation and tautomeric form. In
Nekkanti Sindhura, Martin Christopher B.
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