Results 61 to 70 of about 2,236 (202)

Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase

, 1998
Nitric oxide synthases (NOS) are homodimeric enzymes that NADPH-dependently convert L-arginine to nitric oxide and L-citrulline. Interestingly, all NOS also require (6R)-5,6,7,8-tetrahydro-L-biopterin (H4Bip) for maximal activity although the mechanism ...
Meinecke, Matthias, Hofmann, Heinrich, Prestwich, Glenn D., Bernhardt, Manfred, Groehn, Viola, Schmidt, Harald H. H. W., Weeger, Monika, Pfleiderer, Wolfgang, Köster, Sandra, Frey, Armin, Marecak, Dale M., Reif, Andreas, Bömmel, Heike M., Fröhlich, Lothar G., La, Mylinh, Ghisla, Sandro, Kotsonis, Peter   +16 more
core   +1 more source

Mechanism of photooxidation of folic acid sensitized by unconjugated pterins [PDF]

, 2010
Folic acid, or pteroyl-L-glutamic acid (PteGlu), is a precursor of coenzymes involved in the metabolism of nucleotides and amino acids. PteGlu is composed of three moieties: a 6-methylpterin (Mep) residue, a p-aminobenzoic acid (PABA) residue, and a ...
Giménez, Carlos Sebastián, Peter R. Ogilby, Thomas, Andrés Héctor, Carlos S. Gimenez, Carolina Lorente, Andrés H. Thomas, Ogilby, Peter R., Denofrio, María Paula, Lorente, Carolina, Dántola, María Laura, M. Laura Dántola, Zurbano, Beatriz N., Beatriz Zurbano, M. Paula Denofrio   +13 more
core   +1 more source

Chemical Profiling and In Vitro Assessment of Antioxidant and Antimicrobial Properties of Algerian Erica arborea L. Extracts, Strengthened by Molecular Modeling Analysis

ChemistryOpen, Volume 15, Issue 8, August 2026.
Erica arborea L. from Algeria was valorized via chemical profiling and bioactivity assessment. The EtOAc extract showed the highest levels of polyphenols, flavonoids, and flavonols. It exhibited strong antioxidant (ABTS•+, DPPH•, FRAP) and antibacterial activity (S. aureus, B. subtilis).
Amina Bramki, Ouided Benslama, Fatima Zohra Makhlouf, Anna Andolfi, Zineb Mokhbi, Selsabile Nedjaoum, Chawki Bensouici, Maria Michela Salvatore, Marco Masi   +8 more
wiley   +1 more source

INVESTIGATION OF PTERINS BY LIQUID CHROMATOGRAPHY/ELECTROCHEMISTRY

, 1984
The pterins are a family of nitrogenous heterocyclic compounds which serve as cofactors to several hydroxylase enzymes. Although a reduced pterin is required for the hydroxylation of several amino acids intimately involved in brain function, the exact ...
LUNTE, CRAIG EDWARD
core   +1 more source

Testing for the Presence of Photobionts in Eucypris virens (Crustacea: Ostracoda) Green Valves

Freshwater Biology, Volume 71, Issue 8, August 2026.
ABSTRACT Crustaceans exhibit a wide range of organic pigments with different colorations and functions. However, little is known about the origin and function of the characteristic green pigmentation that podocopid ostracods, and in particular Eucypris virens, exhibit in their valves.
Julio Cruz‐Vila, Alexandre Mestre, Antonio Picazo, Olivier Schmit, Ian Boomer, Antonio Camacho, Ferran Palero, Francesc Mesquita‐Joanes   +7 more
wiley   +1 more source

Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays

Molecules, 2019
Pteridine reductase 1 (PTR1) is a trypanosomatid multifunctional enzyme that provides a mechanism for escape of dihydrofolate reductase (DHFR) inhibition. This is because PTR1 can reduce pterins and folates.
Magambo Phillip Kimuda, Dustin Laming, Heinrich C. Hoppe, Özlem Tastan Bishop   +3 more
doaj   +1 more source

Pterin and folate salvage. Plants and Escherichia coli lack capacity to reduce oxidized pterins

, 2007
Dihydropterins are intermediates of folate synthesis and products of folate breakdown that are readily oxidized to their aromatic forms. In trypanosomatid parasites, reduction of such oxidized pterins is crucial for pterin and folate salvage.
Naponelli V., Gregory III J. F., Hanson A. D., Noiriel A.   +3 more
core   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2511-2547, August 2026.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Functional Stability and the Limits of 16S‐Based Inference in Serpentine Biocrusts

Ecological Research, Volume 41, Issue 4, July 2026.
Serpentine geochemistry and moisture regime shape bacterial biocrust communities in the Barberton Greenstone Belt, South Africa. While coarse taxonomic metrics (alpha and beta diversity) showed no significant differences, ASV‐level analyses revealed strong taxonomic shifts linked to soil chemistry and moisture, with numerous serpentine‐associated taxa ...
Danielle Botha, Sandra Barnard, Sarina Claassens, Stefan J. Siebert   +3 more
wiley   +1 more source