Results 61 to 70 of about 1,623 (169)

Age‐Dependent Variation in Blood Biopterin Peaks Following Oral Tetrahydrobiopterin Administration in Phenylketonuria

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT The correct diagnosis of tetrahydrobiopterin (BH4, sapropterin dihydrochloride)‐responsive phenylketonuria (PKU) and treatment with BH4 are important for prognosis and quality of life. We examined whether age affects biopterin bioavailability following oral BH4 administration in PKU and whether this influences BH4 responsiveness.
Kana Kitayama   +5 more
wiley   +1 more source

Degeneration of Rat Retina is Paralleled by an Imbalance of the Redox Mechanism of Pteridines

open access: yesPteridines, 1996
The RCS rat suffers from a genetic degeneration of retinal cell We have examined the pattern of oxidized and reduced monapterin and biopterin in retinas from RCS retinas and controls.
Cremer-Bartels Gertrud
doaj   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

open access: yesNew Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov   +16 more
wiley   +1 more source

Pterin Metabolism In Haemodialysis Patients

open access: yesPteridines, 1989
Patients undertaking maintenance haemodialysis may develop a variety of neurological disorders, the most serious of which is aluminium induced encephalopathy.
Altmann Paul   +5 more
doaj   +1 more source

A contribution to the chemistry of pterins [PDF]

open access: yesProceedings of the Royal Society of London. Series B - Biological Sciences, 1942
Abstract The experiments in this paper have been chiefly concerned with a derivative from pterins, the wing pigments of pierid butterflies. These pigments have become prominent of recent years, partly on account of the prolonged efforts (1925-41) of continental workers to determine their nature.
openaire   +1 more source

Characterization of Underivatized Pterins by Laser Desorption Fourier Transfonn Mass Spectrometry

open access: yesPteridines, 1993
Laser desorption FfMS provides a powerful method for examining the structures of underivatized pteridines. (M + Na)+ and (M + K)+ ions are generated by laser desorption and can be used to determine molecular weights. The negative ion spectra provide more
Jacobson K. Bruce, Hettich Robert L.
doaj   +1 more source

Mechanistic Study of ROS-photogeneration by Pterin

open access: yesPteridines, 2011
Pterins are widespread in biological systems and possess photosensitizing activities. In the present study, the photosensitization mechanism of acid form of pterin (PTA) and basic form of pterin (PTB) is investigated by means of density functional theory
Ji Hong-Fang, Shen Liang
doaj   +1 more source

Neopterin, Dihydroneopterin, Tetrahydroneopterin: Different Structures-Increasing Capacity Cleaving the Porphyrin in Heme Proteins

open access: yesPteridines, 2002
Neopterin, 7,8-dihydroneopterin and 5,6,7,8-terahydroneopterm are secreted by human macrophages after activation by interferon-γ. The biological stability of the reduced pterins is less than one hour and therefore distinctly lower than that of neopterin.
Horejsi Renate   +3 more
doaj   +1 more source

Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster

open access: yeseLife, 2017
Nonribosomal peptides represent a large class of metabolites with pharmaceutical relevance. Pteridines, such as pterins, folates, and flavins, are heterocyclic metabolites that often serve as redox-active cofactors.
Hyun Bong Park   +4 more
doaj   +1 more source

Theoretical study on the relative energies of cationic pterin tautomers

open access: yesPteridines, 2015
Pterins are heterocyclic molecules of biological importance that contain several basic sites. These molecules can be protonated in aqueous solution resulting in a wide variety of structures that differ in their site of protonation and tautomeric form. In
Nekkanti Sindhura, Martin Christopher B.
doaj   +1 more source

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