Results 51 to 60 of about 2,236 (202)
Inactivation of tyrosinase photoinduced by pterin
Biochemical and Biophysical Research Communications, 2012 Tyrosinase catalyzes in mammals the first and rate-limiting step in the biosynthesis of the melanin, the main pigment of the skin. Pterins, heterocyclic compounds able to photoinduce oxidation of DNA and its components, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder in which the protection against UV ...
Dantola, Maria Laura +2 more
openaire +3 more sources
Acta Crystallographica Section D, Volume 82, Issue 9, Page 1072-1081, September 2026.We report a room‐temperature serial synchrotron X‐ray crystallographic structural analysis of Nitratidesulfovibrio vulgaris formate dehydrogenase AB, an enzyme that reduces CO2 to formate.Metal‐dependent formate dehydrogenases (Fdhs) are a promising research target in efforts to mitigate climate change by developing active, efficient, selective and ...
Guilherme Vilela-Alves +7 more
wiley +1 more source
Tetrahydrobiopterin (Bh4) deficiencies: diagnosis and treatment
Acta Pediátrica de México, 2014 Tetrahydrobiopterin (BH4) is an enzyme cofactor of phenylalanine hydroxylase, tyrosine hydroxylase and tryptophan hydroxylase. Three different enzymes affect BH4 synthesis: guanosine triphosphate cyclohydrolase I (GTP CH 1), 6-piruvoil tetrahydropterin ...
Mercedes Martínez-Pardo
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Ultraviolet-induced fluorescent imaging for millipede taxonomy [PDF]
Research Ideas and Outcomes, 2017 Fluorescent imaging has been traditionally applied to cell biology, and more recently to entomology to capture microscopic images of insect anatomy. However, the technique has not been applied to the study of millipedes, most of which autofluoresce as a ...
Paul Marek
doaj +2 more sources
Occurrence of Pterin Pigments in Hymenoptera [PDF]
Nature, 1950 IT has been found that pterins exist in tissues of animals belonging to nearly all groups; their occurrence as pigments, however, is restricted to insects and cold-blooded vertebrates1,2. Among Lepidoptera, they are always present in the wing-scales of the Pieridae and appear to be a biochemical characteristic of that natural family3,4.
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Advanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.A Strecker‐type reaction of aromatic ortho‐diamines with various aldehydes and cyanide assembles the bicyclic amidine core of flavin‐derived heterocycles under mild conditions. Subsequent oxidation, radical or photochemical cyanation, carboxylation with CO2, and CO2‐mediated cyclization build the three‐ring alloxazine scaffold. This sequence provides a
Christian Held +2 more
wiley +1 more source
Developmental and Phenotypic Outcomes in Mild Phenylalanine Hydroxylase Deficiency
American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1814-1820, August 2026.ABSTRACT Benign hyperphenylalaninemia (bHPA) is defined as elevated phenylalanine (Phe) levels remaining ≤ 360 μmol/L (6 mg/dL) and not requiring medical intervention. Individuals with bHPA may demonstrate a rise in their Phe levels > 360 μmol/L, effectively developing a mild PKU phenotype requiring therapy to prevent neurocognitive complications. This
Aaron Williams +8 more
wiley +1 more source
7-Substituted pterins: Formation during phenylalanine hydroxylation in the absence of dehydratase
, 1990 Previously we described a new form of human hyperphenylalaninemia characterized by the formation of 7-substituted pterins. We present evidence strongly suggesting that the 7-substituted pterins are formed by rearrangement of 6-substituted pterins.
Rebrin, Igor +4 more
core +1 more source
Current Research in Food Science, 2021 Fluorescence spectroscopy coupled with chemometric tools is a powerful analytical method, largely used for rapid food quality and safety evaluations. However, its potential has not yet been explored in the novel food sector.
G. Rossi +3 more
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Nucleotide Metabolism in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source