Results 51 to 60 of about 2,236 (204)
Tetrahydrobiopterin (Bh4) deficiencies: diagnosis and treatment
Acta Pediátrica de México, 2014 Tetrahydrobiopterin (BH4) is an enzyme cofactor of phenylalanine hydroxylase, tyrosine hydroxylase and tryptophan hydroxylase. Three different enzymes affect BH4 synthesis: guanosine triphosphate cyclohydrolase I (GTP CH 1), 6-piruvoil tetrahydropterin ...
Mercedes Martínez-Pardo
doaj +1 more source
Ultraviolet-induced fluorescent imaging for millipede taxonomy [PDF]
Research Ideas and Outcomes, 2017 Fluorescent imaging has been traditionally applied to cell biology, and more recently to entomology to capture microscopic images of insect anatomy. However, the technique has not been applied to the study of millipedes, most of which autofluoresce as a ...
Paul Marek
doaj +2 more sources
Occurrence of Pterin Pigments in Hymenoptera [PDF]
Nature, 1950 IT has been found that pterins exist in tissues of animals belonging to nearly all groups; their occurrence as pigments, however, is restricted to insects and cold-blooded vertebrates1,2. Among Lepidoptera, they are always present in the wing-scales of the Pieridae and appear to be a biochemical characteristic of that natural family3,4.
openaire +2 more sources
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Sixteen indazole–sulfonamide hybrids exhibit species‐dependent antibacterial activity against E. coli and S. aureus, with the lead compound displaying an eightfold lower MIC than sulfathiazole against E. coli. Molecular docking against wild‐type and Sul1‐resistant dihydropteroate synthase identifies a candidate retaining binding affinity toward the ...
Romaisaa Boudza +8 more
wiley +1 more source
Legume Science, Volume 8, Issue 3, September 2026.ABSTRACT Cold plasma (CP), a nonthermal ionised gas rich in reactive oxygen and nitrogen species (RONS), has emerged as a sustainable technology for enhancing legume production and quality. This review summarises current advances in CP applications in legumes, focusing on seed germination, seedling vigour, nutrient enhancement, antinutrient reduction ...
Jannatul Ferdous +5 more
wiley +1 more source
7-Substituted pterins: Formation during phenylalanine hydroxylation in the absence of dehydratase
, 1990 Previously we described a new form of human hyperphenylalaninemia characterized by the formation of 7-substituted pterins. We present evidence strongly suggesting that the 7-substituted pterins are formed by rearrangement of 6-substituted pterins.
Rebrin, Igor +4 more
core +1 more source
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen +3 more
wiley +1 more source
Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase
, 1998 Nitric oxide synthases (NOS) are homodimeric enzymes that NADPH-dependently convert L-arginine to nitric oxide and L-citrulline. Interestingly, all NOS also require (6R)-5,6,7,8-tetrahydro-L-biopterin (H4Bip) for maximal activity although the mechanism ...
Meinecke, Matthias +16 more
core +1 more source
Mechanism of photooxidation of folic acid sensitized by unconjugated pterins [PDF]
, 2010 Folic acid, or pteroyl-L-glutamic acid (PteGlu), is a precursor of coenzymes involved in the metabolism of nucleotides and amino acids. PteGlu is composed of three moieties: a 6-methylpterin (Mep) residue, a p-aminobenzoic acid (PABA) residue, and a ...
Giménez, Carlos Sebastián +13 more
core +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Eight chalcone‐sulfonamide hybrids (12a–h) are synthesized via Claisen–Schmidt condensation and evaluated for antibacterial, antioxidant, and anti‐inflammatory activity. The compounds show potent radical scavenging, strong protein‐denaturation inhibition surpassing diclofenac, and favorable docking against DHPS, myeloperoxidase, COX‐2, and ...
Mlis Belete +5 more
wiley +1 more source