Results 41 to 50 of about 2,236 (202)
Unveiling Photodegradation and Photosensitization Mechanisms of Unconjugated Pterins
, 2023 Unconjugated pterins are ubiquitous molecules that participate in countless enzymatic processes and are potentially involved in the photosensitization of singlet oxygen, amino acids, and nucleotides.
Corral, Ines, +5 more
core +1 more source
Theoretical Study on the Relative Energies of Anionic Pterin Tautomers
Pteridines, 2009 Pterins exist as several tautomeric forms and behave as weak acids in aqueous solutions. Therefore, several acidbase equilibria may be present. For several pterin derivatives, the range of the experimental pKa lies in the range 6-8.
Soniat Michael, Martin Christopher B.
doaj +1 more source
Body coloration and mechanisms of colour production in Archelosauria: the case of deirocheline turtles [PDF]
Royal Society Open Science, 2019 Animal body coloration is a complex trait resulting from the interplay of multiple mechanisms. While many studies address the functions of animal coloration, the mechanisms of colour production still remain unknown in most taxa.
Jindřich Brejcha +7 more
doaj +1 more source
Pteridines XCVIII. Synthesis and Properties of 1-Methylpterins
Pteridines, 1993 A series of 1-methyl-pterin derivatives (6-13) have been synthesized by condensation and methylation reactions. The compounds have been characterized by elemental analyses, pKa deterimations and UV spectra.
Pfleiderer Wolfgang
doaj +1 more source
2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Small, EarlyView.Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
wiley +1 more source
Mechanism of photooxidation of folic acid sensitized by unconjugated pterins [PDF]
, 2022 Folic acid, or pteroyl-L-glutamic acid (PteGlu), is a precursor of coenzymes involved in the metabolism of nucleotides and amino acids. PteGlu is composed of three moieties: a 6-methylpterin (Mep) residue, a p-aminobenzoic acid (PABA) residue, and a ...
Denofrio, María Paula +6 more
core
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Sixteen indazole–sulfonamide hybrids exhibit species‐dependent antibacterial activity against E. coli and S. aureus, with the lead compound displaying an eightfold lower MIC than sulfathiazole against E. coli. Molecular docking against wild‐type and Sul1‐resistant dihydropteroate synthase identifies a candidate retaining binding affinity toward the ...
Romaisaa Boudza +8 more
wiley +1 more source
MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen +3 more
wiley +1 more source
Biochemistry and biosynthesis of insect pigments
European Journal of Entomology, 2014 The functional role and commercial importance of insect pigments have been studied for well over a century. They are classified into those synthesized by insects, which include anthraquinones, aphins, pterins, tetrapyrroles, ommochromes, melanins and ...
Gulsaz SHAMIM +3 more
doaj +1 more source
ChemistryOpen, Volume 15, Issue 9, September 2026.Eight chalcone‐sulfonamide hybrids (12a–h) are synthesized via Claisen–Schmidt condensation and evaluated for antibacterial, antioxidant, and anti‐inflammatory activity. The compounds show potent radical scavenging, strong protein‐denaturation inhibition surpassing diclofenac, and favorable docking against DHPS, myeloperoxidase, COX‐2, and ...
Mlis Belete +5 more
wiley +1 more source