Results 21 to 30 of about 1,610 (169)
The urinary biopterin in autism spectrum disorder
Pteridines, 2021 The aim of the study was to determine whether biopterin is present in significantly lower quantities in urine samples of patients with autism spectrum disorder (ASD) compared to healthy individuals.
Waligóra Aleksandra +4 more
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Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block
Pteridines, 2022 Pterins, such as folate and biopterin, and their derivatives hold significant importance given their biological relevance, as well as the numerous pterin-based inhibitors developed for targeting various biological targets. For this reason, pterins can be
Bennett Zachary +2 more
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Modulation of Free Radical Formation by Pterin Derivatives
Pteridines, 2004 All classes of pterins, fully reduced tetrahydropterins, aromatic pterins and dihydropterins have been investigated upon their effects on radical mediated reactions.
Karl Oettl +2 more
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The Journal of Infectious Diseases, 2021 Abstract Background Cerebral malaria (CM) pathogenesis remains incompletely understood. Having shown low systemic levels of tetrahydrobiopterin (BH4), an enzymatic cofactor for neurotransmitter synthesis, we hypothesized that BH4 and BH4-dependent neurotransmitters would likewise be low in ...
Matthew P Rubach +13 more
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Journal of Biological Chemistry, 1972 Abstract Qualitative and quantitative analyses for pterins (derivatives of 2-amino-4-hydroxypteridine) in human urine were carried out by an improved procedure which involved the use of two new weak ion exchangers, ECTEOLA-Sephadex and phospho-Sephadex.
T, Fukushima, T, Shiota
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Pterin determination in cerebrospinal fluid: state of the art
Pteridines, 2017 The analysis of pterins in the cerebrospinal fluid (CSF) is mandatory for the etiologic diagnosis of inborn errors of dopamine and serotonin metabolism.
Guibal Pierre +3 more
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Pteridines, 1999 A series of new 6-substituted 2,4-diaminopteridines (3-23) and pterins (26-43) have been synthesized by nucleophilic displacement reactions at the side chain of 6-bromomethyl-2,4-diaminopteridine (2) and 6- bromomethylpterin (25) using various types of 0-
Traub Hermann, Pfleiderer Wolfgang
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Exploring the scope of DBU-promoted amidations of 7-methoxycarbonylpterin
Beilstein Journal of Organic Chemistry, 2020 The synthetic utility of pterins is often hampered by the notorious insolubility of this heterocycle, slowing the development of medicinally relevant pteridine derivatives.
Anna R. Bockman, Jeffrey M. Pruet
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Journal of Biological Chemistry, 1959 Publisher Summary This chapter describes the bacterial pterin deaminase. In the standard assay, the mixture contains 0.05 ml of pterin carboxylic acid, 0.8 ml of phosphate buffer, and 0.02 to 0.15 ml of enzyme in a final volume of 1.0 ml. Incubation is carried out at 23° in a 1-ml Beckman quartz cuvette with a light path of 1.00 cm. Reaction is begun
B, LEVENBERG, O, HAYAISHI
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CSF Amino Acids, Pterins and Mechanism of the Ketogenic Diet
Pediatric Neurology Briefs, 2015 Investigators from Hospital Sant Joan de Deu, Barcelona, Spain, studied the relationship between the etiology of refractory childhood epilepsy, CSF neurotransmitters, pterins, and amino acids, and response to a ketogenic diet in 60 patients with ...
J. Gordon Millichap
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