Results 31 to 40 of about 1,610 (169)

Tryptophan oxidation photosensitized by pterin

Free Radical Biology and Medicine, 2013
Pterins are normal components of cells and they have been previously identified as good photosensitizers under UV-A irradiation, inducing DNA damage and oxidation of nucleotides. In this work, we have investigated the ability of pterin (Ptr), the parent compound of oxidized pterins, to photosensitize the oxidation of another class of biomolecules ...
Thomas, Andrés, Serrano, Mariana, Rahal, Virginie, Vicendo, Patricia, Claparols, Catherine, Oliveros, Esther, Lorente, Carolina   +6 more
openaire   +4 more sources

7‐Substituted pterins in humans with suspected pterin‐4a‐carbinolamine dehydratase deficiency [PDF]

European Journal of Biochemistry, 1992
A recently described new form of hyperphenylalaninemia is characterized by the excretion of 7‐substituted isomers of biopterin and neopterin and 7‐oxo‐biopterin in the urine of patients. It has been shown that the 7‐substituted isomers of biopterin and neopterin derive from L‐tetrahydrobiopterin and D‐tetrahydroneopterin and are formed during ...
Adler, Carmen, Rebrin, Igor, Haavik, Jan, Heizmann, Claus W., Blau, Nenad, Kuster, Thomas, Curtius, Hans-Christoph, Ghisla, Sandro   +7 more
openaire   +3 more sources

Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes

BMC Cardiovascular Disorders, 2018
Background Development of collateral circulation in coronary artery disease is cardio-protective. A key process in forming new blood vessels is attraction to occluded arteries of monocytes with their subsequent activation as macrophages. In patients from
Edward C. A. Marks, Tom M. Wilkinson, Chris M. Frampton, Lorraine Skelton, Anna P. Pilbrow, Tim G. Yandle, Chris J. Pemberton, Robert N. Doughty, Gillian A. Whalley, Chris J. Ellis, Richard W. Troughton, Maurice C. Owen, Neil R. Pattinson, Vicky A. Cameron, A. Mark Richards, Steven P. Gieseg, Barry R. Palmer   +16 more
doaj   +1 more source

Photosensitization of peptides and proteins by pterin derivatives

Pteridines, 2017
Proteins are one of the preferential targets of the photosensitized damaging effects of ultraviolet (UV) radiation on biological system. Pterins belong to a family of heterocyclic compounds, which are widespread in living systems and participate in ...
Dantola Maria Laura, Reid Lara O., Castaño Carolina, Lorente Carolina, Oliveros Esther, Thomas Andrés H.   +5 more
doaj   +1 more source

Theoretical Study on the Relative Energies of Anionic Pterin Tautomers

Pteridines, 2009
Pterins exist as several tautomeric forms and behave as weak acids in aqueous solutions. Therefore, several acidbase equilibria may be present. For several pterin derivatives, the range of the experimental pKa lies in the range 6-8.
Soniat Michael, Martin Christopher B.
doaj   +1 more source

Body coloration and mechanisms of colour production in Archelosauria: the case of deirocheline turtles [PDF]

Royal Society Open Science, 2019
Animal body coloration is a complex trait resulting from the interplay of multiple mechanisms. While many studies address the functions of animal coloration, the mechanisms of colour production still remain unknown in most taxa.
Jindřich Brejcha, José Vicente Bataller, Zuzana Bosáková, Jan Geryk, Martina Havlíková, Karel Kleisner, Petr Maršík, Enrique Font   +7 more
doaj   +1 more source

Developmental and Phenotypic Outcomes in Mild Phenylalanine Hydroxylase Deficiency

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Benign hyperphenylalaninemia (bHPA) is defined as elevated phenylalanine (Phe) levels remaining ≤ 360 μmol/L (6 mg/dL) and not requiring medical intervention. Individuals with bHPA may demonstrate a rise in their Phe levels > 360 μmol/L, effectively developing a mild PKU phenotype requiring therapy to prevent neurocognitive complications. This
Aaron Williams, Kristian Divin, Lindsay C. Burrage, William J. Craigen, Fernando Scaglia, Claudia Soler‐Alfonso, V. Reid Sutton, Kevin E. Glinton, Ronit Marom   +8 more
wiley   +1 more source

Pteridines XCVIII. Synthesis and Properties of 1-Methylpterins

Pteridines, 1993
A series of 1-methyl-pterin derivatives (6-13) have been synthesized by condensation and methylation reactions. The compounds have been characterized by elemental analyses, pKa deterimations and UV spectra.
Pfleiderer Wolfgang
doaj   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source