Results 201 to 210 of about 190,444 (265)

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen   +5 more
wiley   +1 more source

Protease‐mediated maturation of M‐PMV reverse transcriptase into a functional heterodimer

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Marina Kapisheva   +6 more
wiley   +1 more source

Clustering of Longitudinal Data: A Tutorial on a Variety of Approaches

open access: yesStatistical Analysis and Data Mining: An ASA Data Science Journal, Volume 19, Issue 1, February 2026.
ABSTRACT During the past two decades, methods for identifying groups with different trends in longitudinal data involving a single numeric outcome have become of increasing interest across many areas of research. To support researchers, we summarize the guidance from literature regarding the clustering of such data.
N. G. P. Den Teuling   +2 more
wiley   +1 more source

Reference charts for first‐trimester placental three‐dimensional fractional moving blood volume derived using OxNNet

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 2, Page 191-200, February 2026.
ABSTRACT Objective To establish a comprehensive reference range for first‐trimester placental three‐dimensional (3D) single‐vessel fractional moving blood volume (svFMBV) using the OxNNet toolkit, based on values observed in healthy pregnancies.
S. Mathewlynn   +11 more
wiley   +1 more source

The Scientific Case for Animal Models: A Perspective From Musculoskeletal Researchers

open access: yesFASEB BioAdvances, Volume 8, Issue 2, February 2026.
ABSTRACT The National Institutes of Health (NIH) has launched a major initiative to expand human‐based New Approach Methodologies (NAMs) in biomedical research and reduce reliance on animal models. While NAMs offer powerful complementary tools, animal‐based research remains indispensable in musculoskeletal science for understanding complex cellular and
Michael Hadjiargyrou   +4 more
wiley   +1 more source

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