Results 181 to 190 of about 73,900 (261)

Renal Phosphate Reabsorption in Humans Depends on at Least Three Distinct Transporters Unlike in Mice

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Aim Kidney excretion of phosphate is the gatekeeper of systemic phosphate homeostasis as evident from inborn and acquired diseases. Renal phosphate transporters are a promising target for phosphate‐lowering drugs, but molecular details of human kidney phosphate handling are largely unknown.
Ashley L. Fernandes, Laurine Lang, Jürgen Klar, Anja Giese, Alexander Ehrmann, Rupert Busch, Hannah Auwerx, Christoph Daniel, Nati Hernando, Isabel Rubio‐Aliaga, Carsten A. Wagner   +10 more
wiley   +1 more source

Clinical manifestations, progression and treatment of post-traumatic hydrocephalus accompanied by contralateral subdural effusion after decompressive craniectomy: a single-center retrospective study. [PDF]

Front Neurol
Qiu J, Yan Y, Liu W, Gao G.
europepmc   +1 more source

Disruption of Claudin‐2 and Trpv6 Results in Hypocalcemia, Hypercalciuria, and Altered Bone Microarchitecture in Mice

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Transepithelial calcium absorption occurs via a transcellular or paracellular pathway. The intestinal transcellular pathway relies, at least partially, on the apical calcium channel transient receptor potential vanilloid 6 (TRPV6), whereas paracellular calcium (re)absorption occurs through tight junction proteins, including claudin‐2 (CLDN2 ...
Harneet Kaur Bhullar, Amanda Lima Deluque, Debbie D. O'Neil, Wanling Pan, Michael R. Doschak, Henrik Dimke, R. Todd Alexander   +6 more
wiley   +1 more source

Hypercalcaemia After a Sunny Holiday. [PDF]

Cureus
Ferrie S, Malhotra P, Amal Calist A.
europepmc   +1 more source

PTH intakt [PDF]

, 2019
openaire   +1 more source

Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, Volume 183, Issue 16, Page 4512-4531, August 2026.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

Effects of Short-term High-dose Vitamin D Supplementation on Mineral Homeostasis in Healthy Young Adults. [PDF]

In Vivo
Králová M, Černá P, Mikolášová H, Jirásko M, Dědečková E, Kučera R, Pecen L.   +6 more
europepmc   +1 more source

Intraoperatives PTH [PDF]

, 2019
openaire   +1 more source

Evolving Pathology of Anaplastic Thyroid Carcinoma: Integrating Morphology, Immunohistochemistry, and Molecular Insights

Cancer Science, Volume 117, Issue 8, Page 2029-2039, August 2026.
Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley   +1 more source