Results 1 to 10 of about 21,221 (170)
Acta Biomedica Scientifica, 2021 Parathyroid hormone receptors PTH1R and PTH2R are poorly studied in the pathology of the vertebral column and may be involved in both ectopic ossification of the vertebral ligaments and fibrous growth of the extracellular matrix, as well as in other ...
L. V. Rodionova +2 more
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Molecular Mechanisms of Parathyroid Disorders in Chronic Kidney Disease
Metabolites, 2022 Secondary hyperparathyroidism (SHP) is a common complication of chronic kidney disease (CKD) that induces morbidity and mortality in patients. How CKD stimulates the parathyroid to increase parathyroid hormone (PTH) secretion, gene expression and cell ...
Alia Hassan +6 more
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Tctex-1 augments G protein-coupled receptor-mediated Gs signaling by activating adenylyl cyclase
Journal of Pharmacological Sciences, 2021 Proteins interacting with G protein-coupled receptors (GPCRs) can modulate signal transduction of these receptors. However, the regulatory mechanisms of the interacting proteins are diverse and largely unknown.
Masaki Saito +5 more
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Secretion of parathyroid hormone may be coupled to insulin secretion in humans
Endocrine Connections, 2020 Objective: Parathyroid hormone (PTH) is a key hormone in regulation of calcium homeostasis and its secretion is regulated by calcium. Secretion of PTH is attenuated during intake of nutrients, but the underlying mechanism(s) are unknown.
Marie Reeberg Sass +12 more
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Frontiers in Endocrinology, 2022 Hypercalcemia is a common complication in cancer patients Mainly caused by Parathyroid hormone-related protein (PTHrP) secretion and metastasis. Calcitriol secretion is a rare source of hypercalcemia in solid tumors, especially in gastrointestinal ...
Yiraldine Herrera-Martínez +22 more
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Bisphosphonate-resistant hypercalcemia in a rare case of paraneoplastic PTH secretion
Journal of Clinical and Translational Endocrinology Case Reports, 2022 Background/objective: To report a rare case of ectopic parathyroid hormone (PTH) secretion from poorly-differentiated adenocarcinoma and the lessons learned in management.
Anna Y. Groysman +4 more
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Медицинский совет, 2022 Currently, the incidence and prevalence of chronic kidney disease (CKD) are increasing annually worldwide, and clinical data show that CKD patients commonly experience relative vitamin D insufficiency or deficiency.
L. V. Egshatyan
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Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation. [PDF]
PLoS ONE, 2017 Receptor activity-modifying protein 2 (Ramp2) is a single-pass transmembrane protein that heterodimerizes with several family B G-protein coupled receptors to alter their function.
Mahita Kadmiel +4 more
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Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2021 Pseudohypoparathyroidism (PHP) is a heterogeneous group of hereditary disorders characterized by clinical and biological characteristics of resistance to parathyroid hormone (PTH) caused by impaired hormonal signalling via receptors that are coupled ...
Fabio Sippelli +5 more
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Challenges in differential diagnosis between primary and secondary forms of hyperparathyroidism
Ожирение и метаболизм, 2017 Hyperparathyroidism is a disease characterized by excessive secretion of parathyroid hormone (PTH) in the chief cells of parathyroid glands. There are three types of hyperparathyroidism: primary, secondary, and tertiary depending on the cause of this ...
Natalia G. Mokrysheva +3 more
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