Results 11 to 20 of about 39,335 (289)

Pseudohypoparathyroidism and its various phenotypes: three sisters with three different clinical presentations

open access: yesAtti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche, 2021
Pseudohypoparathyroidism (PHP) is a heterogeneous group of hereditary disorders characterized by clinical and biological characteristics of resistance to parathyroid hormone (PTH) caused by impaired hormonal signalling via receptors that are coupled ...
Fabio Sippelli   +5 more
doaj   +1 more source

Role of Calcimimetics in Treating Bone and Mineral Disorders Related to Chronic Kidney Disease

open access: yesPharmaceuticals, 2022
Renal osteodystrophy is common in patients with chronic kidney disease and end-stage renal disease and leads to the risks of fracture and extraosseous vascular calcification.
Yi-Chou Hou   +5 more
doaj   +1 more source

The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]

open access: yes, 2013
The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves   +3 more
core   +1 more source

Challenges in differential diagnosis between primary and secondary forms of hyperparathyroidism

open access: yesОжирение и метаболизм, 2017
Hyperparathyroidism is a disease characterized by excessive secretion of parathyroid hormone (PTH) in the chief cells of parathyroid glands. There are three types of hyperparathyroidism: primary, secondary, and tertiary depending on the cause of this ...
Natalia G. Mokrysheva   +3 more
doaj   +1 more source

Proteolytic Cleavage of the Extracellular Domain Affects Signaling of Parathyroid Hormone 1 Receptor

open access: yesFrontiers in Endocrinology, 2022
Parathyroid hormone 1 receptor (PTH1R) is a member of the class B family of G protein-coupled receptors, which are characterized by a large extracellular domain required for ligand binding.
Christoph Klenk   +7 more
doaj   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz   +3 more
wiley   +1 more source

Parathyroid diseases and animal models

open access: yesFrontiers in Endocrinology, 2012
Circulating calcium and phosphate are tightly regulated by 3 hormones: the active form of vitamin D (1,25-dihydroxyvitamin D), fibroblast growth factor (FGF)-23, and parathyroid hormone (PTH).
Yasuo eImanishi   +2 more
doaj   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek   +18 more
wiley   +1 more source

Parathyroid localization [PDF]

open access: yes, 1986
Twenty-nine consecutive patients with suspected primary hyperparathyroidism were examined preoperatively using ultrasound, sonographically guided fine needle aspiration, and aspirate immunostaining for PTH.
Borisch, B.   +7 more
core   +1 more source

Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: The Extracellular Calcium Receptor and an Innovative Medical Approach to Control Secondary Hyperparathyroidism by Calcimimetics

open access: yesJournal of Pharmacological Sciences, 2005
Circulating levels of calcium ion (Ca2+) are maintained within a narrow physiological range mainly by the action of parathyroid hormone (PTH) secreted from parathyroid cells.
Nobuo Nagano, Edward F. Nemeth
doaj   +1 more source

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