Results 11 to 20 of about 21,293 (242)

Role of Calcimimetics in Treating Bone and Mineral Disorders Related to Chronic Kidney Disease

Pharmaceuticals, 2022
Renal osteodystrophy is common in patients with chronic kidney disease and end-stage renal disease and leads to the risks of fracture and extraosseous vascular calcification.
Yi-Chou Hou, Cai-Mei Zheng, Hui-Wen Chiu, Wen-Chih Liu, Kuo-Cheng Lu, Chien-Lin Lu   +5 more
doaj   +1 more source

Parathyroid diseases and animal models

Frontiers in Endocrinology, 2012
Circulating calcium and phosphate are tightly regulated by 3 hormones: the active form of vitamin D (1,25-dihydroxyvitamin D), fibroblast growth factor (FGF)-23, and parathyroid hormone (PTH).
Yasuo eImanishi, Yuki eNagata, Masaaki eInaba   +2 more
doaj   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Receptor oligomerization: from early evidence to current understanding in class B GPCRs

Frontiers in Endocrinology, 2013
Dimerization or oligomerization of G protein-coupled receptors (GPCRs) are known to modulate receptor functions in terms of ontogeny, ligand-oriented regulation, pharmacological diversity, signal transduction and internalization.
Stephanie Yuen Lam Ng, Leo Tsz On Lee, Billy Kwok Chong Chow   +2 more
doaj   +1 more source

Proteolytic Cleavage of the Extracellular Domain Affects Signaling of Parathyroid Hormone 1 Receptor

Frontiers in Endocrinology, 2022
Parathyroid hormone 1 receptor (PTH1R) is a member of the class B family of G protein-coupled receptors, which are characterized by a large extracellular domain required for ligand binding.
Christoph Klenk, Leif Hommers, Leif Hommers, Leif Hommers, Martin J. Lohse, Martin J. Lohse, Martin J. Lohse, Martin J. Lohse   +7 more
doaj   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

BJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek, M. Almquist, A. O. Bergenfelz, T. J. Musholt, E. Nordenström, on behalf of the EUROCRINE® Council, M. Almquist, M. Barczynski, L. Brunaud, T. Clerici, M. H. Hansen, M. Iacobone, Ö. Makay, F. F. Palazzo, N. Muñoz‐Pérez, M. Raffaelli, P. Riss, S. van Slycke, M. R. Vriens   +18 more
wiley   +1 more source

Functional Proteins Involved in Regulation of Intracellular Ca2+ for Drug Development: The Extracellular Calcium Receptor and an Innovative Medical Approach to Control Secondary Hyperparathyroidism by Calcimimetics

Journal of Pharmacological Sciences, 2005
Circulating levels of calcium ion (Ca2+) are maintained within a narrow physiological range mainly by the action of parathyroid hormone (PTH) secreted from parathyroid cells.
Nobuo Nagano, Edward F. Nemeth
doaj   +1 more source

The role of Vitamin D in malaria

Journal of Infection in Developing Countries, 2015
An abnormal calcium-parathyroid hormone (PTH)-vitamin D axis has been reported in patients with malaria infection. A role for vitamin D in malaria has been suggested by many studies. Genetic studies have identified numerous factors that link vitamin D to
Khanh Vinh Quốc Luong, Lan Thi Hoàng Nguyen   +1 more
doaj   +1 more source

Parathyroid hormone and parathyroid hormone type-1 receptor accelerate myocyte differentiation [PDF]

Scientific Reports, 2014
The ZHTc6-MyoD embryonic stem cell line expresses the myogenic transcriptional factor MyoD under the control of a tetracycline-inducible promoter. Following induction, most of the ZHTc6-MyoD cells differentiate to myotubes. However, a small fraction does not differentiate, instead forming colonies that retain the potential for myocyte differentiation ...
Shigemi Kimura, Kowasi Yoshioka
openaire   +2 more sources

Acute salinity and temperature challenges during early development of zebrafish: Differential gene expression of PTHs, PTHrPs and their receptors

Aquaculture and Fisheries, 2017
Parathyroid hormone (pth), parathyroid hormone-related peptide (pthrp) and their receptors are involved in the regulation of calcium homeostasis in all vertebrates.
Yingying Jin, Zhaohui Lan, Gege Zhu, Weiqun Lu   +3 more
doaj   +1 more source