Results 31 to 40 of about 39,335 (289)
International Journal of Nephrology, 2012 Secondary hyperparathyroidism (s-HPT) in uremia is characterized by decreased expression in the parathyroids of calcium sensing (CaR) and vitamin D receptors (VDR).
Jacob Hofman-Bang +3 more
doaj +1 more source
Physiopathological Implications of 7TM Receptors [PDF]
, 2010 Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core +2 more sources
Positioning novel biologicals in CKD-mineral and bone disorders [PDF]
, 2017 Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian +5 more
core +1 more source
FGF23 Actions on Target Tissues—With and Without Klotho
Frontiers in Endocrinology, 2018 Fibroblast growth factor (FGF) 23 is a phosphaturic hormone whose physiologic actions on target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co-receptor that increases the binding affinity of FGF23 for FGFRs.
Beatrice Richter, Christian Faul
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionNaringenin, a peroxisome proliferator-activated receptor (PPAR) activator found in citrus fruits, upregulates markers of thermogenesis and insulin sensitivity in human adipose tissue.
Ann A. Coulter +8 more
doaj +1 more source
Parathyroid hormone acts as a pharmacological chaperone on the parathyroid hormone receptor
The FASEB Journal, 2008 Parathyroid hormone receptor (PTH1R) belongs to class B G‐protein‐coupled receptors and is the major regulator of extracellular calcium homeostasis. Binding of the native ligand parathyroid hormone (PTH) or biologically active peptide fragments of PTH to the receptor lead to the activation of Gs and Gq/G11 pathways with subsequent stimulation of ...
Christoph Klenk, Martin J. Lohse
openaire +1 more source
Advances in Difference Equations, 2017 Calcium signaling plays important physiological roles which range widely from activation of muscle, synaptic transmission, cell movement, fertilization, growth in the cell population, learning process and retention of memory, to saliva secretion. Calcium
Chontita Rattanakul, Yongwimon Lenbury
doaj +1 more source
Changes in Bone Metabolism and Structure in Primary Hyperparathyroidism
Acta Medica Bulgarica, 2020 Parathyroid hormone (PTH) is a key regulator of bone turnover. Depending on the duration of action, the hormone causes catabolic and anabolic effects by binding with specific receptors (PTHR1) in the bone.
Yankova I., Shinkov A., Kovatcheva R.
doaj +1 more source
The calcium-sensing receptor in inflammation: Recent updates
Frontiers in Physiology, 2022 The Calcium-Sensing Receptor (CaSR) is a member of the class C of G-proteins coupled receptors (GPCRs), it plays a pivotal role in calcium homeostasis by directly controlling calcium excretion in the kidneys and indirectly by regulating parathyroid ...
Luca Iamartino, Maria Luisa Brandi
doaj +1 more source
Neurological, psychological, and cognitive disorders in patients with chronic kidney disease on conservative and replacement therapy [PDF]
, 2016 Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients.
Aceto, Paola +15 more
core +1 more source