Results 51 to 60 of about 21,293 (242)

Pregnancy‐ and lactation‐associated osteoporosis: A position statement of the IAPM, IOF, ECTS, ESCEO, IMS, and EMAS

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a syndrome characterized by fragility fractures (most commonly vertebral, often multiple) occurring in late pregnancy or the early postpartum period. This position statement summarizes the current knowledge of PLO, and the recommended procedure for assessment, diagnosis and treatment ...
Peyman Hadji, Apostolos Athanasiadis, Maria‐Luisa Brandi, Marlene Chakhtoura, Manju Chandran, Frank Chervenak, Amos Grünebaum, Irene Lambrinoudaki, Willem F. Lems, Apostolos M. Mamopoulos, Eugene McCloskey, Rossella E. Nappi, Jessica Pepe, Jean‐Yves Reginster, René Rizzoli, Petra Stute, Şansın Tuzun, Amanda J. Vincent, Maria Belen Zanchetta, M. Carola Zillikens, Ioannis Kyvernitakis   +20 more
wiley   +1 more source

Effects of Parathyroid Hormone on Immune Function

Clinical and Developmental Immunology, 2010
Parathyroid hormone (PTH) function as immunologic mediator has become interesting with the recent usage of PTH analogue (teriparatide) in the management of osteoporosis.
Abdallah Sassine Geara, Mario R. Castellanos, Claude Bassil, Georgia Schuller-Levis, Eunkue Park, Marianne Smith, Michael Goldman, Suzanne Elsayegh   +7 more
doaj   +1 more source

Parental Origin of Gsα Inactivation Differentially Affects Bone Remodeling in a Mouse Model of Albright Hereditary Osteodystrophy

JBMR Plus, 2022
Albright hereditary osteodystrophy (AHO) is caused by heterozygous inactivation of GNAS, a complex locus that encodes the alpha‐stimulatory subunit of heterotrimeric G proteins (Gsα) in addition to NESP55 and XLαs due to alternative first exons.
Patrick McMullan, Peter Maye, Qingfen Yang, David W. Rowe, Emily L. Germain‐Lee   +4 more
doaj   +1 more source

Application of current enteral nutrition support recommendations to infants born less than 750 grams or less than 25 weeks' gestation: A critical review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Clinicians face a paucity of evidence‐based recommendations for provision of enteral nutrition in infants born <750 g or <25 weeks’ gestation, termed “nano‐preterm.” Current enteral nutrition recommendations for extremely low birth weight infants may not be broadly applicable to nano‐preterm infants due to physiological and developmental ...
Mar Romero‐Lopez, Mamta Naik, Teresa Hartman, Ann Anderson‐Berry, Melissa Thoene   +4 more
wiley   +1 more source

Sclerostin antibodies as novel anabolic therapy for osteoporosis

Остеопороз и остеопатии, 2019
Osteoporosis medications are dividedinto two groups: those inhibiting bone resorption and formation (bisphosphonates and denosumab), and those stimulating bone formation i.e. having an anabolic effect. The latter include teriparatide, parathyroid hormone
Elizaveta O. Mamedova, Tatiana A. Grebennikova, Zhanna E. Belaya, Liudmila Y. Rozhinskaya   +3 more
doaj   +1 more source

Characterizing the Epithelial Transcriptome of Type‐2 High Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
Brian Cameron, Jeffanie Gayoso, Christina Dorismond, Ping Li, Mason Krysinski, Rakesh Chandra, Justin Turner, Naweed Chowdhury   +7 more
wiley   +1 more source

Receptor oligomerization in family B1 of G-protein-coupled receptors: Focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity

Frontiers in Endocrinology, 2012
The superfamily of the seven transmembrane G-protein-coupled receptors (7TM/GPCRs) is the largest family of membrane-associated receptors. GPCRs are involved in the pathophysiology of numerous human diseases, and they constitute an estimated 30-40 % of ...
Sarah Norklit Roed, Anne eOrgaard, Rasmus eJorgensen, Pierre eDe Meyts   +3 more
doaj   +1 more source

Understanding and Addressing Delays in Endocrine Surgery: Insights From a Mixed‐Methods Study and a Pilot Educational Intervention

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Delays in endocrine surgical care contribute to adverse events, patient dissatisfaction, and mortality. Communication is an overlooked contributor. This study identified multi‐level drivers of delay and piloted a provider‐focused intervention. Methods We conducted an IRB‐approved mixed‐methods study.
Stella Kim, Maxwell Foote, Sophia Zhang, Audrey Twyford, Abigail Fox, Jennifer E. Rosen   +5 more
wiley   +1 more source

Pharmacokinetics of evocalcet in secondary hyperparathyroidism patients receiving hemodialysis: first-in-patient clinical trial in Japan

Clinical Pharmacology: Advances and Applications, 2018
Takashi Shigematsu,1 Ryutaro Shimazaki,2 Masafumi Fukagawa,3 Tadao Akizawa4 On behalf of the Evocalcet Study Group 1Department of Nephrology, Wakayama Medical University, Wakayama, Japan; 2R&D Division, Kyowa Hakko Kirin Co., Ltd., Chiyoda-ku, Tokyo,
Shigematsu T, Shimazaki R, Fukagawa M, Akizawa T   +3 more
doaj  

Safety, Pharmacokinetics, and Pharmacodynamics of SHR6508, a Calcium-Sensing Receptor Agonist, in Maintenance Hemodialysis Patients With Secondary Hyperparathyroidism: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 1 Study

Kidney Medicine
Rationale & Objective: Secondary hyperparathyroidism (SHPT) is a common health problem among patients receiving maintenance hemodialysis. SHR6508, an allosteric modulator of calcium-sensing receptors, was developed to reduce parathyroid hormone ...
Sijia Li, Li Fan, Rui Yan, Bicheng Liu, Linghui Zhou, Guangqun Xing, Wei Zhao, Zunsong Wang, Deguang Wang, Min Zhang, Qing Zhu, Li Xing, Dong Sun, Deyong Fan, Jue Mei, Hao Zhang, Hong Jiang, Haochang Du, Rui Chen, Xinyu Yang, Xue Yang, Kunming Li, Xin Zhang, Zhiming Ye, Xueqing Yu   +24 more
doaj   +1 more source