Results 161 to 170 of about 92,751 (208)
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Journal of the American Society of Nephrology, 2022
Full-length parathyroid hormone (PTH 1–84) is crucial for the regulation of calcium and phosphate homeostasis and bone remodeling. PTH 1–84 is metabolized into various PTH fragments, which are measured with varying levels of efficiency by PTH immunoassays.
Candice Z. Ulmer +4 more
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Full-length parathyroid hormone (PTH 1–84) is crucial for the regulation of calcium and phosphate homeostasis and bone remodeling. PTH 1–84 is metabolized into various PTH fragments, which are measured with varying levels of efficiency by PTH immunoassays.
Candice Z. Ulmer +4 more
openaire +2 more sources
Annales d'Endocrinologie, 2015
Even if the first assay for parathyroid hormone (PTH) was published in the early 1960s, its determination remains a challenge even today. Indeed, in the circulation, PTH is present in its active form (PTH 1-84), but many PTH fragments can also be present.
CAVALIER, Etienne +3 more
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Even if the first assay for parathyroid hormone (PTH) was published in the early 1960s, its determination remains a challenge even today. Indeed, in the circulation, PTH is present in its active form (PTH 1-84), but many PTH fragments can also be present.
CAVALIER, Etienne +3 more
openaire +3 more sources
Clinical calcium, 2005
Injectable forms of parathyroid hormone (PTH) and its N-terminal fragments are bone anabolic agents proven by randomized clinical trials. Alternate delivery forms of parathyroid hormone are under clinical or preclinical studies, including nasal, transdermal, and pulmonary formulations of PTH (1-34).
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Injectable forms of parathyroid hormone (PTH) and its N-terminal fragments are bone anabolic agents proven by randomized clinical trials. Alternate delivery forms of parathyroid hormone are under clinical or preclinical studies, including nasal, transdermal, and pulmonary formulations of PTH (1-34).
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Parathyroid Hormone (PTH) Suppresses Rat PTH/PTH-Related Protein Receptor Gene Promoter
Biochemical and Biophysical Research Communications, 2001Parathyroid hormone (PTH) regulates osteoblasts via a G protein-linked PTH/PTH-related protein (PTHrP) receptor. PTH effects on PTH/PTHrP receptor gene expression were studied in UMR 106 osteoblast-like cells. In heterogeneous nuclear RNA and Northern analysis, PTH suppressed PTH/PTHrP receptor transcription.
T, Kawane +3 more
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Comprehensive Physiology, 2016
ABSTRACT PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles in the maintenance of calcium and phosphate homeostasis as well as the development and maintenance of bone health.
Syed Jalal, Khundmiri +2 more
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ABSTRACT PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles in the maintenance of calcium and phosphate homeostasis as well as the development and maintenance of bone health.
Syed Jalal, Khundmiri +2 more
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2015
Parathyroid hormone (PTH) is an 84-amino acid polypeptide endocrine hormone that is produced by the parathyroid glands and secreted into the circulation in response to low calcium levels.
Giancarlo Isaia, Margherita Marchetti
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Parathyroid hormone (PTH) is an 84-amino acid polypeptide endocrine hormone that is produced by the parathyroid glands and secreted into the circulation in response to low calcium levels.
Giancarlo Isaia, Margherita Marchetti
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PTH Receptors and Skeletal Resistance to PTH Action
2020Secondary hyperparathyroidism (SHPT) is an integral component of chronic kidney disease-mineral and bone disorder (CKD-MBD). Many factors have been associated with its development and progression, but the presence of skeletal or calcemic resistance to the action of PTH in CKD has often gone unnoticed.
Jordi Bover +5 more
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PTH Treatment in Hypoparathyroidism
Current Drug Safety, 2011Hypoparathyroidism (HypoPT) is one of the few major hormone deficiency diseases that are not usually treated with the missing hormone. Bovine parathyroid hormone (PTH) has been purified and used as experimental treatment, as long back as in 1928 by Fuller Albright. Treatment, however, was abolished mainly because of antibody formation and costs.
Tanja, Sikjaer +2 more
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Endocrinology, 1994
Recent data have shown that PTH down-regulation of its receptor on opossum kidney (OK) cells is not associated with any change in the steady state level of the PTH/PTH-related peptide (PTHrP) receptor messenger RNA. For analysis of down-regulation of the PTH/PTHrP receptor in OK cells, the present work uses a specific receptor anti-serum, SR-2, that is
A B, Abou-Samra +5 more
openaire +3 more sources
Recent data have shown that PTH down-regulation of its receptor on opossum kidney (OK) cells is not associated with any change in the steady state level of the PTH/PTH-related peptide (PTHrP) receptor messenger RNA. For analysis of down-regulation of the PTH/PTHrP receptor in OK cells, the present work uses a specific receptor anti-serum, SR-2, that is
A B, Abou-Samra +5 more
openaire +3 more sources
Journal of endocrinological investigation, 2012
At least 2 different types of cells, hematopoietic and mesenchymal, are present in the adult bone marrow, in addition to endothelial cells. Hematopoietic and mesenchymal cells are believed to originate from hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC), respectively.
M. Ohishi, E. Schipani
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At least 2 different types of cells, hematopoietic and mesenchymal, are present in the adult bone marrow, in addition to endothelial cells. Hematopoietic and mesenchymal cells are believed to originate from hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC), respectively.
M. Ohishi, E. Schipani
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