Results 171 to 180 of about 92,751 (208)

PTH(1–84)/PTH(7–84): a balance of power

American Journal of Physiology-Renal Physiology, 2006
This review considers many new basic and clinical aspects of parathyroid hormone (PTH). We focus especially on the identification of PTH fragments and how they may relate to renal failure, diagnosis, and treatment of secondary hyperparathyroidism and renal osteodystrophy.
Peter A, Friedman, William G, Goodman
openaire   +2 more sources

PTHrP, PTH, and the PTH/PTHrP receptor in endochondral bone development

Birth Defects Research Part C: Embryo Today: Reviews, 2003
AbstractEndochondral bone development is a fascinating story of proliferation, maturation, and death. An understanding of this process at the molecular level is emerging. In particular, significant advances have been made in understanding the role of parathyroid‐hormone‐related peptide (PTHrP), parathyroid hormone (PTH), and the PTH/PTHrP receptor in ...
Ernestina, Schipani, Sylvain, Provot
openaire   +2 more sources

Kinetics of PTH Metabolism and PTH Fragments in Chronic Renal Failure

2015
Distribution and metabolic degradation of bPTH was studied in man after infusion of 400 U bPTH and blood sampling up to 2h. Disappearance rates of intact 1-84 bPTH, carboxyl- and amino-regional peptides were calculated for healthy subjects (n = 12); patients suffering from moderate (GFR 15--30 ml/min, n = 4) and advanced (GFR less than or equal to 10 ...
N, Lustenberger, R, Hehrmann, H, Jüppner, G, Delling, R D, Hesch   +4 more
openaire   +2 more sources

[Significance of a new PTH assay (the comparison between whole-PTH and intact-PTH assay)].

Clinical calcium, 2005
It has been shown that intact-PTH assay measures not only full-length biologically active PTH with 84 amino acids, but also some PTH fragments such as (7-84) PTH. Whole-PTH assay is a new method believed to react only with (1-84) PTH. Because circulatory concentrations of various fragments of PTH are very high especially in patients with secondary ...
Nobuaki, Ito, Seiji, Fukumoto
openaire   +1 more source

PTH-like Peptides.

2004
The present invention relates to peptides that are parathyroid hormone (PTH) analogs, useful for the treatment of hypoparathyroidism and diseases characterized by bone mass reduction, such as osteoporosis, and for stimulating bone repair or favoring the engraftment of a bone implant; to the pharmaceutical compositions comprising these PTH-like peptides
CAPORALE, ANDREA, Fiori, N., SCHIEVANO, ELISABETTA, MAMMI, STEFANO, PEGGION, EVARISTO, Chorev, M., Wittelsberger, A.   +6 more
openaire   +5 more sources

Pth 1-84, Pth fragments and bone turnover

American Journal of Kidney Diseases, 2003
Hartmut H, Malluche, Marie-Claude, Monier-Faugere   +1 more
openaire   +2 more sources

Physiological and Pharmacological Roles of PTH and PTHrP in Bone Using Their Shared Receptor, PTH1R

Endocrine Reviews, 2021
T John Martin, Natalie A Sims, Ego Seeman   +2 more
exaly  

PTH

2011
openaire   +2 more sources

[PTH preparations].

Nihon rinsho. Japanese journal of clinical medicine, 2016
Parathyroid hormone(PTH) is essential for maintaining serum calcium level. PTH increases serum calcium partly by enhancing bone resorption. Therefore, persistent excessive actions of PTH result in cortical bone loss by increased bone resorption. In contrast, intermittent injections of PTH preparations increase trabecular bone mainly by enhancing bone ...
openaire   +1 more source

[PTH/PTH-related peptide].

Nihon rinsho. Japanese journal of clinical medicine, 2000
H, Tahara, Y, Nishizawa
openaire   +1 more source