Results 211 to 220 of about 73,900 (261)
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2015
Parathyroid hormone (PTH) is an 84-amino acid polypeptide endocrine hormone that is produced by the parathyroid glands and secreted into the circulation in response to low calcium levels.
Giancarlo Isaia, Margherita Marchetti
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Parathyroid hormone (PTH) is an 84-amino acid polypeptide endocrine hormone that is produced by the parathyroid glands and secreted into the circulation in response to low calcium levels.
Giancarlo Isaia, Margherita Marchetti
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PTH Receptors and Skeletal Resistance to PTH Action
2020Secondary hyperparathyroidism (SHPT) is an integral component of chronic kidney disease-mineral and bone disorder (CKD-MBD). Many factors have been associated with its development and progression, but the presence of skeletal or calcemic resistance to the action of PTH in CKD has often gone unnoticed.
Jordi Bover +5 more
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Annales d'Endocrinologie, 2015
Even if the first assay for parathyroid hormone (PTH) was published in the early 1960s, its determination remains a challenge even today. Indeed, in the circulation, PTH is present in its active form (PTH 1-84), but many PTH fragments can also be present.
CAVALIER, Etienne +3 more
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Even if the first assay for parathyroid hormone (PTH) was published in the early 1960s, its determination remains a challenge even today. Indeed, in the circulation, PTH is present in its active form (PTH 1-84), but many PTH fragments can also be present.
CAVALIER, Etienne +3 more
openaire +3 more sources
Clinical calcium, 2005
Injectable forms of parathyroid hormone (PTH) and its N-terminal fragments are bone anabolic agents proven by randomized clinical trials. Alternate delivery forms of parathyroid hormone are under clinical or preclinical studies, including nasal, transdermal, and pulmonary formulations of PTH (1-34).
openaire +3 more sources
Injectable forms of parathyroid hormone (PTH) and its N-terminal fragments are bone anabolic agents proven by randomized clinical trials. Alternate delivery forms of parathyroid hormone are under clinical or preclinical studies, including nasal, transdermal, and pulmonary formulations of PTH (1-34).
openaire +3 more sources
Annales d'Endocrinologie, 2021
Cardiovascular diseases remain the leading cause of non-communicable chronic diseases, are related to high morbidity and mortality and are associated to a huge impact on healthcare budgets. Biomarkers play an important role for the diagnosis and prognosis of cardiovascular diseases and are recognized tools for value-based care. Parathyroid hormone (PTH)
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Cardiovascular diseases remain the leading cause of non-communicable chronic diseases, are related to high morbidity and mortality and are associated to a huge impact on healthcare budgets. Biomarkers play an important role for the diagnosis and prognosis of cardiovascular diseases and are recognized tools for value-based care. Parathyroid hormone (PTH)
openaire +2 more sources
Parathyroid Hormone (PTH) Suppresses Rat PTH/PTH-Related Protein Receptor Gene Promoter
Biochemical and Biophysical Research Communications, 2001Parathyroid hormone (PTH) regulates osteoblasts via a G protein-linked PTH/PTH-related protein (PTHrP) receptor. PTH effects on PTH/PTHrP receptor gene expression were studied in UMR 106 osteoblast-like cells. In heterogeneous nuclear RNA and Northern analysis, PTH suppressed PTH/PTHrP receptor transcription.
T, Kawane +3 more
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Endocrinology, 1994
Recent data have shown that PTH down-regulation of its receptor on opossum kidney (OK) cells is not associated with any change in the steady state level of the PTH/PTH-related peptide (PTHrP) receptor messenger RNA. For analysis of down-regulation of the PTH/PTHrP receptor in OK cells, the present work uses a specific receptor anti-serum, SR-2, that is
A B, Abou-Samra +5 more
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Recent data have shown that PTH down-regulation of its receptor on opossum kidney (OK) cells is not associated with any change in the steady state level of the PTH/PTH-related peptide (PTHrP) receptor messenger RNA. For analysis of down-regulation of the PTH/PTHrP receptor in OK cells, the present work uses a specific receptor anti-serum, SR-2, that is
A B, Abou-Samra +5 more
openaire +3 more sources
Comprehensive Physiology, 2016
ABSTRACT PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles in the maintenance of calcium and phosphate homeostasis as well as the development and maintenance of bone health.
Syed Jalal, Khundmiri +2 more
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ABSTRACT PTH and Vitamin D are two major regulators of mineral metabolism. They play critical roles in the maintenance of calcium and phosphate homeostasis as well as the development and maintenance of bone health.
Syed Jalal, Khundmiri +2 more
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PTH Treatment in Hypoparathyroidism
Current Drug Safety, 2011Hypoparathyroidism (HypoPT) is one of the few major hormone deficiency diseases that are not usually treated with the missing hormone. Bovine parathyroid hormone (PTH) has been purified and used as experimental treatment, as long back as in 1928 by Fuller Albright. Treatment, however, was abolished mainly because of antibody formation and costs.
Sikjaer, Tanja; id_orcid 0000-0002-9074-9570 +2 more
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Journal of endocrinological investigation, 2012
At least 2 different types of cells, hematopoietic and mesenchymal, are present in the adult bone marrow, in addition to endothelial cells. Hematopoietic and mesenchymal cells are believed to originate from hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC), respectively.
M. Ohishi, E. Schipani
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At least 2 different types of cells, hematopoietic and mesenchymal, are present in the adult bone marrow, in addition to endothelial cells. Hematopoietic and mesenchymal cells are believed to originate from hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC), respectively.
M. Ohishi, E. Schipani
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