Results 121 to 130 of about 3,009 (161)

Elucidation of the Hemostatic and Anti-Inflammatory Effects of Walnut Shell Ethanol Extract by Network Pharmacology and Experimental Verification. [PDF]

Food Sci Nutr
He Y, Zhao W, Sun Y, Ma L, Li C, Zheng X, Feng Z, Guo H, Qin L, Zhang Y.   +9 more
europepmc   +1 more source

Bioinformatics analysis reveals shared molecular pathways for relationship between ulcerative colitis and primary sclerosing cholangitis. [PDF]

Genomics Inform
Jalali P, Rezaee M, Yaghoobi A, Piroozkhah M, Zabihi MR, Aliyari S, Salehi Z.   +6 more
europepmc   +1 more source

Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene. [PDF]

Cell Mol Gastroenterol Hepatol
Spalinger MR, Sanati G, Chatterjee P, Hai R, Li J, Santos AN, Nordgren TM, Tremblay ML, Eckmann L, Hanson E, Scharl M, Wu X, Boland BS, McCole DF.   +13 more
europepmc   +1 more source

A Prognostic Nomogram Based on an Immunogenic Cell Death and Endoplasmic Reticulum Stress-Related Gene Signature for Ovarian Cancer. [PDF]

Int J Womens Health
Lu X, Zhu L, Zhang X, Yang N, Zhu Z, Liu Q.   +5 more
europepmc   +1 more source

The synergistic pathogenic mechanism of <i>Brucella melitensis</i> M5-90 effector protein BspC in regulating host cell apoptosis, inflammation and oxidative stress. [PDF]

J Med Microbiol
Yin S, Li L, Zhu L, He J, Liu Y, Xi L, Mao H, Deng X, Yi J, Zhang J.   +9 more
europepmc   +1 more source

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Association Between the PTPN2 Gene and Crohnʼs Disease

Inflammatory Bowel Diseases, 2013
Although genome-wide association studies (GWAS) and subsequent meta-analyses have confirmed associations between the PTPN2 (protein tyrosine phosphatase, nonreceptor type 2) gene and Crohn's disease (CD), the potential causal variants remain unidentified.
, Emile Levy, Guy Grimard
exaly   +5 more sources

PTPN2: Advances and perspectives in cancer treatment potential and inhibitor research

International Journal of Biological Macromolecules
Protein tyrosine phosphatase non-receptor 2 (PTPN2) is a well-established protein tyrosine phosphatase (PTP) that counterbalances protein tyrosine kinases (PTKs) activity by dephosphorylating tyrosine residues. Accumulating evidence demonstrates that dysregulated PTPN2 expression or activity regulates cancer biology, drives immune evasion, and confers ...
Yaru, Zhang, Xiaocui, Shuai, Yang, Lei, Tingnan, Ma, Tao, Yuan, Shaomin, Zhu, Lei, Zhong   +6 more
exaly   +3 more sources