Results 101 to 110 of about 3,009 (161)

Phosphatases: An undervalued class of antitumor drug targets. [PDF]

Acta Pharm Sin B
Wang M, Zhan P, Song Y.
europepmc   +1 more source

Interaction between haploinsufficiency of PTPN2 and patient microbiome promotes autoimmune arthritis in mice. [PDF]

J Autoimmun
Sendo S, Vela AJ, Ro M, Thiruppathy D, Wilkinson EL, Zhao Z, Hsieh WC, Yang S, Coras R, Bergot AS, Guma M, Nguyen A, McBride DA, Devkota S, Thomas R, Shah NJ, Svensson MND, Zengler K, Stanford SM, Bottini N.   +19 more
europepmc   +1 more source

Uncovering the individual immunotherapeutic roles of PTPN1 and PTPN2 in T cells during dual inhibition. [PDF]

iScience
Perez-Quintero LA, Poirier AJ, Feng CH, Martinez-Cordova Z, Aubry I, Carli C, Kamyabiazar S, Pacis A, Zolotarov Y, Pike KA, Delisle JS, Tremblay ML.   +11 more
europepmc   +1 more source

PTPN12 is a novel biomarker associated with genomic instability, therapeutic potentials, and immunomodulator in colorectal cancer. [PDF]

Front Pharmacol
Qian S, Gong H, Zhang P, Pan Y, Zhang B, Liu Q.   +5 more
europepmc   +1 more source

The type 1 diabetes candidate genes PTPN2 and BACH2 regulate the IFN-α-induced crosstalk between JAK/STAT and MAPKs pathways in human beta cells. [PDF]

EBioMedicine
Roca-Rivada A, Oliveira JG, Martin-Vazquez E, Coomans de Brachène A, Yi X, Costa-Júnior JM, Zimath PL, Van Goethem F, Pattou F, Kerr-Conte J, Buemi A, Mourad NI, Eizirik DL.   +12 more
europepmc   +1 more source

Phosphatases in tumor cell immune escape: a perspective based on the camouflage, coercion, cytoprotection. [PDF]

Front Cell Dev Biol
Zhang C, Qiu X, Shi W, Zhu S.
europepmc   +1 more source

Multi-omics identification of a programmed cell death-related signature and potential target P4HB for bladder cancer based on a 101-combination machine learning and experimental validation. [PDF]

Clin Exp Med
Cao Y, Li C, Hua Y, Wu T, Shen Q, Lin Z, Huang Y.   +6 more
europepmc   +1 more source

In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma. [PDF]

Nature
Knudsen NH, Escobar G, Korell F, Kienka T, Nobrega C, Anderson S, Cheng AY, Zschummel M, Armstrong A, Bouffard A, Kann MC, Goncalves S, Pope HW, Pezeshki M, Rojas A, Suermondt JSMT, Phillips M, Berger TR, Park S, Salas-Benito D, Darnell EP, Birocchi F, Leick MB, Larson RC, Doench JG, Sen D, Yates KB, Manguso RT, Maus MV.   +28 more
europepmc   +1 more source

Spatiotemporally delivery of Cas9 ribonucleoprotein/DNAzyme logic systems using near-infrared upconversion nanomachine for precise immunotherapy. [PDF]

Acta Pharm Sin B
Chen C, Du S, Lu Q, Shen X, Ding S, Qu L, Gao Y, Yin Z, Li Z, Song Y, Han X.   +10 more
europepmc   +1 more source

PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice. [PDF]

Int J Mol Sci
Lei H, Shawki A, Santos AN, Canale V, Manz S, Crawford MS, Chatterjee P, Spalinger MR, Scharl M, McCole DF.   +9 more
europepmc   +1 more source