Results 31 to 40 of about 352,027 (304)

A Fast Algorithm for Robust Regression with Penalised Trimmed Squares

, 2009
The presence of groups containing high leverage outliers makes linear regression a difficult problem due to the masking effect. The available high breakdown estimators based on Least Trimmed Squares often do not succeed in detecting masked high leverage ...
A Giloni, AC Atkinson, AC Atkinson, AS Hadi, C Agostinelli, CW Coakley, D Gervini, D Peña, D Peña, DM Hawkins, DM Hawkins, DM Hawkins, DM Sebert, G Zioutas, G Zioutas, G. Zioutas, J Agulló, JF Gentleman, L. Pitsoulis, LM Li, LS Pitsoulis, M Salibian-Barrera, MS Bazaraa, N Billor, N Billor, N Billor, O Hössjer, PJ Rousseeuw, PJ Rousseeuw, PJ Rousseeuw, PJ Rousseeuw, RJ Rousseeuw, TA Feo, VJ Yohai, VJ Yohai   +34 more
core   +2 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Enhanced PAPR reduction in NOMA systems using modified SLM and PTS techniques for power-efficient 5G and beyond networks

Open Engineering
This paper presents an enhanced framework for peak-to-average power ratio (PAPR) reduction in non-orthogonal multiple access (NOMA) systems using modified Selective Mapping (m-SLM) and Partial Transmit Sequence (m-PTS) algorithms.
Kumar Arun, Gaur Nishant, Nanthaamornphong Aziz   +2 more
doaj   +1 more source

Mesenchymal Stem Cells Expressing Vasoactive Intestinal Peptide Ameliorate Symptoms in a Model of Chronic Multiple Sclerosis

Cell Transplantation, 2013
Multiple sclerosis (MS) is a severe debilitating disorder characterized by progressive demyelination and axonal damage of the central nervous system (CNS).
Marién Cobo, Per Anderson, Karim Benabdellah, Miguel G. Toscano, Pilar Muñoz, Angélica García-Pérez, Iván Gutierrez, Mario Delgado, Francisco Martin   +8 more
doaj   +1 more source

RNA Aptamers as Molecular Tools to Study the Functionality of the Hepatitis C Virus CRE Region

Molecules, 2015
Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, functional RNA domains, many of them with unknown roles for the consecution of the viral cycle. Such genomic domains are candidate therapeutic targets. This
Alba Fernández-Sanlés, Beatriz Berzal-Herranz, Rodrigo González-Matamala, Pablo Ríos-Marco, Cristina Romero-López, Alfredo Berzal-Herranz   +5 more
doaj   +1 more source

Microwave-Assisted Formation of Ternary Inclusion Complex of Pterostilbene

Pharmaceuticals, 2023
Pterostilbene (PTS) is a naturally occurring phytoalexin. PTS displays limited water solubility, which consequently results in its diminished oral bioavailability.
Yousef A. Bin Jardan, Abdul Ahad, Mohammad Raish, Abdullah M. Al-Mohizea, Fahad I. Al-Jenoobi   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

NCI-MATCH Arms N & P: Phase II study of PI3K beta inhibitor GSK2636771 in patients (pts) with cancers (ca) with PTEN mutation/deletion (mut/del) or PTEN protein loss [PDF]

, 2018
Background: The NCI-MATCH trial is the largest national study (1173 sites) for ptswith relapsed/ refractory solid tumors, lymphomas and myeloma, which assigns tar-geted therapies based on individual tumor molecular alterations detected using theadapted ...
Arteaga, C., Chen, A. P., Conley, B. A., Doyle, L. A., Flaherty, K. T., Hamilton, S. R., Harris, L. N., Janku, F., Jegede, O., Konstantinopoulos, P., Li, S., McShane, L. M., Meric-Bernstam, F., Mitchell, E. P, O\u27Dwyer, P. J., Patton, D., Puhalla, S. L., Rubinstein, L. V., Williams, P. M., Zwiebel, J. A.   +19 more
core   +1 more source

Coalgebraic Trace Semantics for Continuous Probabilistic Transition Systems [PDF]

, 2013
Coalgebras in a Kleisli category yield a generic definition of trace semantics for various types of labelled transition systems. In this paper we apply this generic theory to generative probabilistic transition systems, short PTS, with arbitrary ...
Barbara König, Henning Kerstan, Universität Duisburg-essen Duisburg   +2 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source