Results 31 to 40 of about 69,752 (265)
Cell Transplantation, 2013 Multiple sclerosis (MS) is a severe debilitating disorder characterized by progressive demyelination and axonal damage of the central nervous system (CNS).
Marién Cobo +8 more
doaj +1 more source
RNA Aptamers as Molecular Tools to Study the Functionality of the Hepatitis C Virus CRE Region
Molecules, 2015 Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, functional RNA domains, many of them with unknown roles for the consecution of the viral cycle. Such genomic domains are candidate therapeutic targets. This
Alba Fernández-Sanlés +5 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Methyl siloxanes are identified as emerging persistent toxic compounds and the ecological environment risks of these compounds have been caused of great concern worldwide.
Weijun Guo +6 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Pediatric Trauma Severity Assessment and Prognosis Using Automated Scoring Systems
The EuroBiotech JournalBackground: Trauma remains one of the leading causes of morbidity and mortality in the pediatric population. Early assessment of injury severity is essential for timely triage, risk stratification, and clinical decision-making.
Dachev D. +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Representation of "Disease" by mothers of adolescent childhood cancer survivors
Психология и Психотерапия Семьи, 2018 To describe representations of "disease" in families with adolescent childhood cancer survivors. Method: Participants were 8 mothers with experience of encounter of childhood cancer and 7 mothers without it. They chose one picture from TAT as association
Julia Bykhovets, Phd, Lina Kogan-Lerner
doaj
Journal of NanobiotechnologyMicroRNAs (miRNAs) have been recognised as potential biomarkers due to their specific expression patterns in different biological tissues and their changes in expression under pathological conditions. MicroRNA-122 (miR-122) is a vertebrate-specific miRNA
Agustín Robles-Remacho +10 more
doaj +1 more source
Microwave-Assisted Formation of Ternary Inclusion Complex of Pterostilbene
Pharmaceuticals, 2023 Pterostilbene (PTS) is a naturally occurring phytoalexin. PTS displays limited water solubility, which consequently results in its diminished oral bioavailability.
Yousef A. Bin Jardan +4 more
doaj +1 more source