Results 41 to 50 of about 103,920 (315)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

SLM and PTS peak-power reduction of OFDM signals without side information

, 2005
Selected mapping (SLM) and partial transmit sequence\ud (PTS) are well-known techniques for peak-power reduction\ud in orthogonal frequency-division multiplexing (OFDM).
Jayalath, Dhammika, Tellambura, Chintha
core   +1 more source

PTS-prosessin luominen kohdeyrityksen kiinteistömanagereille [PDF]

, 2020
Tämän insinöörityön tavoitteena oli luoda Caverion Suomi Oy:n kiinteistömanagereille yhtenäinen pitkän tähtäimen suunnitelma (PTS)-prosessi. Yritys toivoi saavansa insinöörityön tuloksena yleispätevän PTS-prosessimallin.
Laitonen, Laura
core  

Enhanced PAPR reduction in NOMA systems using modified SLM and PTS techniques for power-efficient 5G and beyond networks

Open Engineering
This paper presents an enhanced framework for peak-to-average power ratio (PAPR) reduction in non-orthogonal multiple access (NOMA) systems using modified Selective Mapping (m-SLM) and Partial Transmit Sequence (m-PTS) algorithms.
Kumar Arun, Gaur Nishant, Nanthaamornphong Aziz   +2 more
doaj   +1 more source

Mesenchymal Stem Cells Expressing Vasoactive Intestinal Peptide Ameliorate Symptoms in a Model of Chronic Multiple Sclerosis

Cell Transplantation, 2013
Multiple sclerosis (MS) is a severe debilitating disorder characterized by progressive demyelination and axonal damage of the central nervous system (CNS).
Marién Cobo, Per Anderson, Karim Benabdellah, Miguel G. Toscano, Pilar Muñoz, Angélica García-Pérez, Iván Gutierrez, Mario Delgado, Francisco Martin   +8 more
doaj   +1 more source

RNA Aptamers as Molecular Tools to Study the Functionality of the Hepatitis C Virus CRE Region

Molecules, 2015
Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, functional RNA domains, many of them with unknown roles for the consecution of the viral cycle. Such genomic domains are candidate therapeutic targets. This
Alba Fernández-Sanlés, Beatriz Berzal-Herranz, Rodrigo González-Matamala, Pablo Ríos-Marco, Cristina Romero-López, Alfredo Berzal-Herranz   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

An intelligent genetic algorithm for PAPR reduction in a multi-carrier CDMA wireless system

, 2008
— A novel intelligent genetic algorithm (GA), called Minimum Distance guided GA (MDGA) is proposed for peak-average-power ratio (PAPR) reduction based on partial transmit sequence (PTS) scheme in a synchronous Multi-Carrier Code Division Multiple Access (
Chen, HH, Song, Y., Yang Zhang, Yonghua Song, Qiang Ni, Ni, Q, Ni, Q., Zhang, Y, Song, Y, Chen, H.H., Hsiao-Hwa Chen, Zhang, Y.   +11 more
core   +1 more source

Microwave-Assisted Formation of Ternary Inclusion Complex of Pterostilbene

Pharmaceuticals, 2023
Pterostilbene (PTS) is a naturally occurring phytoalexin. PTS displays limited water solubility, which consequently results in its diminished oral bioavailability.
Yousef A. Bin Jardan, Abdul Ahad, Mohammad Raish, Abdullah M. Al-Mohizea, Fahad I. Al-Jenoobi   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source