Results 51 to 60 of about 352,027 (304)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Key steps and methods in the experimental design and data analysis of highly multi-parametric flow and mass cytometry

Computational and Structural Biotechnology Journal, 2020
High-dimensional, single-cell cell technologies revolutionized the way to study biological systems, and polychromatic flow cytometry (FC) and mass cytometry (MC) are two of the drivers of this revolution.
Paulina Rybakowska, Marta E. Alarcón-Riquelme, Concepción Marañón   +2 more
doaj   +1 more source

Preventing Violence in the Homes of Military Families [PDF]

, 2013
The wars in Iraq and Afghanistan, Operation Iraqi Freedom and Operation Enduring Freedom (OIF/OEF), have demanded unprecedented service at every level of the U.S. Army, Air Force, Navy, and Marines. For the first time in our military history, active duty,

core  

Statistical analysis of 22 public transport networks in Poland [PDF]

, 2005
Public transport systems in 22 Polish cities have been analyzed. Sizes of these networks range from N=152 to N=2881. Depending on the assumed definition of network topology the degree distribution can follow a power law or can be described by an ...
C. von Ferber, J. A. Hołyst, J. F. F. Mendes, J. Sienkiewicz, Janusz A. Hołyst, Julian Sienkiewicz, R. Pastor-Satorras, U. Brandes   +7 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Representation of "Disease" by mothers of adolescent childhood cancer survivors

Психология и Психотерапия Семьи, 2018
To describe representations of "disease" in families with adolescent childhood cancer survivors. Method: Participants were 8 mothers with experience of encounter of childhood cancer and 7 mothers without it. They chose one picture from TAT as association
Julia Bykhovets, Phd, Lina Kogan-Lerner
doaj  

Synthetic DNA immunotherapy in biochemically relapsed prostate cancer [PDF]

, 2018
Background: INO-5150 (PSA and PSMA) +/- INO-9012 (IL-12), a synthetic DNA immunotherapy, was assessed for safety, immunogenicity and efficacy in biochemically recurrent prostate cancer patients (pts).
Appleman, L. J., Bagarazzi, M. L., Bhatt, K., Cheng, H., Csiki, I., Garcia, J., Heath, E. I., Kelly, W., Kraynyak, K., Lee, J., Liu, L., McMullan, T., Morrow, M., Nordquist, L. T., Rosencranz, S., Sacchetta, B., Shore, N., Tagawa, S. T., Tutrone, R., Whang, Y.   +19 more
core   +1 more source

A comparison of classical scheduling approaches in power-constrained block-test scheduling [PDF]

, 2000
Classical scheduling approaches are applied here to overcome the problem of unequal-length block-test scheduling under power dissipation constraints. List scheduling-like approaches are proposed first as greedy algorithms to tackle the fore mentioned ...
Muresan, Valentin, Muresan, Valentina, Vladutiu, M., Wang, Xiaojun   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Mitigating gas migration with eutectic bismuth alloy plugs

Petroleum Research
Gas migration is an important concern to address in oil wells, especially in those that are to be abandoned. Stopping a gas leakage is not a simple task, and this can be particularly detrimental when setting a cement plug, as the migrated gas can ...
Lewaa Hmadeh, Andriani Manataki, Marcelo Anunciação Jaculli, Behzad Elahifar, Sigbjørn Sangesland   +4 more
doaj   +1 more source