Results 51 to 60 of about 118,480 (299)

Click chemistry-based dual nanosystem for microRNA-122 detection with single-base specificity from tumour cells

open access: yesJournal of Nanobiotechnology
MicroRNAs (miRNAs) have been recognised as potential biomarkers due to their specific expression patterns in different biological tissues and their changes in expression under pathological conditions. MicroRNA-122 (miR-122) is a vertebrate-specific miRNA
Agustín Robles-Remacho   +10 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

การศึกษาการลำดับคำของส่วนขยายกริยาและคำกริยาภาษาจีนโดยใช้หลักการลำดับของเวลา (PTS) [PDF]

open access: yes
This study addresses the challenge of understanding the word order of verb modifiers and verbs in Chinese, an area complicated by numerous intricate rules that often hinder learners.
นุสิทธิ์ชัยการ, อภิรักษ์   +1 more
core   +1 more source

PT-PT Synthetic Speech Detection

open access: yes
Recent developments in the field of artificial intelligence (AI) have led to the creation of powerful generative models. These models have demonstrated such capabilities that it becomes nearly impossible for a human to distinguish between generated and human utterances, between synthetic and natural speech.
Rafael Geraldo dos Santos   +2 more
openaire   +4 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Principle of PTS and SPLICEFINDER.

open access: yes, 2013
(A) The PTS reaction scheme. B) Schematic representation of the PTS cassette amplification and insertion procedure. The point of integration into the target gene (gene of interest; GOI) is controlled by the sequence of the PCR primers used for PTS ...
Joachim Zettler (452888)   +6 more
core   +1 more source

Reduced complexity PTS and new phase sequences for SLM to reduce PAP of an OFDM signal [PDF]

open access: yes, 2000
This paper presents a simplified version of partial transmit sequences (PTS) and a new scheme for selected mapping sequences to reduce peak-to-average power ratio (PAP) of an OFDM signal.
Wu, H.   +2 more
core   +1 more source

Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis

open access: yesMolecular Therapy: Nucleic Acids, 2013
Lung pathology in cystic fibrosis is linked to dehydration of the airways epithelial surface which in part results from inappropriately raised sodium reabsorption through the epithelial sodium channel (ENaC).
Kenneth L Clark   +23 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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