Results 71 to 80 of about 118,480 (299)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Pitkän tähtäimen suunnittelu (PTS)

open access: yes, 2021
Tiivistelmä. Tämän kandidaatintyön tavoitteena on avata kiinteistöjen pitkän tähtäimen suunnitteluprosessia (PTS-prosessi) ja löytää siinä hyödynnettäviä toimintamalleja.
Sinda, P. (Perttu)
core  

Development of bismuth-based solutions for well plugging and abandonment: A review

open access: yesPetroleum Research
Plugging and abandonment (P&A) is a crucial step of the well life cycle. Regardless of how long one stretches the productive life of a well, P&A operations will have to be carried out eventually.
Lewaa Hmadeh   +3 more
doaj   +1 more source

¿Hacia una aceleración de la automatización y el “fin del trabajo”?

open access: yesCuadernos de Economía Crítica, 2022
A partir del libro Automatización y el futuro del trabajo, de Aaron Benanav, y la polémica entre este autor y Kim Moody, abordamos en este artículo la discusión de cómo vienen impactando los desarrollos tecnológicos como la inteligencia artificial y la ...
Esteban Mercatante
doaj  

The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes

open access: yesMolecular Therapy: Nucleic Acids, 2018
Integration-defective lentiviral vectors (IDLVs) have become an important alternative tool for gene therapy applications and basic research. Unfortunately, IDLVs show lower transgene expression as compared to their integrating counterparts. In this study,
Sabina Sánchez-Hernández   +15 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

A model including CD15, ACE2 and age efficiently predicts COVID-19 severity

open access: yesScientific Reports
The COVID-19 pandemic presents a spectrum of clinical outcomes ranging from respiratory conditions to cardiovascular complications that challenge management and resource allocation. Identification of early predictive biomarkers that are easy to detect is
Sergio Cuenca-López   +7 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Exosomal miRNA profile as complementary tool in the diagnostic and prediction of treatment response in localized breast cancer under neoadjuvant chemotherapy

open access: yesBreast Cancer Research, 2019
Background Breast cancer patients under neoadjuvant chemotherapy includes a heterogeneous group of patients who eventually develop distal disease, not detectable by current methods.
Alba Rodríguez-Martínez   +13 more
doaj   +1 more source

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