Results 71 to 80 of about 69,752 (265)

Crosstalk Between Autophagy and Oxidative Stress in Hematological Malignancies: Mechanisms, Implications, and Therapeutic Potential

Antioxidants
Autophagy is a fundamental cellular process that maintains homeostasis by degrading damaged components and regulating stress responses. It plays a crucial role in cancer biology, including tumor progression, metastasis, and therapeutic resistance ...
Antonio José Cabrera-Serrano, José Manuel Sánchez-Maldonado, Carmen González-Olmedo, María Carretero-Fernández, Leticia Díaz-Beltrán, Juan Francisco Gutiérrez-Bautista, Francisco José García-Verdejo, Fernando Gálvez-Montosa, José Antonio López-López, Paloma García-Martín, Eva María Pérez, Pedro Sánchez-Rovira, Fernando Jesús Reyes-Zurita, Juan Sainz   +13 more
doaj   +1 more source

Isolation of Murine Adipose Tissue-derived Mesenchymal Stromal Cells (mASCs) and the Analysis of Their Proliferation in vitro

Bio-Protocol, 2015
Mesenchymal stromal cells (MSCs) are non-hematopoietic, perivascular cells which support hematopoiesis and are thought to participate in tissue repair in vivo.
Per Anderson, Ana Carrillo-Gálvez, Francisco Martín   +2 more
doaj   +1 more source

Enhanced field-driven domain wall motion in Pt/Co/Pt and Pt/C068B32/Pt strips

Applied Physics Letters, 2011
It is now commonly accepted that materials exhibiting high perpendicular magnetic anisotropy are excellent candidates for devices based on current-induced domain-wall (DW) motion. A major hindrance of these materials however, is that they exhibit strong DW pinning.
Lavrijsen, R., Verheijen, M.A., Barcones Campo, B., Kohlhepp, J.T., Swagten, H.J.M., Koopmans, B.   +5 more
openaire   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

pH-Sensitive Porphyrin Metal-Organic Frameworks for Controlled Delivery of Para-Toluenesulfonamide and Photodynamic Cancer Therapy

Drug Design, Development and Therapy
Wei Zhou,1 Fan Feng,2 Jieli Zhang,3 Shuang Cao,4 Yunzhi Zhou,3 Yanming Li1 1Department of Pulmonary and Critical Care Medicine, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, Beijing,
Zhou W, Feng F, Zhang J, Cao S, Zhou Y, Li Y   +5 more
doaj  

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Individuals with Multi‐Joint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data from the Canadian Longitudinal Study on Aging

Arthritis Care &Research, Accepted Article.
Objective Test the hypothesis that multi‐joint osteoarthritis would modify the relation between time and frailty progression, where more affected joints would lead to larger declines over 6‐years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

Alichondrichlorin, a Novel Chlorohydrin‐Containing Natural Product With Tumoral Cytotoxic Activity Isolated From the Planctomycetota Bacterium Alienimonas chondri LzC2T

Microbial Biotechnology
To address the on‐going need for chemical novelty and the limited information on Planctomycetota secondary metabolism, we focused on exploring the recently isolated marine planctomycetal strain Alienimonas chondri LzC2T to uncover its potential ...
Inês R. Vitorino, José D. N. Santos, Gloria Crespo, Ignacio Pérez‐Victoria, Jesús Martín, Lorena Rodriguez, Maria C. Ramos, Teresa P. Martins, Pedro N. Leão, Francisca Vicente, Vítor Vasconcelos, Olga M. Lage, Fernando Reyes   +12 more
doaj   +1 more source

Clinical characteristics and concordance of anti‐MDA5 autoantibodies: A multicentre Australian study

Arthritis Care &Research, Accepted Article.
Objectives In Australia, anti‐MDA5 antibodies are exclusively tested by line immunoblot assay (LIA). The clinical concordance of a LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies.
Syed B Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source