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Frontiers in Endocrinology, 2020 Delayed puberty is a common reason of pediatric endocrinological consultation. It is often a self-limited (or constitutional) condition with a strong familial basis. The type of inheritance is variable but most commonly autosomal dominant.
Adalgisa Festa +3 more
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The Genetic Basis of Delayed Puberty
Frontiers in Endocrinology, 2019 Delayed pubertal onset has many etiologies, but on average two-thirds of patients presenting with late puberty have self-limited (or constitutional) delayed puberty. Self-limited delayed puberty often has a strong familial basis.
Sasha R. Howard
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Exposure to heavy metals, bisphenol A, and phthalates: Implications for precocious or delayed puberty. [PDF]
PLoS ONEThis study examined the associations between exposure to heavy metals, bisphenol A (BPA), and phthalates and precocious or delayed puberty. This study was a cross-sectional study using the data obtained from the Korea Environmental Exposure and Health ...
Seung-Ah Choe, Eunjung Kim, Mina Ha
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Delayed puberty versus hypogonadism: a challenge for the pediatrician [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2018 Constitutional delay of growth and puberty (CDGP) is the most common cause of delayed puberty (DP), is mainly found in males, and is characterized by short stature and delayed skeletal maturation.
Mauro Bozzola +5 more
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Clinical approach to the male with delayed puberty [PDF]
Archives of Endocrinology and MetabolismDisorders of pubertal onset and progression are a common cause for referral to paediatric endocrinologists, with delayed puberty in males being particularly frequent. Pubertal development depends on the hypothalamic-pituitary-testicular (HPT) axis, which
Rodolfo A. Rey +2 more
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EMBO Molecular Medicine, 2016 Early or late pubertal onset affects up to 5% of adolescents and is associated with adverse health and psychosocial outcomes. Self‐limited delayed puberty (DP) segregates predominantly in an autosomal dominant pattern, but the underlying genetic ...
Sasha R Howard +19 more
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Unraveling Delayed Puberty: A Rare Case of Congenital Hypogonadotropic Hypogonadism Masked by Celiac Disease and Plummer–Vinson Syndrome [PDF]
Clinical Case ReportsCongenital hypogonadotropic hypogonadism (CHH) is a rare disorder that results in delayed puberty and infertility due to impaired secretion of gonadotropin‐releasing hormone (GnRH).
Osama Ahmad +7 more
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Journal of Clinical Endocrinology & Metabolism, 1996 Delayed puberty can be defined as the absence of any signs of puberty in subjects that have attained an age at the upper limit (+2DS) for the onset of puberty, that means 13 years in girls and 14 years in boys. The causes of delayed puberty can be classified into three groups, functional temporary impairment in gonadotropin and sex steroid secretion ...
ANTONIAZZI, Franco +2 more
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DeckerMed Family Medicine, 2020 Although common, delayed puberty can be distressing to patients and families. Careful assessment is necessary to ensure appropriate physical and social development in patients that require intervention to reach pubertal milestones and achieve optimal growth.
Jessica Schmitt, Paul Boepple
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An Approach to the Patient with Delayed Puberty.
Journal of Clinical Endocrinology and Metabolism, 2022 Pediatric endocrinologists often evaluate and treat youth with delayed puberty. Stereotypically, these patients are 14-year-old young men who present due to lack of pubertal development.
J. Harrington, M. Palmert
semanticscholar +1 more source