Results 111 to 120 of about 1,980,181 (285)

Cardiovascular Health in Women—Across the Lifespan

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar   +5 more
wiley   +1 more source

Comparing Foster and Non‐Foster Adolescents: A Pilot Study on Relationships and Psychological Difficulties

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Adolescents experience substantial changes in their close relationships, which are linked to psychological adjustment. Research on relationships among adolescents in foster care is limited, especially in Germany. This pilot study (N = 30; 15 in foster families, 15 in biological families) explored how relationship qualities—measured by the ...
Julia Festini   +2 more
wiley   +1 more source

Expansion of the Phenotypic and Genotypic Spectrum for PRKAR1B‐Related Marbach–Schaaf Neurodevelopmental Syndrome: A Case Series

open access: yesClinical Genetics, EarlyView.
Comprehensive clinical description of 12 subjects with pathogenic PRKAR1B variants, including two heterozygous deletions supporting haploinsufficiency as a possible mechanism of disease, providing valuable insight into the pathophysiology of MASNS and setting a framework upon which to design future mechanistic studies of PKA signaling in brain ...
Sebastian Burkart   +17 more
wiley   +1 more source

Portrait of a Spectrum: Clinical and Genetic Characterization of a Large Cohort of Chromatinopathies—30 Years' Experience From a Third Level Center

open access: yesClinical Genetics, EarlyView.
Chromatinopathies (CP) are a growing group of rare genetic disorders characterized by cognitive deficits and growth abnormalities. This is the largest collection of CP to date, contributing to a deeper understanding of the landscape and diagnosis of these rare diseases, strongly improved by the use of large‐scale sequencing technologies.
Giulia Bruna Marchetti   +16 more
wiley   +1 more source

Empty sella Syndrome as a Cause of Hypopituitarism Case study

open access: yesDiyala Journal of Medicine, 2018
Background:Empty sella syndrome is the radiological appearance of an enlarged or deformed sella turcica which is partially or completely filled with cerebrospinal fluid .In 20-50% of patients there may be endocrinologic dysfunction, pan hypopituitarism ...
Yousif Baha'addin Ahmed
doaj   +2 more sources

A Current Perspective on Delayed Puberty and Its Management

open access: yesJCRPE
Delayed puberty is defined as the lack of development of secondary sex characteristics in childhood. Based on a review of the literature, delayed puberty can be divided into three main categories: (i) hypergonadotropic hypogonadism (congenital and ...
Ayhan Abacı, Özge Besci
doaj   +1 more source

Favorable Eruption Despite External Replacement Root Resorption in Delayed Replantation of Avulsed Teeth Treated With Regenerative Endodontics—An Observational Study

open access: yesDental Traumatology, EarlyView.
ABSTRACT Aim To assess the eruption patterns and progression of external replacement root resorption of eight teeth that were avulsed and had delayed replantation treated by regenerative endodontic treatment (RET). Methodology In total, 102 traumatised anterior teeth were treated with regenerative endodontic treatment (RET) between December 2016 and ...
Arieh Y. Kaufman   +3 more
wiley   +1 more source

Clobazam versus corticosteroid for developmental and epileptic encephalopathy with spike–wave activation in sleep ((D)EE‐SWAS): Results of a multicenter observational study

open access: yesEpilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathy with spike–wave activation in sleep ((D)EE‐SWAS) is associated with acquired cognitive and behavioral deficits. This international multicenter study aimed to compare cognitive and safety outcomes following initial treatment with corticosteroid and clobazam in patients not eligible for the ...
Marleen M. L. van Arnhem   +18 more
wiley   +1 more source

Age‐ and sex‐associated variability in lamotrigine prescription patterns and clearance

open access: yesEpilepsia, EarlyView.
Abstract Objective Lamotrigine is one of the most widely prescribed antiseizure medication (ASM) and mood stabilizer in the United States due to its favorable side‐effect profile, lower risk of teratogenicity, and minimal drug–drug interactions.
Charul Avachat   +4 more
wiley   +1 more source

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