Results 21 to 30 of about 1,980,181 (285)
Endocrine Connections, 2021 Background: Animal studies suggest that insulin-like growth factor 1 (IGF1 ) may influence the function of the hypothalamus–pituitary–testicular axis, especially in childhood, but the evidence in humans is scanty.
Rossella Cannarella +4 more
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LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling
JCI Insight, 2020 The initiation of puberty is driven by an upsurge in hypothalamic gonadotropin-releasing hormone (GnRH) secretion. In turn, GnRH secretion upsurge depends on the development of a complex GnRH neuroendocrine network during embryonic life. Although delayed
A. Mancini +19 more
semanticscholar +1 more source
JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2022 Puberty is a series of physical development and sexual maturation that aims to achieved reproductive capacity. The hypothalamic-pituitary-gonadal (HPG) axis has an important role in the normal process of puberty.
Dicky Moch Rizal, Nandia Septiyorini
doaj +1 more source
Delayed Puberty in Girls with Primary Amenorrhea: A Report of Cases
Journal of Biomedicine and Translational Research, 2021 Background:Female puberty starts when the pituitary hormone producing follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which will stimulate the ovaries to produce estrogen.
Fatinah Shahab +4 more
doaj +1 more source
Functional hypogonadism in adolescence: an overlooked cause of secondary hypogonadism
Endocrine Connections, 2023 Hypogonadism is a clinical syndrome resulting from failure to produce physiological concentrations of sex steroid hormones with accompanying symptoms, such as slowed growth and delayed pubertal maturation.
Rebeca Esquivel-Zuniga, Alan D Rogol
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Delayed Puberty—Phenotypic Diversity, Molecular Genetic Mechanisms, and Recent Discoveries
Endocrine reviews, 2019 This review presents a comprehensive discussion of the clinical condition of delayed puberty, a common presentation to the pediatric endocrinologist, which may present both diagnostic and prognostic challenges. Our understanding of the genetic control of
S. Howard, L. Dunkel
semanticscholar +1 more source
BMC Public Health, 2017 Background It is well known that excess adiposity during childhood may influence pubertal development. However, the extent to which body compositions vary in throughout puberty in boys and girls is currently unknown.
Fang He +5 more
doaj +1 more source
Urology Case Reports, 2015 Delayed puberty secondary to hypogonadism is commonly seen in sickle cell disease (SCD), affecting normal growth and development. The condition is rarely treated in SCD for fear of inducing priapism episodes.
Belinda F. Morrison +3 more
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Diagnosis and therapy of Kallmann syndrome in a boy (real case)
Медицинский совет, 2013 Timely and full sexual maturity of child is a challenge for both endocrinologists and general practitioners. Unfortunately, not all parents are aware when children generally reach puberty, so one shouldn’t hope that delayed puberty would be a common ...
O. A. Oganova
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