Results 101 to 110 of about 105,353 (261)

PRECOCIOUS PUBERTY

Ginekologia polska, 2011
Precocious puberty is an early sexual maturation before the age of 8 in case of girls and 9 in boys. There are two types: isosexual precocious puberty--characteristic are appropriate for the child's genetic and gonadal sex; and heterosexual precocious puberty--sexual characteristic are inappropriate for the genetic sex (feminizing syndrome in boys or ...
Grazyna, Jarzabek-Bielecka, Katarzyna, Warchoł-Biedermann, Elzbieta, Sowińska, Katarzyna, Wachowiak-Ochmańska   +3 more
  +5 more sources

Clinical spectrum of precocious puberty and its normal variants in children: insights from a seven-year review in a tertiary hospital, Calabar, Nigeria

Ibom Medical Journal
Context: Precocious puberty, clinically defined as the development of secondary sexual characteristics before 8 years of age in girls and 9 years in boys, represents a clinical spectrum that encompasses both pathological and non-pathological variants of
Eyong ME, Nsa EI, Uzomba CI, Eyong EM, Brown E, Ikobah JM, Etuk IS   +6 more
doaj   +1 more source

Association between MKRN3 and LIN28B polymorphisms and precocious puberty

BMC Genetics, 2018
Background The present study aimed to investigate the association between MKRN3 and LIN28B gene polymorphisms and precocious puberty in Korean boys and girls.
Bo Ram Yi, Hyun Jeong Kim, Hye Sook Park, Yoon Jeong Cho, Ju Young Kim, Jeong Yee, Jee Eun Chung, Joo Hee Kim, Kyung Eun Lee, Hye Sun Gwak   +9 more
doaj   +1 more source

Endocrinologic disorders and optic pathway gliomas in children with neurofibromatosis type 1 [PDF]

, 1997
Objective. To establish the prevalence of endocrinologic disorders in children with neurofibromatosis type 1 (NF1) and the relationship between these disorders and cerebral abnormalities on magnetic resonance imaging. Design.
Cnossen, M.H. (Marjon), Cooiman, L.C.M.G. (Linda C. M. G.), Goede-Bolder, A. (Arja) de, Halley, D. (Dicky), Muinck Keizer-Schrama, S.M.P.F. (Sabine) de, Niermeijer, M.F. (Martinus), Oranje, A.P. (Arnold), Simonsz, H.J. (Huib), Stam, E.N. (Esther N.), Stroink, H. (Hans)   +9 more
core   +1 more source

Replacing BPA: Structural Substitutes BPAF Binding to the Progesterone Receptor Elevates Breast Cancer Risk

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study demonstrates that bisphenol analogues, particularly BPAF, bind to progesterone receptor, promoting breast cancer cell proliferation, migration, and mammary tumor growth, indicating that bisphenol A substitutes may pose equal or greater health risks.
Xiaotong Ji, Peilin Li, Haoyang Wu, Linzhuo Shen, Xiaoyun Wu, Peiyun Jiang, Yating Li, Xiaozheng Zhang, Huifeng Yue   +8 more
wiley   +1 more source

Assessing Pubertal Timing, Duration, and Related Characteristics in ASXL‐Related Disorders: A Cross‐Sectional Caregiver Survey Analysis

American Journal of Medical Genetics Part A, Volume 200, Issue 1, Page 35-58, January 2026.
ABSTRACT Limited studies have been conducted on pubertal development in populations with pre‐existing medical conditions. More than 20‐fold increased risk of early puberty has been reported in neurodevelopmental disorders; however, this is a heterogeneous group.
Amanda Piring, Rebecca Hicks, Julia Sloan, Estefania Ramires‐Sanchez, Bianca E. Russell   +4 more
wiley   +1 more source

Psychological assessment of mothers and their daughters at the time of diagnosis of precocious puberty [PDF]

, 2015
BACKGROUND: Concerns about psychological distress are often used to justify treatment of girls with precocious puberty, but there is little evidence to support these concerns.
Berenbaum, Sheri A., Bryk, Kristina, Didrick, Paula, Donahue, Kelly L., Eugster, Erica A., Schoelwer, Melissa J.   +5 more
core   +1 more source

Severe Craniocerebral Injury in a Child Caused by Repetitive Cleaver Strikes: Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Severe open craniocerebral trauma caused by repetitive cleaver strikes in a child. ABSTRACT Severe craniocerebral injuries are rare in the pediatric population, especially open craniocerebral injuries caused by repeated slashes with sharp instruments.
Keyu Yan, Shuai Wang, Guanhui Li, Longlong Tian, Guozhu Sun   +4 more
wiley   +1 more source

Genetic Regulation of Puberty Timing in Humans. [PDF]

, 2015
Understanding the regulation of puberty timing has relevance to developmental and human biology and to the pathogenesis of various diseases. Recent large-scale genome-wide association studies on puberty timing and adult height, body mass index (BMI) and ...
Day, Felix R, Ong, Ken K, Perry, John RB
core   +2 more sources

Ovarian Sex Cord Stromal Tumor With Annular Tubules: A Rare Diagnosis in Young Women

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Ovarian sex cord‐stromal tumor with annular tubules (SCTAT) is a rare neoplasm with distinct clinicopathological features in its sporadic and syndromic forms, the latter commonly associated with Peutz‐Jeghers syndrome. Although imaging may suggest a sex cord‐stromal origin, definitive diagnosis relies on histopathological examination.
Prescillia Marques, Thiago Vieira, Raquel Brodbeck Ilgenfritz, Dusan Djokovic   +3 more
wiley   +1 more source