Results 121 to 130 of about 5,156,945 (309)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The Greatest Book You Will Never Read: Public Access Rights and the Orphan Works Dilemma [PDF]
, 2012 Copyright law aims to promote the dual goals of incentivizing production of literary and artistic works, and promoting public access and free speech.
Greismann, Libby
core +2 more sources
Scientific ReportsMany genital anaerobes, including Prevotella bivia, Peptostreptococcus anaerobius, and Dialister micraerophilus, are underexplored despite being Bacteria Associated with HIV Seroconversion, Inflammation, and immune Cells (BASICs).
Sydney G. Nelson +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Social Fragmentation and Public Goods Revisiting the Olson's Effect in Uttar Pradesh and Bihar [PDF]
A vast recent literature has stressed social fragmentation's negative impact on the provision of public goods. This is a key issue, given that public goods availability has been reckoned as crucial to economic development, while developing countries ...
Catherine Bros
core
[Review of] Leslie W. Dunbar, ed. Minority Report: What Has Happened to Blacks, Hispanics. American Indians, and Other Minorities in the Eighties [PDF]
, 1987 Six years since President Reagan took office, public policies related to the needs of the poor have been established which set back the gains of the Civil Rights movement. Although gains have been made, at least on the surface, the current administration\
Ortega, Carlos F.
core +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
The Politics of Public Health: A Response to Epstein [PDF]
, 2003 Conservatives are taking aim at the field of public health, targeting its efforts to understand and control environmental and social causes of disease. Richard Epstein and others contend that these efforts in fact undermine people’s health and well-being
Bloche, Maxwell Gregg +1 more
core +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Composition and dynamics of the adult nasal microbiome
MicrobiomeBackground The nasal microbiome, a dynamic assemblage of commensals and opportunistic pathogens, is crucial to human health. Results Using cross-sectional data from 1,608 adults and longitudinal sampling of 149 individuals over 8–22 months, we identified
Cindy M. Liu +19 more
doaj +1 more source